1.
J Org Chem
; 89(13): 9287-9297, 2024 Jul 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38896800
RESUMEN
A copper-catalyzed three-component coupling reaction of styrene oxide, aryl iodide, and carbon disulfide for the construction of ß-hydroxysulfides has been developed. In this process, readily available CS2 was used as the sulfur source to construct C-S bonds for the synthesis of phenyl-ß-hydroxysulfides and (benzo[d]thiazol)-ß-hydroxysulfides. This process features mild reaction conditions, simple operation, and wide substrate scope (>50 examples).