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1.
Getting a Grip on the Undrugged: Targeting ß-Catenin with Fragment-Based Methods.
ChemMedChem;
16(9): 1420-1424, 2021 05 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33275320
2.
Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis.
J Med Chem;
62(17): 7976-7997, 2019 09 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31365252
3.
An allometric pharmacokinetic/pharmacodynamics model for BI 893923, a novel IGF-1 receptor inhibitor.
Cancer Chemother Pharmacol;
79(3): 545-558, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28243682
4.
The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy.
Mol Cancer Ther;
16(10): 2223-2233, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28729397
5.
A comprehensive pharmacokinetic/pharmacodynamics analysis of the novel IGF1R/INSR inhibitor BI 893923 applying in vitro, in vivo and in silico modeling techniques.
Cancer Chemother Pharmacol;
77(6): 1303-14, 2016 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-27160688
6.
Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases.
Mol Cancer Ther;
15(10): 2388-2398, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27496137
7.
BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis.
Mol Cancer Ther;
14(12): 2762-72, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26438154
8.
Domino Hydroformylation-Wittig Reactions.
Angew Chem Int Ed Engl;
38(7): 969-971, 1999 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29711852
9.
Domino Hydroformylation/Knoevenagel/Hydrogenation Reactions This work was supported by the Fonds der Chemischen Industrie (Fellowship to S.K.Z.) and the Deutsche Forschungsgemeinschaft, as well as an Alfried Krupp Award for Young University Teachers from the Krupp foundation. We thank the companies BASF and Degussa for their gift of chemicals.
Angew Chem Int Ed Engl;
40(10): 1910-1913, 2001 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-11385670
10.
Diastereoselective hydroformylation of 2-substituted allylic o-DPPB-esters-on the origin of 1,2-asymmetric induction.
Chemistry;
9(2): 425-34, 2003 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-12532291
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