Craniocervical decompression with duraplasty and cerebellar tonsillectomy as treatment for Chiari malformation-I complicated with syringomyelia.

This study aimed to investigate the therapeutic effects of craniocervical decompression with duraplasty and cerebellar tonsillectomy for the treatment of Chiari malformation-I with syringomyelia (CM I-SM). From January 2005 to December 2011, 127 patients with CM I-SM underwent craniocervical decompression with duraplasty and cerebellar tonsillectomy and the therapeutic effects of these surgeries were evaluated using Tator scores. No patient in this study died or showed disease deterioration after the surgery. Re-examination by magnetic resonance imaging (MRI) showed that the cisterna magna was obviously larger after the operation in all but one patient. Moreover, syringomyelia (SM) was reduced in 76 patients. CM I-SM symptoms disappeared or decreased in 112 patients after following discharge. Follow-up was conducted in 84 of the patients and 79 of these patients exhibited improved symptoms. A second MRI re-examination showed that the cisterna magna was successfully constructed in 44 patients; 42 of these patients showed further eliminated or obviously reduced SM. Craniocervical decompression with duraplasty and cerebellar tonsillectomy achieved favorable therapeutic effects. Thus, craniocervical decompression with duraplasty and cerebellar tonsillectomy is a rational surgical approach with beneficial clinical effects. The proposed approach may have useful applications in the treatment of CM I-SM.

[Studies on the synthesis of dimethyl 4-hydroxy-4'-methoxy-5,6,5',6'-bismethylenedioxy biphenyl-2,2'-dicarboxylate--an essential metabolite of biphenyl diester].

This paper reports the synthesis of dimethyl 4-hydroxy-4'-methoxy-5,6,5',6'-bismethylenedioxybiphenyl-2,2'-dica rboxylate (II). Various conditions for bromination were tried to find the best one for synthesis of the key intermediate compound 6. After Ullmann condensation of 6 with 8 and hydrogenolysis, the title compound II was obtained. It was proved to be identical with the isolated metabolite of biphenyl diester by spectral data.

[Clinical study on the immune function of patients with obstructive jaundice].

Twenty-five patients with obstructive jaundice were investigated for immune function. Jaundiced patients' lymphocyte transformation (LCT), skin immune function (SIF) were lower than that of non-jaundiced patients, IgA, IgG and chemiluminescence (CL) of white blood cells were higher than that of non-jaundiced patients. LCT, lymphocyte count (LC), E-rosettes forming percentage (ERFP), SIF, IgA, IgG of the jaundiced patients were decreased with in 2 weeks after operation, CL was in a high level as compared to that of pre-operation. The immune function disturbance may be a reason of postoperative complications in jaundiced patients.

Clinical relevance of sHLA-G-mediated with better graft acceptance in early posttransplantation.

The aim of this study was to measure the level of soluble human leukocyte antigen (sHLA-G) in renal transplant patients, to determine the relationship between these levels and the occurrence of acute rejection episodes, and to identify their influence on graft acceptance early posttransplantation. sHLA-G, as measured by an enzyme-linked immunosorbent assay, was significantly increased (P < .01) early posttransplantation (3 months); the other group maintained low levels throughout the study. The latter group displayed a high incidence of acute rejection episodes and a lower clearance of serum creatinine with a longer period for hemoglobin to recover to normal (P < .01). These results suggested that HLA-G participates in the induction of immunologic tolerance in these recipients.

Adsorption of basic dye from aqueous solution onto fly ash.

The fly ash treated by H2SO4 was used as a low-cost adsorbent for the removal of a typical dye, methylene blue, from aqueous solution. An increase in the specific surface area and dye-adsorption capacity was observed after the acid treatment. The adsorption isotherm and kinetics of the treated fly ash were studied. The experimental results were fitted using Langmuir and Freundlich isotherms. It shows that the Freundlich isotherm is better in describing the adsorption process. Two kinetic models, pseudo-first order and pseudo-second order, were employed to analyze the kinetic data. It was found that the pseudo-second-order model is the better choice to describe the adsorption behavior. The thermodynamic study reveals that the enthalpy (delta H0) value is positive (5.63 kJ/mol), suggesting an endothermic nature of the adsorption.