Detalles de la búsqueda
1.
Human and nonclinical disposition of [14C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection.
Xenobiotica;
52(9-11): 973-985, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36546430
2.
Human pharmacokinetics prediction with an in vitro-in vivo correction factor approach and in vitro drug-drug interaction profile of bictegravir, a potent integrase-strand transfer inhibitor component in approved biktarvy® for the treatment of HIV-1 infection.
Xenobiotica;
52(12): 1020-1030, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36701274
3.
Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors.
Bioorg Med Chem Lett;
23(9): 2743-9, 2013 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23522834
4.
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration.
Bioorg Med Chem Lett;
21(18): 5521-7, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21813278
5.
In vitro investigations into the roles of CYP450 enzymes and drug transporters in the drug interactions of zanubrutinib, a covalent Bruton's tyrosine kinase inhibitor.
Pharmacol Res Perspect;
9(6): e00870, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34664792
6.
Human Mass Balance and Metabolite Profiling of [14 C]-Pamiparib, a Poly (ADP-Ribose) Polymerase Inhibitor, in Patients With Advanced Cancer.
Clin Pharmacol Drug Dev;
10(9): 1108-1120, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33876576
7.
Preparation and optimization of a series of 3-carboxamido-5-phenacylaminopyrazole bradykinin B1 receptor antagonists.
J Med Chem;
50(21): 5161-7, 2007 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-17880055
8.
Safety, efficacy, and pharmacokinetics of single-tablet elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide in virologically suppressed, HIV-infected children: a single-arm, open-label trial.
Lancet Child Adolesc Health;
1(1): 27-34, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-30169223
9.
Antiviral Activity, Safety, and Pharmacokinetics of Bictegravir as 10-Day Monotherapy in HIV-1-Infected Adults.
J Acquir Immune Defic Syndr;
75(1): 61-66, 2017 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28196003
10.
Pharmacokinetic drug-drug interaction study of ranolazine and metformin in subjects with type 2 diabetes mellitus.
Clin Pharmacol Drug Dev;
4(2): 121-9, 2015 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27128216
11.
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain.
ChemMedChem;
8(8): 1295-313, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23794260
Resultados
1 -
11
de 11
1
Próxima >
>>