RESUMEN
Objective: To analyze the clinical features, diagnosis, and treatment of desquamative interstitial pneumonia(DIP). Methods: The clinical manifestation, radiology, and pathology were analyzed in one patient with DIP in Beijing Hospital following review of the literatures. Results: The patient was a 55-year-old male presented with cough, shortness of breath and hypoxemia.Previous history of smoking and exposure to a variety of metals. A CT scan of the chest revealed diffuse ground-glass densities. A diagnosis of desquamative interstitial pneumonia (DIP) was confirmed by a thoracoscopic open lung biopsy. After treatment with hormone, the condition improved.A total of 66 cases were included in this study, the smoking groupof 20 cases, non-smokers of 46 cases.The smoking group was older than the non-smoking group [(47.5±12.1)years vs (26.1±22.5) years]; the present of chest pain, shortness of breath(4/20 vs 0/46; 8/20 vs 3/46) was higher in smoking group than in non-smoking group, and ground glass opacity in the chest image(15/20 vs 20/46) was also higher in smoking group than in non-smoking group.Pulmonary function showed more diffuse dysfunction(12/14 vs 6/13) in smoking group than in non-smoking group. Conclusions: As a rare disorder, DIP is associated with current or former cigarette smoking and many other risk factors. The clinical presents of non-smoker is atypical.DIP is curable to glucocorticoid and has a good prognosis.There is a possible of recurrence.
Asunto(s)
Enfermedades Genéticas Congénitas , Enfermedades Pulmonares Intersticiales , Biopsia , Bronquios , Bronquiolitis , Dolor en el Pecho , Tos , Glucocorticoides , Humanos , Gripe Humana , Pulmón , Masculino , Persona de Mediana Edad , Neumonía por Mycoplasma , Recurrencia , Factores de Riesgo , Tórax , Tomografía Computarizada por Rayos XRESUMEN
Over-utilization of germplasms that are resistant to the soybean cyst nematode (SCN) in soybean breeding programs can lead to genetic vulnerability in resistant cultivars. Resistant wild soybean (Glycine soja) is considered an invaluable gene source for increasing the genetic diversity of SCN resistance. In this study, we genotyped 23 G. soja accessions that are resistant to SCN race 3 for polymorphisms in the resistance genes, rhg1, Rhg4, and SHMT, and investigated their genetic relationship with eight Glycine max resistant cultivars. We identified 89 single nucleotide polymorphisms (SNPs) and 11 DNA insertion-deletions (InDels), of which 70 SNPs and 8 InDels were found in rhg1, 9 SNPs were found in Rhg4, and 10 SNPs and 3 InDels were found in SHMT. Nucleotide diversity was π = 0.00238 and θ = 0.00235, and haplotype diversity was 1.000. A phylogenetic tree comprising four clusters was constructed using sequence variations of the 23 G. soja and 8 G. max resistant accessions. Five G. soja accessions in subcluster A2, and four G. soja accessions in cluster B were genetically distant from G. max genotypes. Eight resistance-associated SNPs in the three resistance genes formed nine haplotypes in total. G. soja resistant accessions had different haplotypes (H2, H4, H5, H6, H7, and H8) compared with those of G. max (H1, H3, and H9). These results provide vital information on the use of wild soybeans for broadening the genetic base of SCN resistance.
Asunto(s)
Resistencia a la Enfermedad/genética , Glicina Hidroximetiltransferasa/genética , Glycine max/genética , Enfermedades de las Plantas/genética , Proteínas de Soja/genética , Alelos , Animales , Proteínas Portadoras/genética , Variación Genética , Genotipo , Haplotipos , Mutación INDEL/genética , Inmunidad Innata/genética , Nematodos/patogenicidad , Filogenia , Enfermedades de las Plantas/parasitología , Sitios de Carácter Cuantitativo/genética , Glycine max/parasitologíaRESUMEN
Studying frequency domain representation for the coherence between two signals is an important basic theoretical problem in the fundamental theories of signal processing. However, the old magnitude-squared coherence function (OMSCF) has been proved identical to 1, so that to cannot be used to extract any coherence information. Here, we will prove a core theorem in frequency domain coherence theories in signal processing, called as the double spectral theorem (DST). Based on the theorem, we presented the two types of new magnitude-squared coherence functions (MSCFs), called as the same type magnitude-squared coherence function (SMSCF) and the difference magnitude-squared coherence function (DMSCF) respectively, which were mathematically derived from DST and the conditions that they are equal to 1 or 0 can be theoretically derived from DST. Here, we further demonstrated that SMSCF and DMSCF could be used to exactly extract the coherence between two signals by each component.