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1.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

Hou, Yixuan J; Okuda, Kenichi; Edwards, Caitlin E; Martinez, David R; Asakura, Takanori; Dinnon, Kenneth H; Kato, Takafumi; Lee, Rhianna E; Yount, Boyd L; Mascenik, Teresa M; Chen, Gang; Olivier, Kenneth N; Ghio, Andrew; Tse, Longping V; Leist, Sarah R; Gralinski, Lisa E; Schäfer, Alexandra; Dang, Hong; Gilmore, Rodney; Nakano, Satoko; Sun, Ling; Fulcher, M Leslie; Livraghi-Butrico, Alessandra; Nicely, Nathan I; Cameron, Mark; Cameron, Cheryl; Kelvin, David J; de Silva, Aravinda; Margolis, David M; Markmann, Alena; Bartelt, Luther; Zumwalt, Ross; Martinez, Fernando J; Salvatore, Steven P; Borczuk, Alain; Tata, Purushothama R; Sontake, Vishwaraj; Kimple, Adam; Jaspers, Ilona; O'Neal, Wanda K; Randell, Scott H; Boucher, Richard C; Baric, Ralph S.

Cell; 2020 May 27.

Artículo en Inglés | MEDLINE | ID: covidwho-381993

2.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

Hou, Yixuan J; Okuda, Kenichi; Edwards, Caitlin E; Martinez, David R; Asakura, Takanori; Dinnon, Kenneth H; Kato, Takafumi; Lee, Rhianna E; Yount, Boyd L; Mascenik, Teresa M; Chen, Gang; Olivier, Kenneth N; Ghio, Andrew; Tse, Longping V; Leist, Sarah R; Gralinski, Lisa E; Schäfer, Alexandra; Dang, Hong; Gilmore, Rodney; Nakano, Satoko; Sun, Ling; Fulcher, M Leslie; Livraghi-Butrico, Alessandra; Nicely, Nathan I; Cameron, Mark; Cameron, Cheryl; Kelvin, David J; de Silva, Aravinda; Margolis, David M; Markmann, Alena; Bartelt, Luther; Zumwalt, Ross; Martinez, Fernando J; Salvatore, Steven P; Borczuk, Alain; Tata, Purushothama R; Sontake, Vishwaraj; Kimple, Adam; Jaspers, Ilona; O'Neal, Wanda K; Randell, Scott H; Boucher, Richard C; Baric, Ralph S.

Cell; 182(2): 429-446.e14, 2020 07 23.

Artículo en Inglés | MEDLINE | ID: mdl-32526206

3.

Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.

Han, Yuling; Duan, Xiaohua; Yang, Liuliu; Nilsson-Payant, Benjamin E; Wang, Pengfei; Duan, Fuyu; Tang, Xuming; Yaron, Tomer M; Zhang, Tuo; Uhl, Skyler; Bram, Yaron; Richardson, Chanel; Zhu, Jiajun; Zhao, Zeping; Redmond, David; Houghton, Sean; Nguyen, Duc-Huy T; Xu, Dong; Wang, Xing; Jessurun, Jose; Borczuk, Alain; Huang, Yaoxing; Johnson, Jared L; Liu, Yuru; Xiang, Jenny; Wang, Hui; Cantley, Lewis C; tenOever, Benjamin R; Ho, David D; Pan, Fong Cheng; Evans, Todd; Chen, Huanhuan Joyce; Schwartz, Robert E; Chen, Shuibing.

Nature; 589(7841): 270-275, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33116299

4.

Bi-allelic Mutations in Phe-tRNA Synthetase Associated with a Multi-system Pulmonary Disease Support Non-translational Function.

Xu, Zhiwen; Lo, Wing-Sze; Beck, David B; Schuch, Luise A; Oláhová, Monika; Kopajtich, Robert; Chong, Yeeting E; Alston, Charlotte L; Seidl, Elias; Zhai, Liting; Lau, Ching-Fun; Timchak, Donna; LeDuc, Charles A; Borczuk, Alain C; Teich, Andrew F; Juusola, Jane; Sofeso, Christina; Müller, Christoph; Pierre, Germaine; Hilliard, Tom; Turnpenny, Peter D; Wagner, Matias; Kappler, Matthias; Brasch, Frank; Bouffard, John Paul; Nangle, Leslie A; Yang, Xiang-Lei; Zhang, Mingjie; Taylor, Robert W; Prokisch, Holger; Griese, Matthias; Chung, Wendy K; Schimmel, Paul.

Am J Hum Genet; 103(1): 100-114, 2018 07 05.

Artículo en Inglés | MEDLINE | ID: mdl-29979980

5.

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome.

Middleton, Elizabeth A; He, Xue-Yan; Denorme, Frederik; Campbell, Robert A; Ng, David; Salvatore, Steven P; Mostyka, Maria; Baxter-Stoltzfus, Amelia; Borczuk, Alain C; Loda, Massimo; Cody, Mark J; Manne, Bhanu Kanth; Portier, Irina; Harris, Estelle S; Petrey, Aaron C; Beswick, Ellen J; Caulin, Aleah F; Iovino, Anthony; Abegglen, Lisa M; Weyrich, Andrew S; Rondina, Matthew T; Egeblad, Mikala; Schiffman, Joshua D; Yost, Christian Con.

Blood; 136(10): 1169-1179, 2020 09 03.

Artículo en Inglés | MEDLINE | ID: mdl-32597954

6.

Genomic Underpinnings of Tumor Behavior in In Situ and Early Lung Adenocarcinoma.

Qian, Jun; Zhao, Shilin; Zou, Yong; Rahman, S M Jamshedur; Senosain, Maria-Fernanda; Stricker, Thomas; Chen, Heidi; Powell, Charles A; Borczuk, Alain C; Massion, Pierre P.

Am J Respir Crit Care Med; 201(6): 697-706, 2020 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-31747302

7.

Pulmonary pathology of COVID-19: a review of autopsy studies.

Borczuk, Alain C.

Curr Opin Pulm Med; Publish Ahead of Print2021 Jan 04.

Artículo en Inglés | MEDLINE | ID: mdl-33399353

8.

COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City.

Borczuk, Alain C; Salvatore, Steven P; Seshan, Surya V; Patel, Sanjay S; Bussel, James B; Mostyka, Maria; Elsoukkary, Sarah; He, Bing; Del Vecchio, Claudia; Fortarezza, Francesco; Pezzuto, Federica; Navalesi, Paolo; Crisanti, Andrea; Fowkes, Mary E; Bryce, Clare H; Calabrese, Fiorella; Beasley, Mary Beth.

Mod Pathol; 33(11): 2156-2168, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-32879413

9.

Autopsy Findings in 32 Patients with COVID-19: A Single-Institution Experience.

Elsoukkary, Sarah S; Mostyka, Maria; Dillard, Alicia; Berman, Diana R; Ma, Lucy X; Chadburn, Amy; Yantiss, Rhonda K; Jessurun, Jose; Seshan, Surya V; Borczuk, Alain C; Salvatore, Steven P.

Pathobiology; : 1-13, 2020 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-32942274

10.

Wide Expression and Significance of Alternative Immune Checkpoint Molecules, B7x and HHLA2, in PD-L1-Negative Human Lung Cancers.

Cheng, Haiying; Borczuk, Alain; Janakiram, Murali; Ren, Xiaoxin; Lin, Juan; Assal, Amer; Halmos, Balazs; Perez-Soler, Roman; Zang, Xingxing.

Clin Cancer Res; 24(8): 1954-1964, 2018 04 15.

Artículo en Inglés | MEDLINE | ID: mdl-29374053

11.

Chondroid lipoma: multimodality imaging in a 9-year-old female.

Tannenbaum, Melissa; Colucci, Philip G; Baad, Michael; Borczuk, Alain C; Steigman, Shaun A; Kovanlikaya, Arzu.

Skeletal Radiol; 49(1): 161-169, 2020 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-31230114

12.

Micropapillary adenocarcinoma of lung: Morphological criteria and diagnostic reproducibility among pulmonary pathologists.

Monroig-Bosque, Paloma Del C; Morales-Rosado, Joel A; Roden, Anja C; Churg, Andrew; Barrios, Roberto; Cagle, Philip; Ge, Yimin; Allen, Timothy C; Smith, Maxwell L; Larsen, Brandon T; Sholl, Lynette M; Beasley, Mary B; Borczuk, Alain; Raparia, Kirtee; Ayala, Alberto; Tazelaar, Henry D; Miller, Ross; Kalhor, Neda; Moran, Cesar A; Ro, Jae Y.

Ann Diagn Pathol; 41: 43-50, 2019 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-31132651

13.

HHLA2, a New Immune Checkpoint Member of the B7 Family, Is Widely Expressed in Human Lung Cancer and Associated with EGFR Mutational Status.

Cheng, Haiying; Janakiram, Murali; Borczuk, Alain; Lin, Juan; Qiu, Wanglong; Liu, Huijie; Chinai, Jordan M; Halmos, Balazs; Perez-Soler, Roman; Zang, Xingxing.

Clin Cancer Res; 23(3): 825-832, 2017 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-27553831

14.

MET-GRB2 Signaling-Associated Complexes Correlate with Oncogenic MET Signaling and Sensitivity to MET Kinase Inhibitors.

Smith, Matthew A; Licata, Thomas; Lakhani, Aliya; Garcia, Marileila Varella; Schildhaus, Hans-Ulrich; Vuaroqueaux, Vincent; Halmos, Balazs; Borczuk, Alain C; Chen, Y Ann; Creelan, Benjamin C; Boyle, Theresa A; Haura, Eric B.

Clin Cancer Res; 23(22): 7084-7096, 2017 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-28855353

15.

Genome-wide association study of subclinical interstitial lung disease in MESA.

Manichaikul, Ani; Wang, Xin-Qun; Sun, Li; Dupuis, Josée; Borczuk, Alain C; Nguyen, Jennifer N; Raghu, Ganesh; Hoffman, Eric A; Onengut-Gumuscu, Suna; Farber, Emily A; Kaufman, Joel D; Rabinowitz, Dan; Stukovsky, Karen D Hinckley; Kawut, Steven M; Hunninghake, Gary M; Washko, George R; O'Connor, George T; Rich, Stephen S; Barr, R Graham; Lederer, David J.

Respir Res; 18(1): 97, 2017 05 18.

Artículo en Inglés | MEDLINE | ID: mdl-28521775

16.

A novel channelopathy in pulmonary arterial hypertension.

Ma, Lijiang; Roman-Campos, Danilo; Austin, Eric D; Eyries, Mélanie; Sampson, Kevin S; Soubrier, Florent; Germain, Marine; Trégouët, David-Alexandre; Borczuk, Alain; Rosenzweig, Erika Berman; Girerd, Barbara; Montani, David; Humbert, Marc; Loyd, James E; Kass, Robert S; Chung, Wendy K.

N Engl J Med; 369(4): 351-361, 2013 Jul 25.

Artículo en Inglés | MEDLINE | ID: mdl-23883380

17.

Prognostic significance of morphological growth patterns and mitotic index of epithelioid malignant peritoneal mesothelioma.

Krasinskas, Alyssa M; Borczuk, Alain C; Hartman, Douglas J; Chabot, John A; Taub, Robert N; Mogal, Ashish; Pingpank, James; Bartlett, David; Dacic, Sanja.

Histopathology; 68(5): 729-37, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26272336

18.

Therapeutic Interception of Early Lung Adenocarcinoma Progression: Not Just How, but When?

Borczuk, Alain C.

Am J Respir Crit Care Med; 203(1): 8-9, 2021 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-32846102

19.

Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.

Paliwal, Anupam; Temkin, Alexis M; Kerkel, Kristi; Yale, Alexander; Yotova, Iveta; Drost, Natalia; Lax, Simon; Nhan-Chang, Chia-Ling; Powell, Charles; Borczuk, Alain; Aviv, Abraham; Wapner, Ronald; Chen, Xiaowei; Nagy, Peter L; Schork, Nicholas; Do, Catherine; Torkamani, Ali; Tycko, Benjamin.

PLoS Genet; 9(8): e1003622, 2013 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24009515

20.

Clinical significance of blue-green neutrophil and monocyte cytoplasmic inclusions in SARS-CoV-2 positive critically ill patients.

Cantu, Miguel D; Towne, William S; Emmons, Foxwell N; Mostyka, Maria; Borczuk, Alain; Salvatore, Steven P; Yang, He S; Zhao, Zhen; Vasovic, Ljiljana V; Racine-Brzostek, Sabrina E.

Br J Haematol; 2020 May 26.

Artículo en Inglés | MEDLINE | ID: covidwho-378113

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SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.

Bi-allelic Mutations in Phe-tRNA Synthetase Associated with a Multi-system Pulmonary Disease Support Non-translational Function.

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome.

Genomic Underpinnings of Tumor Behavior in In Situ and Early Lung Adenocarcinoma.

Pulmonary pathology of COVID-19: a review of autopsy studies.

COVID-19 pulmonary pathology: a multi-institutional autopsy cohort from Italy and New York City.

Autopsy Findings in 32 Patients with COVID-19: A Single-Institution Experience.

Wide Expression and Significance of Alternative Immune Checkpoint Molecules, B7x and HHLA2, in PD-L1-Negative Human Lung Cancers.

Chondroid lipoma: multimodality imaging in a 9-year-old female.

Micropapillary adenocarcinoma of lung: Morphological criteria and diagnostic reproducibility among pulmonary pathologists.

HHLA2, a New Immune Checkpoint Member of the B7 Family, Is Widely Expressed in Human Lung Cancer and Associated with EGFR Mutational Status.

MET-GRB2 Signaling-Associated Complexes Correlate with Oncogenic MET Signaling and Sensitivity to MET Kinase Inhibitors.

Genome-wide association study of subclinical interstitial lung disease in MESA.

A novel channelopathy in pulmonary arterial hypertension.

Prognostic significance of morphological growth patterns and mitotic index of epithelioid malignant peritoneal mesothelioma.

Therapeutic Interception of Early Lung Adenocarcinoma Progression: Not Just How, but When?

Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.

Clinical significance of blue-green neutrophil and monocyte cytoplasmic inclusions in SARS-CoV-2 positive critically ill patients.