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1.

Type I interferon response impairs differentiation potential of pluripotent stem cells.

Eggenberger, Julie; Blanco-Melo, Daniel; Panis, Maryline; Brennand, Kristen J; tenOever, Benjamin R.

Proc Natl Acad Sci U S A; 116(4): 1384-1393, 2019 01 22.

Artículo en Inglés | MEDLINE | ID: mdl-30606801

2.

Integrating CRISPR Engineering and hiPSC-Derived 2D Disease Modeling Systems.

Rehbach, Kristina; Fernando, Michael B; Brennand, Kristen J.

J Neurosci; 40(6): 1176-1185, 2020 02 05.

Artículo en Inglés | MEDLINE | ID: mdl-32024766

3.

Spatial genome organization and cognition.

Rajarajan, Prashanth; Gil, Sergio Espeso; Brennand, Kristen J; Akbarian, Schahram.

Nat Rev Neurosci; 17(11): 681-691, 2016 11.

Artículo en Inglés | MEDLINE | ID: mdl-27708356

4.

A psychiatric disease-related circular RNA controls synaptic gene expression and cognition.

Zimmerman, Amber J; Hafez, Alexander K; Amoah, Stephen K; Rodriguez, Brian A; Dell'Orco, Michela; Lozano, Evelyn; Hartley, Brigham J; Alural, Begüm; Lalonde, Jasmin; Chander, Praveen; Webster, Maree J; Perlis, Roy H; Brennand, Kristen J; Haggarty, Stephen J; Weick, Jason; Perrone-Bizzozero, Nora; Brigman, Jonathan L; Mellios, Nikolaos.

Mol Psychiatry; 25(11): 2712-2727, 2020 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-31988434

5.

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.

Mertens, Jerome; Wang, Qiu-Wen; Kim, Yongsung; Yu, Diana X; Pham, Son; Yang, Bo; Zheng, Yi; Diffenderfer, Kenneth E; Zhang, Jian; Soltani, Sheila; Eames, Tameji; Schafer, Simon T; Boyer, Leah; Marchetto, Maria C; Nurnberger, John I; Calabrese, Joseph R; Ødegaard, Ketil J; McCarthy, Michael J; Zandi, Peter P; Alda, Martin; Alba, Martin; Nievergelt, Caroline M; Mi, Shuangli; Brennand, Kristen J; Kelsoe, John R; Gage, Fred H; Yao, Jun.

Nature; 527(7576): 95-9, 2015 Nov 05.

Artículo en Inglés | MEDLINE | ID: mdl-26524527

6.

Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics.

Matos, Marliette R; Ho, Seok-Man; Schrode, Nadine; Brennand, Kristen J.

Mol Cell Neurosci; 107: 103532, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32712198

7.

New considerations for hiPSC-based models of neuropsychiatric disorders.

Hoffman, Gabriel E; Schrode, Nadine; Flaherty, Erin; Brennand, Kristen J.

Mol Psychiatry; 24(1): 49-66, 2019 01.

Artículo en Inglés | MEDLINE | ID: mdl-29483625

8.

Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs.

Halpern, Madeline; Brennand, Kristen J; Gregory, James.

Neurobiol Dis; 132: 104562, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31381978

9.

Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypes.

Grochowski, Christopher M; Gu, Shen; Yuan, Bo; Tcw, Julia; Brennand, Kristen J; Sebat, Jonathan; Malhotra, Dheeraj; McCarthy, Shane; Rudolph, Uwe; Lindstrand, Anna; Chong, Zechen; Levy, Deborah L; Lupski, James R; Carvalho, Claudia M B.

Hum Mutat; 39(7): 939-946, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-29696747

10.

Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells.

Ho, Seok-Man; Hartley, Brigham J; Tcw, Julia; Beaumont, Michael; Stafford, Khalifa; Slesinger, Paul A; Brennand, Kristen J.

Methods; 101: 113-24, 2016 05 15.

Artículo en Inglés | MEDLINE | ID: mdl-26626326

11.

Modelling schizophrenia using human induced pluripotent stem cells.

Brennand, Kristen J; Simone, Anthony; Jou, Jessica; Gelboin-Burkhart, Chelsea; Tran, Ngoc; Sangar, Sarah; Li, Yan; Mu, Yangling; Chen, Gong; Yu, Diana; McCarthy, Shane; Sebat, Jonathan; Gage, Fred H.

Nature; 473(7346): 221-5, 2011 May 12.

Artículo en Inglés | MEDLINE | ID: mdl-21490598

12.

Erratum: Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.

Mertens, Jerome; Wang, Qiu-Wen; Kim, Yongsung; Yu, Diana X; Pham, Son; Yang, Bo; Zheng, Yi; Diffenderfer, Kenneth E; Zhang, Jian; Soltani, Sheila; Eames, Tameji; Schafer, Simon T; Boyer, Leah; Marchetto, Maria C; Nurnberger, John I; Calabrese, Joseph R; Oedegaard, Ketil J; McCarthy, Michael J; Zandi, Peter P; Alda, Martin; Nievergelt, Caroline M; Mi, Shuangli; Brennand, Kristen J; Kelsoe, John R; Gage, Fred H; Yao, Jun.

Nature; 530(7589): 242, 2016 Feb 11.

Artículo en Inglés | MEDLINE | ID: mdl-26605530

13.

Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease.

Kocerha, Jannet; Dwivedi, Yogesh; Brennand, Kristen J.

Mol Psychiatry; 20(6): 677-684, 2015 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-25824307

14.

The Pharmacogenomics of Bipolar Disorder study (PGBD): identification of genes for lithium response in a prospective sample.

Oedegaard, Ketil J; Alda, Martin; Anand, Anit; Andreassen, Ole A; Balaraman, Yokesh; Berrettini, Wade H; Bhattacharjee, Abesh; Brennand, Kristen J; Burdick, Katherine E; Calabrese, Joseph R; Calkin, Cynthia V; Claasen, Ana; Coryell, William H; Craig, David; DeModena, Anna; Frye, Mark; Gage, Fred H; Gao, Keming; Garnham, Julie; Gershon, Elliot; Jakobsen, Petter; Leckband, Susan G; McCarthy, Michael J; McInnis, Melvin G; Maihofer, Adam X; Mertens, Jerome; Morken, Gunnar; Nievergelt, Caroline M; Nurnberger, John; Pham, Son; Schoeyen, Helle; Shekhtman, Tatyana; Shilling, Paul D; Szelinger, Szabolcs; Tarwater, Bruce; Yao, Jun; Zandi, Peter P; Kelsoe, John R.

BMC Psychiatry; 16: 129, 2016 May 05.

Artículo en Inglés | MEDLINE | ID: mdl-27150464

15.

Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises.

Marchetto, Maria C; Brennand, Kristen J; Boyer, Leah F; Gage, Fred H.

Hum Mol Genet; 20(R2): R109-15, 2011 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-21828073

16.

Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia.

Brennand, Kristen J; Gage, Fred H.

Stem Cells; 29(12): 1915-22, 2011 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-22009633

17.

Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines.

Woods, Niels-Bjarne; Parker, Aaron S; Moraghebi, Roksana; Lutz, Margaret K; Firth, Amy L; Brennand, Kristen J; Berggren, W Travis; Raya, Angel; Izpisúa Belmonte, Juan Carlos; Gage, Fred H; Verma, Inder M.

Stem Cells; 29(7): 1158-64, 2011 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-21544903

18.

Parsing the Functional Impact of Noncoding Genetic Variants in the Brain Epigenome.

Powell, Samuel K; O'Shea, Callan; Brennand, Kristen J; Akbarian, Schahram.

Biol Psychiatry; 89(1): 65-75, 2021 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-33131715

19.

Analysis framework and experimental design for evaluating synergy-driving gene expression.

Schrode, Nadine; Seah, Carina; Deans, P J Michael; Hoffman, Gabriel; Brennand, Kristen J.

Nat Protoc; 16(2): 812-840, 2021 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-33432232

20.

Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection.

Dobrindt, Kristina; Hoagland, Daisy A; Seah, Carina; Kassim, Bibi; O'Shea, Callan P; Murphy, Aleta; Iskhakova, Marina; Fernando, Michael B; Powell, Samuel K; Deans, P J Michael; Javidfar, Ben; Peter, Cyril; Møller, Rasmus; Uhl, Skyler A; Garcia, Meilin Fernandez; Kimura, Masaki; Iwasawa, Kentaro; Crary, John F; Kotton, Darrell N; Takebe, Takanori; Huckins, Laura M; tenOever, Benjamin R; Akbarian, Schahram; Brennand, Kristen J.

Stem Cell Reports; 2021 Feb 13.

Artículo en Inglés | MEDLINE | ID: mdl-33636110

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