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1.

Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase, a Key Drug Target for COVID-19.

Chien, Minchen; Anderson, Thomas K; Jockusch, Steffen; Tao, Chuanjuan; Li, Xiaoxu; Kumar, Shiv; Russo, James J; Kirchdoerfer, Robert N; Ju, Jingyue.

J Proteome Res; 19(11): 4690-4697, 2020 11 06.

Artículo en Inglés | MEDLINE | ID: mdl-32692185

2.

Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array.

Stranges, P Benjamin; Palla, Mirkó; Kalachikov, Sergey; Nivala, Jeff; Dorwart, Michael; Trans, Andrew; Kumar, Shiv; Porel, Mintu; Chien, Minchen; Tao, Chuanjuan; Morozova, Irina; Li, Zengmin; Shi, Shundi; Aberra, Aman; Arnold, Cleoma; Yang, Alexander; Aguirre, Anne; Harada, Eric T; Korenblum, Daniel; Pollard, James; Bhat, Ashwini; Gremyachinskiy, Dmitriy; Bibillo, Arek; Chen, Roger; Davis, Randy; Russo, James J; Fuller, Carl W; Roever, Stefan; Ju, Jingyue; Church, George M.

Proc Natl Acad Sci U S A; 113(44): E6749-E6756, 2016 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-27729524

3.

Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array.

Fuller, Carl W; Kumar, Shiv; Porel, Mintu; Chien, Minchen; Bibillo, Arek; Stranges, P Benjamin; Dorwart, Michael; Tao, Chuanjuan; Li, Zengmin; Guo, Wenjing; Shi, Shundi; Korenblum, Daniel; Trans, Andrew; Aguirre, Anne; Liu, Edward; Harada, Eric T; Pollard, James; Bhat, Ashwini; Cech, Cynthia; Yang, Alexander; Arnold, Cleoma; Palla, Mirkó; Hovis, Jennifer; Chen, Roger; Morozova, Irina; Kalachikov, Sergey; Russo, James J; Kasianowicz, John J; Davis, Randy; Roever, Stefan; Church, George M; Ju, Jingyue.

Proc Natl Acad Sci U S A; 113(19): 5233-8, 2016 May 10.

Artículo en Inglés | MEDLINE | ID: mdl-27091962

4.

A novel class of small RNAs bind to MILI protein in mouse testes.

Aravin, Alexei; Gaidatzis, Dimos; Pfeffer, Sébastien; Lagos-Quintana, Mariana; Landgraf, Pablo; Iovino, Nicola; Morris, Patricia; Brownstein, Michael J; Kuramochi-Miyagawa, Satomi; Nakano, Toru; Chien, Minchen; Russo, James J; Ju, Jingyue; Sheridan, Robert; Sander, Chris; Zavolan, Mihaela; Tuschl, Thomas.

Nature; 442(7099): 203-7, 2006 Jul 13.

Artículo en Inglés | MEDLINE | ID: mdl-16751777

5.

Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase.

Chien, Minchen; Anderson, Thomas K; Jockusch, Steffen; Tao, Chuanjuan; Kumar, Shiv; Li, Xiaoxu; Russo, James J; Kirchdoerfer, Robert N; Ju, Jingyue.

bioRxiv; 2020 Mar 20.

Artículo en Inglés | MEDLINE | ID: mdl-32511320

6.

A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19.

Jockusch, Steffen; Tao, Chuanjuan; Li, Xiaoxu; Anderson, Thomas K; Chien, Minchen; Kumar, Shiv; Russo, James J; Kirchdoerfer, Robert N; Ju, Jingyue.

Antiviral Res; 180: 104857, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32562705

7.

Nucleotide analogues as inhibitors of SARS-CoV Polymerase.

Ju, Jingyue; Li, Xiaoxu; Kumar, Shiv; Jockusch, Steffen; Chien, Minchen; Tao, Chuanjuan; Morozova, Irina; Kalachikov, Sergey; Kirchdoerfer, Robert N; Russo, James J.

Pharmacol Res Perspect; 8(6): e00674, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-33124786

8.

Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir.

Jockusch, Steffen; Tao, Chuanjuan; Li, Xiaoxu; Chien, Minchen; Kumar, Shiv; Morozova, Irina; Kalachikov, Sergey; Russo, James J; Ju, Jingyue.

Sci Rep; 10(1): 16577, 2020 10 06.

Artículo en Inglés | MEDLINE | ID: mdl-33024223

9.

PEG-labeled nucleotides and nanopore detection for single molecule DNA sequencing by synthesis.

Kumar, Shiv; Tao, Chuanjuan; Chien, Minchen; Hellner, Brittney; Balijepalli, Arvind; Robertson, Joseph W F; Li, Zengmin; Russo, James J; Reiner, Joseph E; Kasianowicz, John J; Ju, Jingyue.

Sci Rep; 2: 684, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-23002425

10.

Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4).

Strug, Lisa J; Clarke, Tara; Chiang, Theodore; Chien, Minchen; Baskurt, Zeynep; Li, Weili; Dorfman, Ruslan; Bali, Bhavna; Wirrell, Elaine; Kugler, Steven L; Mandelbaum, David E; Wolf, Steven M; McGoldrick, Patricia; Hardison, Huntley; Novotny, Edward J; Ju, Jingyue; Greenberg, David A; Russo, James J; Pal, Deb K.

Eur J Hum Genet; 17(9): 1171-81, 2009 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-19172991

11.

Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia.

Fulci, Valerio; Chiaretti, Sabina; Goldoni, Marina; Azzalin, Gianluca; Carucci, Nicoletta; Tavolaro, Simona; Castellano, Leandro; Magrelli, Armando; Citarella, Franca; Messina, Monica; Maggio, Roberta; Peragine, Nadia; Santangelo, Simona; Mauro, Francesca Romana; Landgraf, Pablo; Tuschl, Thomas; Weir, David B; Chien, Minchen; Russo, James J; Ju, Jingyue; Sheridan, Robert; Sander, Chris; Zavolan, Mihaela; Guarini, Anna; Foà, Robin; Macino, Giuseppe.

Blood; 109(11): 4944-51, 2007 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-17327404

12.

Cellular cofactors affecting hepatitis C virus infection and replication.

Randall, Glenn; Panis, Maryline; Cooper, Jacob D; Tellinghuisen, Timothy L; Sukhodolets, Karen E; Pfeffer, Sebastien; Landthaler, Markus; Landgraf, Pablo; Kan, Sherry; Lindenbach, Brett D; Chien, Minchen; Weir, David B; Russo, James J; Ju, Jingyue; Brownstein, Michael J; Sheridan, Robert; Sander, Chris; Zavolan, Mihaela; Tuschl, Thomas; Rice, Charles M.

Proc Natl Acad Sci U S A; 104(31): 12884-9, 2007 Jul 31.

Artículo en Inglés | MEDLINE | ID: mdl-17616579

13.

A mammalian microRNA expression atlas based on small RNA library sequencing.

Landgraf, Pablo; Rusu, Mirabela; Sheridan, Robert; Sewer, Alain; Iovino, Nicola; Aravin, Alexei; Pfeffer, Sébastien; Rice, Amanda; Kamphorst, Alice O; Landthaler, Markus; Lin, Carolina; Socci, Nicholas D; Hermida, Leandro; Fulci, Valerio; Chiaretti, Sabina; Foà, Robin; Schliwka, Julia; Fuchs, Uta; Novosel, Astrid; Müller, Roman-Ulrich; Schermer, Bernhard; Bissels, Ute; Inman, Jason; Phan, Quang; Chien, Minchen; Weir, David B; Choksi, Ruchi; De Vita, Gabriella; Frezzetti, Daniela; Trompeter, Hans-Ingo; Hornung, Veit; Teng, Grace; Hartmann, Gunther; Palkovits, Miklos; Di Lauro, Roberto; Wernet, Peter; Macino, Giuseppe; Rogler, Charles E; Nagle, James W; Ju, Jingyue; Papavasiliou, F Nina; Benzing, Thomas; Lichter, Peter; Tam, Wayne; Brownstein, Michael J; Bosio, Andreas; Borkhardt, Arndt; Russo, James J; Sander, Chris; Zavolan, Mihaela.

Cell; 129(7): 1401-14, 2007 Jun 29.

Artículo en Inglés | MEDLINE | ID: mdl-17604727

14.

Prognostic Values of microRNAs in Colorectal Cancer.

Xi, Yaguang; Formentini, Andrea; Chien, Minchen; Weir, David B; Russo, James J; Ju, Jingyue; Kornmann, Marko; Ju, Jingfang.

Biomark Insights; 2: 113-121, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-18079988

15.

Two somatic biallelic lesions within and near SMAD4 in a human breast cancer cell line.

Jakob, John; Nagase, Satoru; Gazdar, Adi; Chien, Minchen; Morozova, Irina; Russo, James J; Nandula, Subhadra V; Murty, Vundavalli V V S; Li, Chi-Ming; Tycko, Benjamin; Parsons, Ramon.

Genes Chromosomes Cancer; 42(4): 372-83, 2005 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-15645498

16.

The developmental miRNA profiles of zebrafish as determined by small RNA cloning.

Chen, Po Yu; Manninga, Heiko; Slanchev, Krasimir; Chien, Minchen; Russo, James J; Ju, Jingyue; Sheridan, Robert; John, Bino; Marks, Debora S; Gaidatzis, Dimos; Sander, Chris; Zavolan, Mihaela; Tuschl, Thomas.

Genes Dev; 19(11): 1288-93, 2005 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-15937218

17.

Identification of microRNAs of the herpesvirus family.

Pfeffer, Sébastien; Sewer, Alain; Lagos-Quintana, Mariana; Sheridan, Robert; Sander, Chris; Grässer, Friedrich A; van Dyk, Linda F; Ho, C Kiong; Shuman, Stewart; Chien, Minchen; Russo, James J; Ju, Jingyue; Randall, Glenn; Lindenbach, Brett D; Rice, Charles M; Simon, Viviana; Ho, David D; Zavolan, Mihaela; Tuschl, Thomas.

Nat Methods; 2(4): 269-76, 2005 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-15782219

18.

Identification of virus-encoded microRNAs.

Pfeffer, Sébastien; Zavolan, Mihaela; Grässer, Friedrich A; Chien, Minchen; Russo, James J; Ju, Jingyue; John, Bino; Enright, Anton J; Marks, Debora; Sander, Chris; Tuschl, Thomas.

Science; 304(5671): 734-6, 2004 Apr 30.

Artículo en Inglés | MEDLINE | ID: mdl-15118162

19.

The genomic sequence of the accidental pathogen Legionella pneumophila.

Chien, Minchen; Morozova, Irina; Shi, Shundi; Sheng, Huitao; Chen, Jing; Gomez, Shawn M; Asamani, Gifty; Hill, Kendra; Nuara, John; Feder, Marc; Rineer, Justin; Greenberg, Joseph J; Steshenko, Valeria; Park, Samantha H; Zhao, Baohui; Teplitskaya, Elita; Edwards, John R; Pampou, Sergey; Georghiou, Anthi; Chou, I-Chun; Iannuccilli, William; Ulz, Michael E; Kim, Dae H; Geringer-Sameth, Alex; Goldsberry, Curtis; Morozov, Pavel; Fischer, Stuart G; Segal, Gil; Qu, Xiaoyan; Rzhetsky, Andrey; Zhang, Peisen; Cayanis, Eftihia; De Jong, Pieter J; Ju, Jingyue; Kalachikov, Sergey; Shuman, Howard A; Russo, James J.

Science; 305(5692): 1966-8, 2004 Sep 24.

Artículo en Inglés | MEDLINE | ID: mdl-15448271

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