Búsqueda | Portal de Búsqueda de la BVS España

1.

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy.

Zhu, Zheng; Chu, Hin; Wen, Lei; Yuan, Shuofeng; Chik, Kenn Ka-Heng; Yuen, Terrence Tsz-Tai; Yip, Cyril Chik-Yan; Wang, Dong; Zhou, Jie; Yin, Feifei; Jin, Dong-Yan; Kok, Kin-Hang; Yuen, Kwok-Yung; Chan, Jasper Fuk-Woo.

Int J Mol Sci; 20(2)2019 Jan 17.

Artículo en Inglés | MEDLINE | ID: mdl-30658479

2.

Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real-time RT-PCR assay targeting the 5'-untranslated region of Zika virus.

Chan, Jasper Fuk-Woo; Yip, Cyril Chik-Yan; Tee, Kah-Meng; Zhu, Zheng; Tsang, Jessica Oi-Ling; Chik, Kenn Ka-Heng; Tsang, Terance Gi-Wai; Chan, Chris Chung-Sing; Poon, Vincent Kwok-Man; Sridhar, Siddharth; Yin, Feifei; Hung, Ivan Fan-Ngai; Chau, Sandy Ka-Yee; Zhang, Anna Jinxia; Chan, Kwok-Hung; Yuen, Kwok-Yung.

Trop Med Int Health; 22(5): 594-603, 2017 05.

Artículo en Inglés | MEDLINE | ID: mdl-28214373

3.

Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies.

Zhou, Dongyan; Chan, Jasper Fuk-Woo; Zhou, Biao; Zhou, Runhong; Li, Shuang; Shan, Sisi; Liu, Li; Zhang, Anna Jinxia; Chen, Serena J; Chan, Chris Chung-Sing; Xu, Haoran; Poon, Vincent Kwok-Man; Yuan, Shuofeng; Li, Cun; Chik, Kenn Ka-Heng; Chan, Chris Chun-Yiu; Cao, Jianli; Chan, Chun-Yin; Kwan, Ka-Yi; Du, Zhenglong; Lau, Thomas Tsz-Kan; Zhang, Qi; Zhou, Jie; To, Kelvin Kai-Wang; Zhang, Linqi; Ho, David D; Yuen, Kwok-Yung; Chen, Zhiwei.

Cell Host Microbe; 29(4): 551-563.e5, 2021 04 14.

Artículo en Inglés | MEDLINE | ID: mdl-33657424

4.

Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters.

Yuan, Shuofeng; Wang, Runming; Chan, Jasper Fuk-Woo; Zhang, Anna Jinxia; Cheng, Tianfan; Chik, Kenn Ka-Heng; Ye, Zi-Wei; Wang, Suyu; Lee, Andrew Chak-Yiu; Jin, Lijian; Li, Hongyan; Jin, Dong-Yan; Yuen, Kwok-Yung; Sun, Hongzhe.

Nat Microbiol; 5(11): 1439-1448, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-33028965

5.

Metabolic Profiling Reveals Significant Perturbations of Intracellular Glucose Homeostasis in Enterovirus-Infected Cells.

Zou, Zijiao; Tsang, Jessica Oi-Ling; Yan, Bingpeng; Chik, Kenn Ka-Heng; Chan, Chris Chun-Yiu; Cao, Jianli; Liang, Ronghui; Tang, Kaiming; Yin, Feifei; Ye, Zi-Wei; Chu, Hin; Chan, Jasper Fuk-Woo; Yuan, Shuofeng; Yuen, Kwok-Yung.

Metabolites; 10(8)2020 Jul 23.

Artículo en Inglés | MEDLINE | ID: mdl-32717953

6.

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19).

Yuan, Shuofeng; Chan, Chris Chun-Yiu; Chik, Kenn Ka-Heng; Tsang, Jessica Oi-Ling; Liang, Ronghui; Cao, Jianli; Tang, Kaiming; Cai, Jian-Piao; Ye, Zi-Wei; Yin, Feifei; To, Kelvin Kai-Wang; Chu, Hin; Jin, Dong-Yan; Hung, Ivan Fan-Ngai; Yuen, Kwok-Yung; Chan, Jasper Fuk-Woo.

Viruses; 12(6)2020 06 10.

Artículo en Inglés | MEDLINE | ID: mdl-32532085

7.

Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study.

Chu, Hin; Chan, Jasper Fuk-Woo; Yuen, Terrence Tsz-Tai; Shuai, Huiping; Yuan, Shuofeng; Wang, Yixin; Hu, Bingjie; Yip, Cyril Chik-Yan; Tsang, Jessica Oi-Ling; Huang, Xiner; Chai, Yue; Yang, Dong; Hou, Yuxin; Chik, Kenn Ka-Heng; Zhang, Xi; Fung, Agnes Yim-Fong; Tsoi, Hoi-Wah; Cai, Jian-Piao; Chan, Wan-Mui; Ip, Jonathan Daniel; Chu, Allen Wing-Ho; Zhou, Jie; Lung, David Christopher; Kok, Kin-Hang; To, Kelvin Kai-Wang; Tsang, Owen Tak-Yin; Chan, Kwok-Hung; Yuen, Kwok-Yung.

Lancet Microbe; 1(1): e14-e23, 2020 May.

Artículo en Inglés | MEDLINE | ID: mdl-32835326

8.

Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus.

Yuan, Shuofeng; Chan, Jasper Fuk-Woo; Ye, Zi-Wei; Wen, Lei; Tsang, Terance Gi-Wai; Cao, Jianli; Huang, Jingjing; Chan, Chris Chun-Yiu; Chik, Kenn Ka-Heng; Choi, Garnet Kwan-Yue; Cai, Jian-Piao; Yin, Feifei; Chu, Hin; Liang, Mifang; Jin, Dong-Yan; Yuen, Kwok-Yung.

Viruses; 11(4)2019 04 25.

Artículo en Inglés | MEDLINE | ID: mdl-31027241

9.

The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy.

Chan, Jasper Fuk-Woo; Zhu, Zheng; Chu, Hin; Yuan, Shuofeng; Chik, Kenn Ka-Heng; Chan, Chris Chung-Sing; Poon, Vincent Kwok-Man; Yip, Cyril Chik-Yan; Zhang, Xi; Tsang, Jessica Oi-Ling; Zou, Zijiao; Tee, Kah-Meng; Shuai, Huiping; Lu, Gang; Yuen, Kwok-Yung.

Antiviral Res; 160: 38-47, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30326204

10.

Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor.

Chan, Jasper Fuk-Woo; Chik, Kenn Ka-Heng; Yuan, Shuofeng; Yip, Cyril Chik-Yan; Zhu, Zheng; Tee, Kah-Meng; Tsang, Jessica Oi-Ling; Chan, Chris Chung-Sing; Poon, Vincent Kwok-Man; Lu, Gang; Zhang, Anna Jinxia; Lai, Kin-Kui; Chan, Kwok-Hung; Kao, Richard Yi-Tsun; Yuen, Kwok-Yung.

Antiviral Res; 141: 29-37, 2017 05.

Artículo en Inglés | MEDLINE | ID: mdl-28185815

11.

Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo.

Yuan, Shuofeng; Chan, Jasper Fuk-Woo; den-Haan, Helena; Chik, Kenn Ka-Heng; Zhang, Anna Jinxia; Chan, Chris Chung-Sing; Poon, Vincent Kwok-Man; Yip, Cyril Chik-Yan; Mak, Winger Wing-Nga; Zhu, Zheng; Zou, Zijiao; Tee, Kah-Meng; Cai, Jian-Piao; Chan, Kwok-Hung; de la Peña, Jorge; Pérez-Sánchez, Horacio; Cerón-Carrasco, José Pedro; Yuen, Kwok-Yung.

Antiviral Res; 145: 33-43, 2017 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-28712942

12.

Hemagglutinin of influenza A virus binds specifically to cell surface nucleolin and plays a role in virus internalization.

Chan, Che-Man; Chu, Hin; Zhang, Anna Jinxia; Leung, Lai-Han; Sze, Kong-Hung; Kao, Richard Yi-Tsun; Chik, Kenn Ka-Heng; To, Kelvin Kai-Wang; Chan, Jasper Fuk-Woo; Chen, Honglin; Jin, Dong-Yan; Liu, Liang; Yuen, Kwok-Yung.

Virology; 494: 78-88, 2016 07.

Artículo en Inglés | MEDLINE | ID: mdl-27085069

13.

Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons.

Chan, Jasper Fuk-Woo; Zhang, Anna Jinxia; Chan, Chris Chung-Sing; Yip, Cyril Chik-Yan; Mak, Winger Wing-Nga; Zhu, Houshun; Poon, Vincent Kwok-Man; Tee, Kah-Meng; Zhu, Zheng; Cai, Jian-Piao; Tsang, Jessica Oi-Ling; Chik, Kenn Ka-Heng; Yin, Feifei; Chan, Kwok-Hung; Kok, Kin-Hang; Jin, Dong-Yan; Au-Yeung, Rex Kwok-Him; Yuen, Kwok-Yung.

EBioMedicine; 14: 112-122, 2016 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-27884655

14.

Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs.

Chan, Jasper Fuk-Woo; Yip, Cyril Chik-Yan; Tsang, Jessica Oi-Ling; Tee, Kah-Meng; Cai, Jian-Piao; Chik, Kenn Ka-Heng; Zhu, Zheng; Chan, Chris Chung-Sing; Choi, Garnet Kwan-Yue; Sridhar, Siddharth; Zhang, Anna Jinxia; Lu, Gang; Chiu, Kin; Lo, Amy Cheuk-Yin; Tsao, Sai-Wah; Kok, Kin-Hang; Jin, Dong-Yan; Chan, Kwok-Hung; Yuen, Kwok-Yung.

Emerg Microbes Infect; 5: e93, 2016 Aug 24.

Artículo en Inglés | MEDLINE | ID: mdl-27553173

Portal de Búsqueda de la BVS España

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: