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1.

Absence of vaccine-enhanced disease with unexpected positive protection against SARS-CoV-2 by inactivated vaccine given within three days of virus challenge in Syrian hamster model.

Li, Can; Chen, Yan-Xia; Liu, Fei-Fei; Lee, Andrew Chak-Yiu; Zhao, Yan; Ye, Zhan-Hong; Cai, Jian-Piao; Chu, Hin; Zhang, Rui-Qi; Chan, Kwok-Hung; Chiu, Kelvin Hei-Yeung; Lung, David Christopher; Sridhar, Siddharth; Hung, Ivan Fan-Ngai; To, Kelvin Kai-Wang; Zhang, Anna Jin-Xia; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung.

Clin Infect Dis; 2021 Jan 30.

Artículo en Inglés | MEDLINE | ID: mdl-33515458

2.

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.

Chan, Jasper Fuk-Woo; Yuan, Shuofeng; Kok, Kin-Hang; To, Kelvin Kai-Wang; Chu, Hin; Yang, Jin; Xing, Fanfan; Liu, Jieling; Yip, Cyril Chik-Yan; Poon, Rosana Wing-Shan; Tsoi, Hoi-Wah; Lo, Simon Kam-Fai; Chan, Kwok-Hung; Poon, Vincent Kwok-Man; Chan, Wan-Mui; Ip, Jonathan Daniel; Cai, Jian-Piao; Cheng, Vincent Chi-Chung; Chen, Honglin; Hui, Christopher Kim-Ming; Yuen, Kwok-Yung.

Lancet; 395(10223): 514-523, 2020 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-31986261

3.

Differentiated human airway organoids to assess infectivity of emerging influenza virus.

Zhou, Jie; Li, Cun; Sachs, Norman; Chiu, Man Chun; Wong, Bosco Ho-Yin; Chu, Hin; Poon, Vincent Kwok-Man; Wang, Dong; Zhao, Xiaoyu; Wen, Lei; Song, Wenjun; Yuan, Shuofeng; Wong, Kenneth Kak-Yuen; Chan, Jasper Fuk-Woo; To, Kelvin Kai-Wang; Chen, Honglin; Clevers, Hans; Yuen, Kwok-Yung.

Proc Natl Acad Sci U S A; 115(26): 6822-6827, 2018 06 26.

Artículo en Inglés | MEDLINE | ID: mdl-29891677

4.

Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages.

Zhao, Xiaoyu; Chu, Hin; Wong, Bosco Ho-Yin; Chiu, Man Chun; Wang, Dong; Li, Cun; Liu, Xiaojuan; Yang, Dong; Poon, Vincent Kwok-Man; Cai, Jianpiao; Chan, Jasper Fuk-Woo; To, Kelvin Kai-Wang; Zhou, Jie; Yuen, Kwok-Yung.

J Infect Dis; 221(4): 647-659, 2020 02 03.

Artículo en Inglés | MEDLINE | ID: mdl-31562757

5.

Attenuated Interferon and Proinflammatory Response in SARS-CoV-2-Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation.

Yang, Dong; Chu, Hin; Hou, Yuxin; Chai, Yue; Shuai, Huiping; Lee, Andrew Chak-Yiu; Zhang, Xi; Wang, Yixin; Hu, Bingjie; Huang, Xiner; Yuen, Terrence Tsz-Tai; Cai, Jian-Piao; Zhou, Jie; Yuan, Shuofeng; Zhang, Anna Jinxia; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung.

J Infect Dis; 222(5): 734-745, 2020 08 04.

Artículo en Inglés | MEDLINE | ID: mdl-32563187

6.

Co-infection by severe acute respiratory syndrome coronavirus 2 and influenza A(H1N1)pdm09 virus enhances the severity of pneumonia in golden Syrian hamsters.

Zhang, Anna Jinxia; Lee, Andrew Chak-Yiu; Chan, Jasper Fuk-Woo; Liu, Feifei; Li, Can; Chen, Yanxia; Chu, Hin; Lau, Siu-Ying; Wang, Pui; Chan, Chris Chung-Sing; Poon, Vincent Kwok-Man; Yuan, Shuofeng; To, Kelvin Kai-Wang; Chen, Honglin; Yuen, Kwok-Yung.

Clin Infect Dis; 2020 Nov 20.

Artículo en Inglés | MEDLINE | ID: mdl-33216851

7.

SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters.

Zhang, Anna Jinxia; Lee, Andrew Chak-Yiu; Chu, Hin; Chan, Jasper Fuk-Woo; Fan, Zhimeng; Li, Can; Liu, Feifei; Chen, Yanxia; Yuan, Shuofeng; Poon, Vincent Kwok-Man; Chan, Chris Chung-Sing; Cai, Jian-Piao; Wu, Kenneth Lap-Kei; Sridhar, Siddharth; Chan, Ying-Shing; Yuen, Kwok-Yung.

Clin Infect Dis; 2020 Jul 15.

Artículo en Inglés | MEDLINE | ID: mdl-32667973

8.

Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility.

Chan, Jasper Fuk-Woo; Zhang, Anna Jinxia; Yuan, Shuofeng; Poon, Vincent Kwok-Man; Chan, Chris Chung-Sing; Lee, Andrew Chak-Yiu; Chan, Wan-Mui; Fan, Zhimeng; Tsoi, Hoi-Wah; Wen, Lei; Liang, Ronghui; Cao, Jianli; Chen, Yanxia; Tang, Kaiming; Luo, Cuiting; Cai, Jian-Piao; Kok, Kin-Hang; Chu, Hin; Chan, Kwok-Hung; Sridhar, Siddharth; Chen, Zhiwei; Chen, Honglin; To, Kelvin Kai-Wang; Yuen, Kwok-Yung.

Clin Infect Dis; 71(9): 2428-2446, 2020 12 03.

Artículo en Inglés | MEDLINE | ID: mdl-32215622

9.

Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19).

Chan, Jasper Fuk-Woo; Yuan, Shuofeng; Zhang, Anna Jinxia; Poon, Vincent Kwok-Man; Chan, Chris Chung-Sing; Lee, Andrew Chak-Yiu; Fan, Zhimeng; Li, Can; Liang, Ronghui; Cao, Jianli; Tang, Kaiming; Luo, Cuiting; Cheng, Vincent Chi-Chung; Cai, Jian-Piao; Chu, Hin; Chan, Kwok-Hung; To, Kelvin Kai-Wang; Sridhar, Siddharth; Yuen, Kwok-Yung.

Clin Infect Dis; 71(16): 2139-2149, 2020 11 19.

Artículo en Inglés | MEDLINE | ID: mdl-32472679

10.

Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.

Chu, Hin; Chan, Jasper Fuk-Woo; Wang, Yixin; Yuen, Terrence Tsz-Tai; Chai, Yue; Hou, Yuxin; Shuai, Huiping; Yang, Dong; Hu, Bingjie; Huang, Xiner; Zhang, Xi; Cai, Jian-Piao; Zhou, Jie; Yuan, Shuofeng; Kok, Kin-Hang; To, Kelvin Kai-Wang; Chan, Ivy Hau-Yee; Zhang, Anna Jinxia; Sit, Ko-Yung; Au, Wing-Kuk; Yuen, Kwok-Yung.

Clin Infect Dis; 71(6): 1400-1409, 2020 09 12.

Artículo en Inglés | MEDLINE | ID: mdl-32270184

11.

Suppression of SARS-CoV-2 infection in ex-vivo human lung tissues by targeting class III phosphoinositide 3-kinase.

Yuen, Chun-Kit; Wong, Wan-Man; Mak, Long-Fung; Wang, Xiaohui; Chu, Hin; Yuen, Kwok-Yung; Kok, Kin-Hang.

J Med Virol; 2020 Oct 07.

Artículo en Inglés | MEDLINE | ID: mdl-33026649

12.

Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system.

Yuan, Shuofeng; Chan, Jasper F W; Chik, Kenn K H; Chan, Chris C Y; Tsang, Jessica O L; Liang, Ronghui; Cao, Jianli; Tang, Kaiming; Chen, Lin-Lei; Wen, Kun; Cai, Jian-Piao; Ye, Zi-Wei; Lu, Gang; Chu, Hin; Jin, Dong-Yan; Yuen, Kwok-Yung.

Pharmacol Res; 159: 104960, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32473310

13.

Effects of rhythmic auditory stimulation on upper-limb movement speed in patients with schizophrenia spectrum disorders.

Wang, Shu-Mei; Lin, Chung-Ying; Tse, Tracy Ho-Yan; Chu, Hin-Lun; Liu, Cheong-Ho; Ng, Tsz-Ho; Tse, Chun-Kwok; Wong, Wai-Man; Chan, Sunny Ho-Wan.

Eur Arch Psychiatry Clin Neurosci; 2020 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-32940786

14.

Durable infrared optical coatings based on pulsed DC-sputtering of hydrogenated amorphous carbon (a-C:H).

Gibson, Des; Song, Shigeng; Fleming, Lewis; Ahmadzadeh, Sam; Chu, Hin On; Sproules, Stephen; Swindell, Ryan; Zhang, Xiaoling; Navabpour, Parnia; Clark, Caspar; Bailey, Mark.

Appl Opt; 59(9): 2731-2738, 2020 Mar 20.

Artículo en Inglés | MEDLINE | ID: mdl-32225822

15.

Low-cost hyper-spectral imaging system using a linear variable bandpass filter for agritech applications.

Song, Shigeng; Gibson, Des; Ahmadzadeh, Sam; Chu, Hin On; Warden, Barry; Overend, Russell; Macfarlane, Fraser; Murray, Paul; Marshall, Stephen; Aitkenhead, Matt; Bienkowski, Damian; Allison, Russell.

Appl Opt; 59(5): A167-A175, 2020 Feb 10.

Artículo en Inglés | MEDLINE | ID: mdl-32225370

16.

Prostaglandin E2-Mediated Impairment of Innate Immune Response to A(H1N1)pdm09 Infection in Diet-Induced Obese Mice Could Be Restored by Paracetamol.

Zhang, Anna J X; Zhu, Houshun; Chen, Yanxia; Li, Chuangen; Li, Can; Chu, Hin; Gozali, Leonardi; Lee, Andrew C Y; To, Kelvin K W; Hung, Ivan F N; Yuen, Kwok-Yung.

J Infect Dis; 219(5): 795-807, 2019 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-30202973

17.

Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells.

Chu, Hin; Chan, Che-Man; Zhang, Xi; Wang, Yixin; Yuan, Shuofeng; Zhou, Jie; Au-Yeung, Rex Kwok-Him; Sze, Kong-Hung; Yang, Dong; Shuai, Huiping; Hou, Yuxin; Li, Cun; Zhao, Xiaoyu; Poon, Vincent Kwok-Man; Leung, Sze Pui; Yeung, Man-Lung; Yan, Jinghua; Lu, Guangwen; Jin, Dong-Yan; Gao, George Fu; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung.

J Biol Chem; 293(30): 11709-11726, 2018 07 27.

Artículo en Inglés | MEDLINE | ID: mdl-29887526

18.

Lipidomic Profiling Reveals Significant Perturbations of Intracellular Lipid Homeostasis in Enterovirus-Infected Cells.

Yan, Bingpeng; Zou, Zijiao; Chu, Hin; Chan, Gabriella; Tsang, Jessica Oi-Ling; Lai, Pok-Man; Yuan, Shuofeng; Yip, Cyril Chik-Yan; Yin, Feifei; Kao, Richard Yi-Tsun; Sze, Kong-Hung; Lau, Susanna Kar-Pui; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung.

Int J Mol Sci; 20(23)2019 Nov 26.

Artículo en Inglés | MEDLINE | ID: mdl-31779252

19.

Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy.

Zhu, Zheng; Chu, Hin; Wen, Lei; Yuan, Shuofeng; Chik, Kenn Ka-Heng; Yuen, Terrence Tsz-Tai; Yip, Cyril Chik-Yan; Wang, Dong; Zhou, Jie; Yin, Feifei; Jin, Dong-Yan; Kok, Kin-Hang; Yuen, Kwok-Yung; Chan, Jasper Fuk-Woo.

Int J Mol Sci; 20(2)2019 Jan 17.

Artículo en Inglés | MEDLINE | ID: mdl-30658479

20.

A tyrosine-based motif in the HIV-1 envelope glycoprotein tail mediates cell-type- and Rab11-FIP1C-dependent incorporation into virions.

Qi, Mingli; Chu, Hin; Chen, Xuemin; Choi, Junghwa; Wen, Xiaoyun; Hammonds, Jason; Ding, Lingmei; Hunter, Eric; Spearman, Paul.

Proc Natl Acad Sci U S A; 112(24): 7575-80, 2015 Jun 16.

Artículo en Inglés | MEDLINE | ID: mdl-26034275

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