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1.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Wrapp, Daniel; De Vlieger, Dorien; Corbett, Kizzmekia S; Torres, Gretel M; Wang, Nianshuang; Van Breedam, Wander; Roose, Kenny; van Schie, Loes; Hoffmann, Markus; Pöhlmann, Stefan; Graham, Barney S; Callewaert, Nico; Schepens, Bert; Saelens, Xavier; McLellan, Jason S.

Cell; 181(5): 1004-1015.e15, 2020 05 28.

Artículo en Inglés | MEDLINE | ID: mdl-32375025

2.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Wrapp, Daniel; De Vlieger, Dorien; Corbett, Kizzmekia S; Torres, Gretel M; Wang, Nianshuang; Van Breedam, Wander; Roose, Kenny; van Schie, Loes; Hoffmann, Markus; Pöhlmann, Stefan; Graham, Barney S; Callewaert, Nico; Schepens, Bert; Saelens, Xavier; McLellan, Jason S.

Cell; 181(6): 1436-1441, 2020 Jun 11.

Artículo en Inglés | MEDLINE | ID: mdl-32531248

3.

Chemical-controlled Activation of Antiviral Myxovirus Resistance Protein 1.

Verhelst, Judith; Van Hoecke, Lien; Spitaels, Jan; De Vlieger, Dorien; Kolpe, Annasaheb; Saelens, Xavier.

J Biol Chem; 292(6): 2226-2236, 2017 02 10.

Artículo en Inglés | MEDLINE | ID: mdl-28011636

4.

Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses.

Verhelst, Judith; Spitaels, Jan; Nürnberger, Cindy; De Vlieger, Dorien; Ysenbaert, Tine; Staeheli, Peter; Fiers, Walter; Saelens, Xavier.

J Virol; 89(21): 10879-90, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26292322

5.

mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice.

Van Hoecke, Lien; Verbeke, Rein; De Vlieger, Dorien; Dewitte, Heleen; Roose, Kenny; Van Nevel, Sharon; Krysko, Olga; Bachert, Claus; Schepens, Bert; Lentacker, Ine; Saelens, Xavier.

Mol Ther Nucleic Acids; 20: 777-787, 2020 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-32438313

6.

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters.

Boudewijns, Robbert; Thibaut, Hendrik Jan; Kaptein, Suzanne J F; Li, Rong; Vergote, Valentijn; Seldeslachts, Laura; Van Weyenbergh, Johan; De Keyzer, Carolien; Bervoets, Lindsey; Sharma, Sapna; Liesenborghs, Laurens; Ma, Ji; Jansen, Sander; Van Looveren, Dominique; Vercruysse, Thomas; Wang, Xinyu; Jochmans, Dirk; Martens, Erik; Roose, Kenny; De Vlieger, Dorien; Schepens, Bert; Van Buyten, Tina; Jacobs, Sofie; Liu, Yanan; Martí-Carreras, Joan; Vanmechelen, Bert; Wawina-Bokalanga, Tony; Delang, Leen; Rocha-Pereira, Joana; Coelmont, Lotte; Chiu, Winston; Leyssen, Pieter; Heylen, Elisabeth; Schols, Dominique; Wang, Lanjiao; Close, Lila; Matthijnssens, Jelle; Van Ranst, Marc; Compernolle, Veerle; Schramm, Georg; Van Laere, Koen; Saelens, Xavier; Callewaert, Nico; Opdenakker, Ghislain; Maes, Piet; Weynand, Birgit; Cawthorne, Christopher; Vande Velde, Greetje; Wang, Zhongde; Neyts, Johan.

Nat Commun; 11(1): 5838, 2020 11 17.

Artículo en Inglés | MEDLINE | ID: mdl-33203860

7.

Selective Engagement of FcÎ³RIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection.

De Vlieger, Dorien; Hoffmann, Katja; Van Molle, Inge; Nerinckx, Wim; Van Hoecke, Lien; Ballegeer, Marlies; Creytens, Sarah; Remaut, Han; Hengel, Hartmut; Schepens, Bert; Saelens, Xavier.

Front Immunol; 10: 2920, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31921179

8.

Vaccine options for influenza: thinking small.

Schepens, Bert; De Vlieger, Dorien; Saelens, Xavier.

Curr Opin Immunol; 53: 22-29, 2018 08.

Artículo en Inglés | MEDLINE | ID: mdl-29631195

9.

Single-Domain Antibodies and Their Formatting to Combat Viral Infections.

De Vlieger, Dorien; Ballegeer, Marlies; Rossey, Iebe; Schepens, Bert; Saelens, Xavier.

Antibodies (Basel); 8(1)2018 Dec 20.

Artículo en Inglés | MEDLINE | ID: mdl-31544807

10.

Co-immunoprecipitation of the Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein.

Verhelst, Judith; De Vlieger, Dorien; Saelens, Xavier.

J Vis Exp; (98)2015 Apr 21.

Artículo en Inglés | MEDLINE | ID: mdl-25938860

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Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Chemical-controlled Activation of Antiviral Myxovirus Resistance Protein 1.

Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses.

mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice.

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters.

Selective Engagement of FcÎ³RIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection.

Vaccine options for influenza: thinking small.

Single-Domain Antibodies and Their Formatting to Combat Viral Infections.

Co-immunoprecipitation of the Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein.