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1.

Snatch-and-Grab Inhibitors to Fight the Flu.

García-Sastre, Adolfo.

Cell; 177(6): 1367, 2019 05 30.

Artículo en Inglés | MEDLINE | ID: mdl-31150614

2.

A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.

Bangaru, Sandhya; Lang, Shanshan; Schotsaert, Michael; Vanderven, Hillary A; Zhu, Xueyong; Kose, Nurgun; Bombardi, Robin; Finn, Jessica A; Kent, Stephen J; Gilchuk, Pavlo; Gilchuk, Iuliia; Turner, Hannah L; García-Sastre, Adolfo; Li, Sheng; Ward, Andrew B; Wilson, Ian A; Crowe, James E.

Cell; 177(5): 1136-1152.e18, 2019 05 16.

Artículo en Inglés | MEDLINE | ID: mdl-31100268

3.

Transcription Elongation Can Affect Genome 3D Structure.

Heinz, Sven; Texari, Lorane; Hayes, Michael G B; Urbanowski, Matthew; Chang, Max W; Givarkes, Ninvita; Rialdi, Alexander; White, Kris M; Albrecht, Randy A; Pache, Lars; Marazzi, Ivan; García-Sastre, Adolfo; Shaw, Megan L; Benner, Christopher.

Cell; 174(6): 1522-1536.e22, 2018 09 06.

Artículo en Inglés | MEDLINE | ID: mdl-30146161

4.

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.

Shah, Priya S; Link, Nichole; Jang, Gwendolyn M; Sharp, Phillip P; Zhu, Tongtong; Swaney, Danielle L; Johnson, Jeffrey R; Von Dollen, John; Ramage, Holly R; Satkamp, Laura; Newton, Billy; Hüttenhain, Ruth; Petit, Marine J; Baum, Tierney; Everitt, Amanda; Laufman, Orly; Tassetto, Michel; Shales, Michael; Stevenson, Erica; Iglesias, Gabriel N; Shokat, Leila; Tripathi, Shashank; Balasubramaniam, Vinod; Webb, Laurence G; Aguirre, Sebastian; Willsey, A Jeremy; Garcia-Sastre, Adolfo; Pollard, Katherine S; Cherry, Sara; Gamarnik, Andrea V; Marazzi, Ivan; Taunton, Jack; Fernandez-Sesma, Ana; Bellen, Hugo J; Andino, Raul; Krogan, Nevan J.

Cell; 175(7): 1931-1945.e18, 2018 12 13.

Artículo en Inglés | MEDLINE | ID: mdl-30550790

5.

The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity.

Rialdi, Alexander; Hultquist, Judd; Jimenez-Morales, David; Peralta, Zuleyma; Campisi, Laura; Fenouil, Romain; Moshkina, Natasha; Wang, Zhen Zhen; Laffleur, Brice; Kaake, Robyn M; McGregor, Michael J; Haas, Kelsey; Pefanis, Evangelos; Albrecht, Randy A; Pache, Lars; Chanda, Sumit; Jen, Joanna; Ochando, Jordi; Byun, Minji; Basu, Uttiya; García-Sastre, Adolfo; Krogan, Nevan; van Bakel, Harm; Marazzi, Ivan.

Cell; 169(4): 679-692.e14, 2017 05 04.

Artículo en Inglés | MEDLINE | ID: mdl-28475896

6.

PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.

Yoh, Sunnie M; Schneider, Monika; Seifried, Janna; Soonthornvacharin, Stephen; Akleh, Rana E; Olivieri, Kevin C; De Jesus, Paul D; Ruan, Chunhai; de Castro, Elisa; Ruiz, Pedro A; Germanaud, David; des Portes, Vincent; García-Sastre, Adolfo; König, Renate; Chanda, Sumit K.

Cell; 161(6): 1293-1305, 2015 Jun 04.

Artículo en Inglés | MEDLINE | ID: mdl-26046437

7.

Defining the antibody cross-reactome directed against the influenza virus surface glycoproteins.

Nachbagauer, Raffael; Choi, Angela; Hirsh, Ariana; Margine, Irina; Iida, Sayaka; Barrera, Aldo; Ferres, Marcela; Albrecht, Randy A; García-Sastre, Adolfo; Bouvier, Nicole M; Ito, Kimihito; Medina, Rafael A; Palese, Peter; Krammer, Florian.

Nat Immunol; 18(4): 464-473, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-28192418

8.

Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses.

Guthmiller, Jenna J; Lan, Linda Yu-Ling; Fernández-Quintero, Monica L; Han, Julianna; Utset, Henry A; Bitar, Dalia J; Hamel, Natalie J; Stovicek, Olivia; Li, Lei; Tepora, Micah; Henry, Carole; Neu, Karlynn E; Dugan, Haley L; Borowska, Marta T; Chen, Yao-Qing; Liu, Sean T H; Stamper, Christopher T; Zheng, Nai-Ying; Huang, Min; Palm, Anna-Karin E; García-Sastre, Adolfo; Nachbagauer, Raffael; Palese, Peter; Coughlan, Lynda; Krammer, Florian; Ward, Andrew B; Liedl, Klaus R; Wilson, Patrick C.

Immunity; 2020 Oct 17.

Artículo en Inglés | MEDLINE | ID: mdl-33096040

9.

Dengue Virus Immunity Increases Zika Virus-Induced Damage during Pregnancy.

Brown, Julia A; Singh, Gursewak; Acklin, Joshua A; Lee, Silviana; Duehr, James E; Chokola, Anupa N; Frere, Justin J; Hoffman, Kevin W; Foster, Gregory A; Krysztof, David; Cadagan, Richard; Jacobs, Adam R; Stramer, Susan L; Krammer, Florian; García-Sastre, Adolfo; Lim, Jean K.

Immunity; 50(3): 751-762.e5, 2019 03 19.

Artículo en Inglés | MEDLINE | ID: mdl-30737148

10.

Lessons from lipids in the fight against influenza.

García-Sastre, Adolfo.

Cell; 154(1): 22-3, 2013 Jul 03.

Artículo en Inglés | MEDLINE | ID: mdl-23827671

11.

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.

Riva, Laura; Yuan, Shuofeng; Yin, Xin; Martin-Sancho, Laura; Matsunaga, Naoko; Pache, Lars; Burgstaller-Muehlbacher, Sebastian; De Jesus, Paul D; Teriete, Peter; Hull, Mitchell V; Chang, Max W; Chan, Jasper Fuk-Woo; Cao, Jianli; Poon, Vincent Kwok-Man; Herbert, Kristina M; Cheng, Kuoyuan; Nguyen, Tu-Trinh H; Rubanov, Andrey; Pu, Yuan; Nguyen, Courtney; Choi, Angela; Rathnasinghe, Raveen; Schotsaert, Michael; Miorin, Lisa; Dejosez, Marion; Zwaka, Thomas P; Sit, Ko-Yung; Martinez-Sobrido, Luis; Liu, Wen-Chun; White, Kris M; Chapman, Mackenzie E; Lendy, Emma K; Glynne, Richard J; Albrecht, Randy; Ruppin, Eytan; Mesecar, Andrew D; Johnson, Jeffrey R; Benner, Christopher; Sun, Ren; Schultz, Peter G; Su, Andrew I; García-Sastre, Adolfo; Chatterjee, Arnab K; Yuen, Kwok-Yung; Chanda, Sumit K.

Nature; 586(7827): 113-119, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32707573

12.

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.

Heaton, Nicholas S; Moshkina, Natasha; Fenouil, Romain; Gardner, Thomas J; Aguirre, Sebastian; Shah, Priya S; Zhao, Nan; Manganaro, Lara; Hultquist, Judd F; Noel, Justine; Sachs, David; Hamilton, Jennifer; Leon, Paul E; Chawdury, Amit; Tripathi, Shashank; Melegari, Camilla; Campisi, Laura; Hai, Rong; Metreveli, Giorgi; Gamarnik, Andrea V; García-Sastre, Adolfo; Greenbaum, Benjamin; Simon, Viviana; Fernandez-Sesma, Ana; Krogan, Nevan J; Mulder, Lubbertus C F; van Bakel, Harm; Tortorella, Domenico; Taunton, Jack; Palese, Peter; Marazzi, Ivan.

Immunity; 44(1): 46-58, 2016 Jan 19.

Artículo en Inglés | MEDLINE | ID: mdl-26789921

13.

MHC class II proteins mediate cross-species entry of bat influenza viruses.

Karakus, Umut; Thamamongood, Thiprampai; Ciminski, Kevin; Ran, Wei; Günther, Sira C; Pohl, Marie O; Eletto, Davide; Jeney, Csaba; Hoffmann, Donata; Reiche, Sven; Schinköthe, Jan; Ulrich, Reiner; Wiener, Julius; Hayes, Michael G B; Chang, Max W; Hunziker, Annika; Yángüez, Emilio; Aydillo, Teresa; Krammer, Florian; Oderbolz, Josua; Meier, Matthias; Oxenius, Annette; Halenius, Anne; Zimmer, Gert; Benner, Christopher; Hale, Benjamin G; García-Sastre, Adolfo; Beer, Martin; Schwemmle, Martin; Stertz, Silke.

Nature; 567(7746): 109-112, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30787439

14.

Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases.

Gorenshteyn, Dmitriy; Zaslavsky, Elena; Fribourg, Miguel; Park, Christopher Y; Wong, Aaron K; Tadych, Alicja; Hartmann, Boris M; Albrecht, Randy A; García-Sastre, Adolfo; Kleinstein, Steven H; Troyanskaya, Olga G; Sealfon, Stuart C.

Immunity; 43(3): 605-14, 2015 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-26362267

15.

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKÎµ kinase-mediated antiviral response.

Rajsbaum, Ricardo; Versteeg, Gijs A; Schmid, Sonja; Maestre, Ana M; Belicha-Villanueva, Alan; Martínez-Romero, Carles; Patel, Jenish R; Morrison, Juliet; Pisanelli, Giuseppe; Miorin, Lisa; Laurent-Rolle, Maudry; Moulton, Hong M; Stein, David A; Fernandez-Sesma, Ana; tenOever, Benjamin R; García-Sastre, Adolfo.

Immunity; 40(6): 880-95, 2014 Jun 19.

Artículo en Inglés | MEDLINE | ID: mdl-24882218

16.

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.

Miorin, Lisa; Kehrer, Thomas; Sanchez-Aparicio, Maria Teresa; Zhang, Ke; Cohen, Phillip; Patel, Roosheel S; Cupic, Anastasija; Makio, Tadashi; Mei, Menghan; Moreno, Elena; Danziger, Oded; White, Kris M; Rathnasinghe, Raveen; Uccellini, Melissa; Gao, Shengyan; Aydillo, Teresa; Mena, Ignacio; Yin, Xin; Martin-Sancho, Laura; Krogan, Nevan J; Chanda, Sumit K; Schotsaert, Michael; Wozniak, Richard W; Ren, Yi; Rosenberg, Brad R; Fontoura, Beatriz M A; García-Sastre, Adolfo.

Proc Natl Acad Sci U S A; 117(45): 28344-28354, 2020 11 10.

Artículo en Inglés | MEDLINE | ID: mdl-33097660

17.

Chemical intervention of influenza virus mRNA nuclear export.

Esparza, Matthew; Mor, Amir; Niederstrasser, Hanspeter; White, Kris; White, Alexander; Zhang, Ke; Gao, Shengyan; Wang, Juan; Liang, Jue; Sho, Sei; Sakthivel, Ramanavelan; Sathe, Adwait A; Xing, Chao; Muñoz-Moreno, Raquel; Shay, Jerry W; García-Sastre, Adolfo; Ready, Joseph; Posner, Bruce; Fontoura, Beatriz M A.

PLoS Pathog; 16(4): e1008407, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32240278

18.

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.

Versteeg, Gijs A; Rajsbaum, Ricardo; Sánchez-Aparicio, Maria Teresa; Maestre, Ana M; Valdiviezo, Julio; Shi, Mude; Inn, Kyung-Soo; Fernandez-Sesma, Ana; Jung, Jae; García-Sastre, Adolfo.

Immunity; 38(2): 384-98, 2013 Feb 21.

Artículo en Inglés | MEDLINE | ID: mdl-23438823

19.

Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes.

Hashimoto, Daigo; Chow, Andrew; Noizat, Clara; Teo, Pearline; Beasley, Mary Beth; Leboeuf, Marylene; Becker, Christian D; See, Peter; Price, Jeremy; Lucas, Daniel; Greter, Melanie; Mortha, Arthur; Boyer, Scott W; Forsberg, E Camilla; Tanaka, Masato; van Rooijen, Nico; García-Sastre, Adolfo; Stanley, E Richard; Ginhoux, Florent; Frenette, Paul S; Merad, Miriam.

Immunity; 38(4): 792-804, 2013 Apr 18.

Artículo en Inglés | MEDLINE | ID: mdl-23601688

20.

A Genome-Wide CRISPR-Cas9 Screen Reveals the Requirement of Host Cell Sulfation for Schmallenberg Virus Infection.

Thamamongood, Thiprampai; Aebischer, Andrea; Wagner, Valentina; Chang, Max W; Elling, Roland; Benner, Christopher; García-Sastre, Adolfo; Kochs, Georg; Beer, Martin; Schwemmle, Martin.

J Virol; 94(17)2020 08 17.

Artículo en Inglés | MEDLINE | ID: mdl-32522852

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