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1.

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

Hoffmann, Markus; Kleine-Weber, Hannah; Schroeder, Simon; Krüger, Nadine; Herrler, Tanja; Erichsen, Sandra; Schiergens, Tobias S; Herrler, Georg; Wu, Nai-Huei; Nitsche, Andreas; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan.

Cell; 181(2): 271-280.e8, 2020 04 16.

Artículo en Inglés | MEDLINE | ID: covidwho-4561

2.

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

Hoffmann, Markus; Kleine-Weber, Hannah; Schroeder, Simon; Krüger, Nadine; Herrler, Tanja; Erichsen, Sandra; Schiergens, Tobias S; Herrler, Georg; Wu, Nai-Huei; Nitsche, Andreas; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan.

Cell; 181(2): 271-280.e8, 2020 04 16.

Artículo en Inglés | MEDLINE | ID: mdl-32142651

3.

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells.

Hoffmann, Markus; Kleine-Weber, Hannah; Pöhlmann, Stefan.

Mol Cell; 78(4): 779-784.e5, 2020 05 21.

Artículo en Inglés | MEDLINE | ID: covidwho-88548

4.

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells.

Hoffmann, Markus; Kleine-Weber, Hannah; Pöhlmann, Stefan.

Mol Cell; 78(4): 779-784.e5, 2020 05 21.

Artículo en Inglés | MEDLINE | ID: mdl-32362314

5.

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.

Hoffmann, Markus; Mösbauer, Kirstin; Hofmann-Winkler, Heike; Kaul, Artur; Kleine-Weber, Hannah; Krüger, Nadine; Gassen, Nils C; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan.

Nature; 585(7826): 588-590, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32698190

6.

Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization.

Kleine-Weber, Hannah; Elzayat, Mahmoud Tarek; Wang, Lingshu; Graham, Barney S; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan; Hoffmann, Markus.

J Virol; 93(2)2019 01 15.

Artículo en Inglés | MEDLINE | ID: mdl-30404801

7.

Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19.

Hoffmann, Markus; Schroeder, Simon; Kleine-Weber, Hannah; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan.

Antimicrob Agents Chemother; 64(6)2020 05 21.

Artículo en Inglés | MEDLINE | ID: covidwho-88701

8.

Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19.

Hoffmann, Markus; Schroeder, Simon; Kleine-Weber, Hannah; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan.

Antimicrob Agents Chemother; 64(6)2020 05 21.

Artículo en Inglés | MEDLINE | ID: mdl-32312781

9.

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus.

Kleine-Weber, Hannah; Schroeder, Simon; Krüger, Nadine; Prokscha, Alexander; Naim, Hassan Y; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan; Hoffmann, Markus.

Emerg Microbes Infect; 9(1): 155-168, 2020.

Artículo en Inglés | MEDLINE | ID: covidwho-326251

10.

Spike proteins of novel MERS-coronavirus isolates from North- and West-African dromedary camels mediate robust viral entry into human target cells.

Kleine-Weber, Hannah; Pöhlmann, Stefan; Hoffmann, Markus.

Virology; 535: 261-265, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-31357164

11.

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus.

Kleine-Weber, Hannah; Schroeder, Simon; Krüger, Nadine; Prokscha, Alexander; Naim, Hassan Y; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan; Hoffmann, Markus.

Emerg Microbes Infect; 9(1): 155-168, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-31964246

12.

Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods.

Bosnjak, Berislav; Stein, Saskia Catherina; Willenzon, Stefanie; Cordes, Anne Katrin; Puppe, Wolfram; Bernhardt, Günter; Ravens, Inga; Ritter, Christiane; Schultze-Florey, Christian R; Gödecke, Nina; Martens, Jörg; Kleine-Weber, Hannah; Hoffmann, Markus; Cossmann, Anne; Yilmaz, Mustafa; Pink, Isabelle; Hoeper, Marius M; Behrens, Georg M N; Pöhlmann, Stefan; Blasczyk, Rainer; Schulz, Thomas F; Förster, Reinhold.

Cell Mol Immunol; 2020 Nov 02.

Artículo en Inglés | MEDLINE | ID: mdl-33139905

13.

LY6E impairs coronavirus fusion and confers immune control of viral disease.

Pfaender, Stephanie; Mar, Katrina B; Michailidis, Eleftherios; Kratzel, Annika; Boys, Ian N; V'kovski, Philip; Fan, Wenchun; Kelly, Jenna N; Hirt, Dagny; Ebert, Nadine; Stalder, Hanspeter; Kleine-Weber, Hannah; Hoffmann, Markus; Hoffmann, Hans-Heinrich; Saeed, Mohsan; Dijkman, Ronald; Steinmann, Eike; Wight-Carter, Mary; McDougal, Matthew B; Hanners, Natasha W; Pöhlmann, Stefan; Gallagher, Tom; Todt, Daniel; Zimmer, Gert; Rice, Charles M; Schoggins, John W; Thiel, Volker.

Nat Microbiol; 5(11): 1330-1339, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-32704094

14.

Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein.

Kleine-Weber, Hannah; Elzayat, Mahmoud Tarek; Hoffmann, Markus; Pöhlmann, Stefan.

Sci Rep; 8(1): 16597, 2018 11 09.

Artículo en Inglés | MEDLINE | ID: mdl-30413791

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells.

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells.

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.

Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization.

Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19.

Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19.

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus.

Spike proteins of novel MERS-coronavirus isolates from North- and West-African dromedary camels mediate robust viral entry into human target cells.

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus.

Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods.

LY6E impairs coronavirus fusion and confers immune control of viral disease.

Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein.