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1.

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

Hoffmann, Markus; Kleine-Weber, Hannah; Schroeder, Simon; Krüger, Nadine; Herrler, Tanja; Erichsen, Sandra; Schiergens, Tobias S; Herrler, Georg; Wu, Nai-Huei; Nitsche, Andreas; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan.

Cell; 181(2): 271-280.e8, 2020 04 16.

Artículo en Inglés | MEDLINE | ID: covidwho-4561

2.

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

Hoffmann, Markus; Kleine-Weber, Hannah; Schroeder, Simon; Krüger, Nadine; Herrler, Tanja; Erichsen, Sandra; Schiergens, Tobias S; Herrler, Georg; Wu, Nai-Huei; Nitsche, Andreas; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan.

Cell; 181(2): 271-280.e8, 2020 04 16.

Artículo en Inglés | MEDLINE | ID: mdl-32142651

3.

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.

Hoffmann, Markus; Mösbauer, Kirstin; Hofmann-Winkler, Heike; Kaul, Artur; Kleine-Weber, Hannah; Krüger, Nadine; Gassen, Nils C; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan.

Nature; 585(7826): 588-590, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32698190

4.

The Amino Acid at Position 8 of the Proteolytic Cleavage Site of the Mumps Virus Fusion Protein Affects Viral Proteolysis and Fusogenicity.

Hüttl, Sarah; Hoffmann, Markus; Steinmetzer, Torsten; Sauder, Christian; Krüger, Nadine.

J Virol; 94(22)2020 10 27.

Artículo en Inglés | MEDLINE | ID: mdl-32907974

5.

Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells.

Hoffmann, Markus; Nehlmeier, Inga; Brinkmann, Constantin; Krähling, Verena; Behner, Laura; Moldenhauer, Anna-Sophie; Krüger, Nadine; Nehls, Julia; Schindler, Michael; Hoenen, Thomas; Maisner, Andrea; Becker, Stephan; Pöhlmann, Stefan.

J Virol; 93(3)2019 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-30429347

6.

Human Infections by Non-Rodent-Associated Hantaviruses in Africa.

Heinemann, Patrick; Tia, Mélanie; Alabi, Abraham; Anon, Jean-Claude; Auste, Brita; Essbauer, Sandra; Gnionsahe, Apollinaire; Kigninlman, Holo; Klempa, Boris; Kraef, Christian; Kruger, Nadine; Leendertz, Fabian H; Ndhatz-Sanogo, Méliane; Schaumburg, Frieder; Witkowski, Peter T; Akoua-Koffi, Chantal G; Kruger, Detlev H.

J Infect Dis; 214(10): 1507-1511, 2016 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-27601619

7.

Recombinant mumps viruses expressing the batMuV fusion glycoprotein are highly fusion active and neurovirulent.

Krüger, Nadine; Sauder, Christian; Hoffmann, Markus; Örvell, Claes; Drexler, Jan Felix; Rubin, Steven; Herrler, Georg.

J Gen Virol; 97(11): 2837-2848, 2016 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-27590163

8.

Functional properties and genetic relatedness of the fusion and hemagglutinin-neuraminidase proteins of a mumps virus-like bat virus.

Krüger, Nadine; Hoffmann, Markus; Drexler, Jan Felix; Müller, Marcel Alexander; Corman, Victor Max; Sauder, Christian; Rubin, Steven; He, Biao; Örvell, Claes; Drosten, Christian; Herrler, Georg.

J Virol; 89(8): 4539-48, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25741010

9.

Attachment protein G of an African bat henipavirus is differentially restricted in chiropteran and nonchiropteran cells.

Krüger, Nadine; Hoffmann, Markus; Drexler, Jan Felix; Müller, Marcel Alexander; Corman, Victor Max; Drosten, Christian; Herrler, Georg.

J Virol; 88(20): 11973-80, 2014 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-25100832

10.

Characterization of African bat henipavirus GH-M74a glycoproteins.

Weis, Michael; Behner, Laura; Hoffmann, Markus; Krüger, Nadine; Herrler, Georg; Drosten, Christian; Drexler, Jan Felix; Dietzel, Erik; Maisner, Andrea.

J Gen Virol; 95(Pt 3): 539-48, 2014 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-24296468

11.

Surface glycoproteins of an African henipavirus induce syncytium formation in a cell line derived from an African fruit bat, Hypsignathus monstrosus.

Krüger, Nadine; Hoffmann, Markus; Weis, Michael; Drexler, Jan Felix; Müller, Marcel Alexander; Winter, Christine; Corman, Victor Max; Gützkow, Tim; Drosten, Christian; Maisner, Andrea; Herrler, Georg.

J Virol; 87(24): 13889-91, 2013 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-24067951

12.

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus.

Kleine-Weber, Hannah; Schroeder, Simon; Krüger, Nadine; Prokscha, Alexander; Naim, Hassan Y; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan; Hoffmann, Markus.

Emerg Microbes Infect; 9(1): 155-168, 2020.

Artículo en Inglés | MEDLINE | ID: covidwho-326251

13.

Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins.

Plegge, Teresa; Spiegel, Martin; Krüger, Nadine; Nehlmeier, Inga; Winkler, Michael; González Hernández, Mariana; Pöhlmann, Stefan.

PLoS One; 14(4): e0214968, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-30973897

14.

Fusogenicity of the Ghana Virus (Henipavirus: Ghanaian bat henipavirus) Fusion Protein is Controlled by the Cytoplasmic Domain of the Attachment Glycoprotein.

Voigt, Kathleen; Hoffmann, Markus; Drexler, Jan Felix; Müller, Marcel Alexander; Drosten, Christian; Herrler, Georg; Krüger, Nadine.

Viruses; 11(9)2019 Aug 29.

Artículo en Inglés | MEDLINE | ID: mdl-31470664

15.

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus.

Kleine-Weber, Hannah; Schroeder, Simon; Krüger, Nadine; Prokscha, Alexander; Naim, Hassan Y; Müller, Marcel A; Drosten, Christian; Pöhlmann, Stefan; Hoffmann, Markus.

Emerg Microbes Infect; 9(1): 155-168, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-31964246

16.

The Sialic Acid Binding Activity of Human Parainfluenza Virus 3 and Mumps Virus Glycoproteins Enhances the Adherence of Group B Streptococci to HEp-2 Cells.

Tong, Jie; Fu, Yuguang; Meng, Fandan; Krüger, Nadine; Valentin-Weigand, Peter; Herrler, Georg.

Front Cell Infect Microbiol; 8: 280, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30175075

17.

Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus.

Krüger, Nadine; Sauder, Christian; Hüttl, Sarah; Papies, Jan; Voigt, Kathleen; Herrler, Georg; Hardes, Kornelia; Steinmetzer, Torsten; Örvell, Claes; Drexler, Jan Felix; Drosten, Christian; Rubin, Steven; Müller, Marcel Alexander; Hoffmann, Markus.

Cell Rep; 25(2): 312-320.e7, 2018 10 09.

Artículo en Inglés | MEDLINE | ID: mdl-30304672

18.

Association of mitochondria with spindle poles facilitates spindle alignment.

Krüger, Nadine; Tolic-Nørrelykke, Iva M.

Curr Biol; 18(15): R646-R647, 2008 Aug 05.

Artículo en Inglés | MEDLINE | ID: mdl-18682200

19.

Influence of sibutramine treatment on sympathetic vasomotor tone in obese subjects.

Heusser, Karsten; Tank, Jens; Diedrich, Andre; Engeli, Stefan; Klaua, Susanne; Krüger, Nadine; Strauss, Anke; Stoffels, Gritt; Luft, Friedrich C; Jordan, Jens.

Clin Pharmacol Ther; 79(5): 500-8, 2006 May.

Artículo en Inglés | MEDLINE | ID: mdl-16678551

20.

The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.

Hoffmann, Markus; Krüger, Nadine; Zmora, Pawel; Wrensch, Florian; Herrler, Georg; Pöhlmann, Stefan.

PLoS One; 11(3): e0152134, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-27028521

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.

The Amino Acid at Position 8 of the Proteolytic Cleavage Site of the Mumps Virus Fusion Protein Affects Viral Proteolysis and Fusogenicity.

Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells.

Human Infections by Non-Rodent-Associated Hantaviruses in Africa.

Recombinant mumps viruses expressing the batMuV fusion glycoprotein are highly fusion active and neurovirulent.

Functional properties and genetic relatedness of the fusion and hemagglutinin-neuraminidase proteins of a mumps virus-like bat virus.

Attachment protein G of an African bat henipavirus is differentially restricted in chiropteran and nonchiropteran cells.

Characterization of African bat henipavirus GH-M74a glycoproteins.

Surface glycoproteins of an African henipavirus induce syncytium formation in a cell line derived from an African fruit bat, Hypsignathus monstrosus.

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus.

Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins.

Fusogenicity of the Ghana Virus (Henipavirus: Ghanaian bat henipavirus) Fusion Protein is Controlled by the Cytoplasmic Domain of the Attachment Glycoprotein.

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus.

The Sialic Acid Binding Activity of Human Parainfluenza Virus 3 and Mumps Virus Glycoproteins Enhances the Adherence of Group B Streptococci to HEp-2 Cells.

Entry, Replication, Immune Evasion, and Neurotoxicity of Synthetically Engineered Bat-Borne Mumps Virus.

Association of mitochondria with spindle poles facilitates spindle alignment.

Influence of sibutramine treatment on sympathetic vasomotor tone in obese subjects.

The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.