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1.

Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus.

Stappers, Mark H T; Clark, Alexandra E; Aimanianda, Vishukumar; Bidula, Stefan; Reid, Delyth M; Asamaphan, Patawee; Hardison, Sarah E; Dambuza, Ivy M; Valsecchi, Isabel; Kerscher, Bernhard; Plato, Anthony; Wallace, Carol A; Yuecel, Raif; Hebecker, Betty; da Glória Teixeira Sousa, Maria; Cunha, Cristina; Liu, Yan; Feizi, Ten; Brakhage, Axel A; Kwon-Chung, Kyung J; Gow, Neil A R; Zanda, Matteo; Piras, Monica; Zanato, Chiara; Jaeger, Martin; Netea, Mihai G; van de Veerdonk, Frank L; Lacerda, João F; Campos, António; Carvalho, Agostinho; Willment, Janet A; Latgé, Jean-Paul; Brown, Gordon D.

Nature; 555(7696): 382-386, 2018 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-29489751

2.

Roles of Three Cryptococcus neoformans and Cryptococcus gattii Efflux Pump-Coding Genes in Response to Drug Treatment.

Chang, Miwha; Sionov, Edward; Khanal Lamichhane, Ami; Kwon-Chung, Kyung J; Chang, Yun C.

Antimicrob Agents Chemother; 62(4)2018 04.

Artículo en Inglés | MEDLINE | ID: mdl-29378705

3.

Cryptococcus gattii Capsule Blocks Surface Recognition Required for Dendritic Cell Maturation Independent of Internalization and Antigen Processing.

Huston, Shaunna M; Ngamskulrungroj, Popchai; Xiang, Richard F; Ogbomo, Henry; Stack, Danuta; Li, Shu Shun; Timm-McCann, Martina; Kyei, Stephen K; Oykhman, Paul; Kwon-Chung, Kyung J; Mody, Christopher H.

J Immunol; 196(3): 1259-71, 2016 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-26740109

4.

Fundamental niche prediction of the pathogenic yeasts Cryptococcus neoformans and Cryptococcus gattii in Europe.

Cogliati, Massimo; Puccianti, Erika; Montagna, Maria T; De Donno, Antonella; Susever, Serdar; Ergin, Cagri; Velegraki, Aristea; Ellabib, Mohamed S; Nardoni, Simona; Macci, Cristina; Trovato, Laura; Dipineto, Ludovico; Rickerts, Volker; Akcaglar, Sevim; Mlinaric-Missoni, Emilija; Bertout, Sebastien; Vencà, Ana C F; Sampaio, Ana C; Criseo, Giuseppe; Ranque, Stéphane; Çerikçioglu, Nilgün; Marchese, Anna; Vezzulli, Luigi; Ilkit, Macit; Desnos-Ollivier, Marie; Pasquale, Vincenzo; Polacheck, Itzhack; Scopa, Antonio; Meyer, Wieland; Ferreira-Paim, Kennio; Hagen, Ferry; Boekhout, Teun; Dromer, Françoise; Varma, Ashok; Kwon-Chung, Kyung J; Inácio, Joäo; Colom, Maria F.

Environ Microbiol; 19(10): 4318-4325, 2017 10.

Artículo en Inglés | MEDLINE | ID: mdl-28892309

5.

Type I IFN Induction via Poly-ICLC Protects Mice against Cryptococcosis.

Sionov, Edward; Mayer-Barber, Katrin D; Chang, Yun C; Kauffman, Keith D; Eckhaus, Michael A; Salazar, Andres M; Barber, Daniel L; Kwon-Chung, Kyung J.

PLoS Pathog; 11(8): e1005040, 2015 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-26252005

6.

Genetic Analysis Using an Isogenic Mating Pair of Aspergillus fumigatus Identifies Azole Resistance Genes and Lack of MAT Locus's Role in Virulence.

Losada, Liliana; Sugui, Janyce A; Eckhaus, Michael A; Chang, Yun C; Mounaud, Stephanie; Figat, Abigail; Joardar, Vinita; Pakala, Suman B; Pakala, Suchitra; Venepally, Pratap; Fedorova, Natalie; Nierman, William C; Kwon-Chung, Kyung J.

PLoS Pathog; 11(4): e1004834, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25909486

7.

Molecular mechanisms of hypoxic responses via unique roles of Ras1, Cdc24 and Ptp3 in a human fungal pathogen Cryptococcus neoformans.

Chang, Yun C; Khanal Lamichhane, Ami; Garraffo, H Martin; Walter, Peter J; Leerkes, Maarten; Kwon-Chung, Kyung J.

PLoS Genet; 10(4): e1004292, 2014 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-24762475

8.

Surface structure characterization of Aspergillus fumigatus conidia mutated in the melanin synthesis pathway and their human cellular immune response.

Bayry, Jagadeesh; Beaussart, Audrey; Dufrêne, Yves F; Sharma, Meenu; Bansal, Kushagra; Kniemeyer, Olaf; Aimanianda, Vishukumar; Brakhage, Axel A; Kaveri, Srini V; Kwon-Chung, Kyung J; Latgé, Jean-Paul; Beauvais, Anne.

Infect Immun; 82(8): 3141-53, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24818666

9.

Genetic relatedness versus biological compatibility between Aspergillus fumigatus and related species.

Sugui, Janyce A; Peterson, Stephen W; Figat, Abigail; Hansen, Bryan; Samson, Robert A; Mellado, Emilia; Cuenca-Estrella, Manuel; Kwon-Chung, Kyung J.

J Clin Microbiol; 52(10): 3707-21, 2014 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-25100816

10.

Aspergillosis, eosinophilic esophagitis, and allergic rhinitis in signal transducer and activator of transcription 3 haploinsufficiency.

Natarajan, Mukil; Hsu, Amy P; Weinreich, Michael A; Zhang, Yuan; Niemela, Julie E; Butman, John A; Pittaluga, Stefania; Sugui, Janyce; Collar, Amanda L; Lim, Jean K; Zangeneh, Tirdad; Carr, Tara; Oler, Andrew J; Similuk, Morgan; Rosen, Lindsey B; Desai, Jigar V; Freeman, Alexandra F; Holland, Steven M; Kwon-Chung, Kyung J; Milner, Joshua D; Lionakis, Michail S.

J Allergy Clin Immunol; 142(3): 993-997.e3, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-29803798

11.

Chloroquine modulates the fungal immune response in phagocytic cells from patients with chronic granulomatous disease.

Henriet, Stefanie S V; Jans, Jop; Simonetti, Elles; Kwon-Chung, Kyung J; Rijs, Antonius J M M; Hermans, Peter W M; Holland, Steve M; de Jonge, Marien I; Warris, Adilia.

J Infect Dis; 207(12): 1932-9, 2013 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-23482646

12.

Cryptococcus neoformans activates RhoGTPase proteins followed by protein kinase C, focal adhesion kinase, and ezrin to promote traversal across the blood-brain barrier.

Kim, Jong-Chul; Crary, Benjamin; Chang, Yun C; Kwon-Chung, Kyung J; Kim, Kee J.

J Biol Chem; 287(43): 36147-57, 2012 Oct 19.

Artículo en Inglés | MEDLINE | ID: mdl-22898813

13.

Hyaluronic acid receptor CD44 deficiency is associated with decreased Cryptococcus neoformans brain infection.

Jong, Ambrose; Wu, Chun-Hua; Gonzales-Gomez, Ignacio; Kwon-Chung, Kyung J; Chang, Yun C; Tseng, Hsiang-Kuang; Cho, Wen-Long; Huang, Sheng-He.

J Biol Chem; 287(19): 15298-306, 2012 May 04.

Artículo en Inglés | MEDLINE | ID: mdl-22418440

14.

Involvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans.

Lee, Hyeseung; Khanal Lamichhane, Ami; Garraffo, H Martin; Kwon-Chung, Kyung J; Chang, Yun C.

Mol Microbiol; 84(1): 130-46, 2012 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-22339665

15.

Azole heteroresistance in Cryptococcus neoformans: emergence of resistant clones with chromosomal disomy in the mouse brain during fluconazole treatment.

Sionov, Edward; Chang, Yun C; Kwon-Chung, Kyung J.

Antimicrob Agents Chemother; 57(10): 5127-30, 2013 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-23836187

16.

Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier.

Maruvada, Ravi; Zhu, Longkun; Pearce, Donna; Zheng, Yi; Perfect, John; Kwon-Chung, Kyung J; Kim, Kwang Sik.

Cell Microbiol; 14(10): 1544-53, 2012 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-22646320

17.

Role of actin-bundling protein Sac6 in growth of Cryptococcus neoformans at low oxygen concentration.

Chang, Yun C; Lamichhane, Ami Khanal; Kwon-Chung, Kyung J.

Eukaryot Cell; 11(7): 943-51, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22562467

18.

Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3).

Huang, Sheng-He; Long, Min; Wu, Chun-Hua; Kwon-Chung, Kyung J; Chang, Yun C; Chi, Feng; Lee, Susan; Jong, Ambrose.

J Biol Chem; 286(40): 34761-9, 2011 Oct 07.

Artículo en Inglés | MEDLINE | ID: mdl-21693704

19.

Taxonomy of fungi causing mucormycosis and entomophthoramycosis (zygomycosis) and nomenclature of the disease: molecular mycologic perspectives.

Kwon-Chung, Kyung J.

Clin Infect Dis; 54 Suppl 1: S8-S15, 2012 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-22247451

20.

Identification of a Cryptococcus neoformans cytochrome P450 lanosterol 14α-demethylase (Erg11) residue critical for differential susceptibility between fluconazole/voriconazole and itraconazole/posaconazole.

Sionov, Edward; Chang, Yun C; Garraffo, H Martin; Dolan, Michael A; Ghannoum, Mahmoud A; Kwon-Chung, Kyung J.

Antimicrob Agents Chemother; 56(3): 1162-9, 2012 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-22155829

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