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1.

Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.

Su, Zhaoming; Wu, Chao; Shi, Liuqing; Luthra, Priya; Pintilie, Grigore D; Johnson, Britney; Porter, Justin R; Ge, Peng; Chen, Muyuan; Liu, Gai; Frederick, Thomas E; Binning, Jennifer M; Bowman, Gregory R; Zhou, Z Hong; Basler, Christopher F; Gross, Michael L; Leung, Daisy W; Chiu, Wah; Amarasinghe, Gaya K.

Cell; 172(5): 966-978.e12, 2018 02 22.

Artículo en Inglés | MEDLINE | ID: mdl-29474922

2.

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.

Batra, Jyoti; Hultquist, Judd F; Liu, Dandan; Shtanko, Olena; Von Dollen, John; Satkamp, Laura; Jang, Gwendolyn M; Luthra, Priya; Schwarz, Toni M; Small, Gabriel I; Arnett, Eusondia; Anantpadma, Manu; Reyes, Ann; Leung, Daisy W; Kaake, Robyn; Haas, Paige; Schmidt, Carson B; Schlesinger, Larry S; LaCount, Douglas J; Davey, Robert A; Amarasinghe, Gaya K; Basler, Christopher F; Krogan, Nevan J.

Cell; 175(7): 1917-1930.e13, 2018 12 13.

Artículo en Inglés | MEDLINE | ID: mdl-30550789

3.

Impact of Menglà Virus Proteins on Human and Bat Innate Immune Pathways.

Williams, Caroline G; Gibbons, Joyce Sweeney; Keiffer, Timothy R; Luthra, Priya; Edwards, Megan R; Basler, Christopher F.

J Virol; 94(13)2020 06 16.

Artículo en Inglés | MEDLINE | ID: mdl-32295912

4.

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication.

Bharaj, Preeti; Atkins, Colm; Luthra, Priya; Giraldo, Maria Isabel; Dawes, Brian E; Miorin, Lisa; Johnson, Jeffrey R; Krogan, Nevan J; Basler, Christopher F; Freiberg, Alexander N; Rajsbaum, Ricardo.

J Virol; 91(18)2017 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-28679761

5.

Ebola virus VP35 interaction with dynein LC8 regulates viral RNA synthesis.

Luthra, Priya; Jordan, David S; Leung, Daisy W; Amarasinghe, Gaya K; Basler, Christopher F.

J Virol; 89(9): 5148-53, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25741013

6.

Activation of IFN-β expression by a viral mRNA through RNase L and MDA5.

Luthra, Priya; Sun, Dengyun; Silverman, Robert H; He, Biao.

Proc Natl Acad Sci U S A; 108(5): 2118-23, 2011 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-21245317

7.

Development of RNA aptamers targeting Ebola virus VP35.

Binning, Jennifer M; Wang, Tianjiao; Luthra, Priya; Shabman, Reed S; Borek, Dominika M; Liu, Gai; Xu, Wei; Leung, Daisy W; Basler, Christopher F; Amarasinghe, Gaya K.

Biochemistry; 52(47): 8406-19, 2013 Nov 26.

Artículo en Inglés | MEDLINE | ID: mdl-24067086

8.

The V protein of mumps virus plays a critical role in pathogenesis.

Xu, Pei; Luthra, Priya; Li, Zhuo; Fuentes, Sandra; D'Andrea, James Alexander; Wu, Jianguo; Rubin, Steven; Rota, Paul A; He, Biao.

J Virol; 86(3): 1768-76, 2012 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-22090137

9.

Identification of a phosphorylation site within the P protein important for mRNA transcription and growth of parainfluenza virus 5.

Sun, Dengyun; Luthra, Priya; Xu, Pei; Yoon, Haeyoung; He, Biao.

J Virol; 85(16): 8376-85, 2011 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-21680523

10.

PLK1 down-regulates parainfluenza virus 5 gene expression.

Sun, Dengyun; Luthra, Priya; Li, Zhuo; He, Biao.

PLoS Pathog; 5(7): e1000525, 2009 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-19629176

11.

Cardiac inflammation in COVID-19: Lessons from heart failure.

Unudurthi, Sathya D; Luthra, Priya; Bose, Rajendran J C; McCarthy, Jason R; Kontaridis, Maria Irene.

Life Sci; 260: 118482, 2020 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-32971105

12.

High-Throughput Screening Assay to Identify Small Molecule Inhibitors of Marburg Virus VP40 Protein.

Luthra, Priya; Anantpadma, Manu; De, Sampriti; Sourimant, Julien; Davey, Robert A; Plemper, Richard K; Basler, Christopher F.

ACS Infect Dis; 6(10): 2783-2799, 2020 10 09.

Artículo en Inglés | MEDLINE | ID: mdl-32870648

13.

AKT1-dependent activation of NF-kappaB by the L protein of parainfluenza virus 5.

Luthra, Priya; Sun, Dengyun; Wolfgang, Matthew; He, Biao.

J Virol; 82(21): 10887-95, 2008 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-18715928

14.

Inhibition of Marburg Virus RNA Synthesis by a Synthetic Anti-VP35 Antibody.

Amatya, Parmeshwar; Wagner, Nicole; Chen, Gang; Luthra, Priya; Shi, Liuqing; Borek, Dominika; Pavlenco, Alevtina; Rohrs, Henry; Basler, Christopher F; Sidhu, Sachdev S; Gross, Michael L; Leung, Daisy W.

ACS Infect Dis; 5(8): 1385-1396, 2019 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-31120240

15.

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge.

Woolsey, Courtney; Menicucci, Andrea R; Cross, Robert W; Luthra, Priya; Agans, Krystle N; Borisevich, Viktoriya; Geisbert, Joan B; Mire, Chad E; Fenton, Karla A; Jankeel, Allen; Anand, Sneha; Ebihara, Hideki; Geisbert, Thomas W; Messaoudi, Ilhem; Basler, Christopher F.

Cell Rep; 28(12): 3032-3046.e6, 2019 09 17.

Artículo en Inglés | MEDLINE | ID: mdl-31533029

16.

Severe influenza pneumonitis in children with inherited TLR3 deficiency.

Lim, Hye Kyung; Huang, Sarah X L; Chen, Jie; Kerner, Gaspard; Gilliaux, Olivier; Bastard, Paul; Dobbs, Kerry; Hernandez, Nicholas; Goudin, Nicolas; Hasek, Mary L; García Reino, Eduardo Javier; Lafaille, Fabien G; Lorenzo, Lazaro; Luthra, Priya; Kochetkov, Tatiana; Bigio, Benedetta; Boucherit, Soraya; Rozenberg, Flore; Vedrinne, Catherine; Keller, Michael D; Itan, Yuval; García-Sastre, Adolfo; Celard, Marie; Orange, Jordan S; Ciancanelli, Michael J; Meyts, Isabelle; Zhang, Qian; Abel, Laurent; Notarangelo, Luigi D; Snoeck, Hans-Willem; Casanova, Jean-Laurent; Zhang, Shen-Ying.

J Exp Med; 216(9): 2038-2056, 2019 09 02.

Artículo en Inglés | MEDLINE | ID: mdl-31217193

17.

A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication.

Luthra, Priya; Liang, Jue; Pietzsch, Colette A; Khadka, Sudip; Edwards, Megan R; Wei, Shuguang; De, Sampriti; Posner, Bruce; Bukreyev, Alexander; Ready, Joseph M; Basler, Christopher F.

Antiviral Res; 150: 193-201, 2018 02.

Artículo en Inglés | MEDLINE | ID: mdl-29294299

18.

The Antiviral Drug Arbidol Inhibits Zika Virus.

Fink, Susan L; Vojtech, Lucia; Wagoner, Jessica; Slivinski, Natalie S J; Jackson, Konner J; Wang, Ruofan; Khadka, Sudip; Luthra, Priya; Basler, Christopher F; Polyak, Stephen J.

Sci Rep; 8(1): 8989, 2018 06 12.

Artículo en Inglés | MEDLINE | ID: mdl-29895962

19.

Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.

Luthra, Priya; Naidoo, Jacinth; Pietzsch, Colette A; De, Sampriti; Khadka, Sudip; Anantpadma, Manu; Williams, Caroline G; Edwards, Megan R; Davey, Robert A; Bukreyev, Alexander; Ready, Joseph M; Basler, Christopher F.

Antiviral Res; 158: 288-302, 2018 10.

Artículo en Inglés | MEDLINE | ID: mdl-30144461

20.

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

Edwards, Megan R; Liu, Hejun; Shabman, Reed S; Ginell, Garrett M; Luthra, Priya; Ramanan, Parmeshwaran; Keefe, Lisa J; Köllner, Bernd; Amarasinghe, Gaya K; Taylor, Derek J; Leung, Daisy W; Basler, Christopher F.

Cell Rep; 24(4): 861-872.e6, 2018 07 24.

Artículo en Inglés | MEDLINE | ID: mdl-30044983

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