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1.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

Hou, Yixuan J; Okuda, Kenichi; Edwards, Caitlin E; Martinez, David R; Asakura, Takanori; Dinnon, Kenneth H; Kato, Takafumi; Lee, Rhianna E; Yount, Boyd L; Mascenik, Teresa M; Chen, Gang; Olivier, Kenneth N; Ghio, Andrew; Tse, Longping V; Leist, Sarah R; Gralinski, Lisa E; Schäfer, Alexandra; Dang, Hong; Gilmore, Rodney; Nakano, Satoko; Sun, Ling; Fulcher, M Leslie; Livraghi-Butrico, Alessandra; Nicely, Nathan I; Cameron, Mark; Cameron, Cheryl; Kelvin, David J; de Silva, Aravinda; Margolis, David M; Markmann, Alena; Bartelt, Luther; Zumwalt, Ross; Martinez, Fernando J; Salvatore, Steven P; Borczuk, Alain; Tata, Purushothama R; Sontake, Vishwaraj; Kimple, Adam; Jaspers, Ilona; O'Neal, Wanda K; Randell, Scott H; Boucher, Richard C; Baric, Ralph S.

Cell; 2020 May 27.

Artículo en Inglés | MEDLINE | ID: covidwho-381993

2.

Curing HIV: Seeking to Target and Clear Persistent Infection.

Margolis, David M; Archin, Nancie M; Cohen, Myron S; Eron, Joseph J; Ferrari, Guido; Garcia, J Victor; Gay, Cynthia L; Goonetilleke, Nilu; Joseph, Sarah B; Swanstrom, Ronald; Turner, Anne-Marie W; Wahl, Angela.

Cell; 181(1): 189-206, 2020 04 02.

Artículo en Inglés | MEDLINE | ID: mdl-32220311

3.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

Hou, Yixuan J; Okuda, Kenichi; Edwards, Caitlin E; Martinez, David R; Asakura, Takanori; Dinnon, Kenneth H; Kato, Takafumi; Lee, Rhianna E; Yount, Boyd L; Mascenik, Teresa M; Chen, Gang; Olivier, Kenneth N; Ghio, Andrew; Tse, Longping V; Leist, Sarah R; Gralinski, Lisa E; Schäfer, Alexandra; Dang, Hong; Gilmore, Rodney; Nakano, Satoko; Sun, Ling; Fulcher, M Leslie; Livraghi-Butrico, Alessandra; Nicely, Nathan I; Cameron, Mark; Cameron, Cheryl; Kelvin, David J; de Silva, Aravinda; Margolis, David M; Markmann, Alena; Bartelt, Luther; Zumwalt, Ross; Martinez, Fernando J; Salvatore, Steven P; Borczuk, Alain; Tata, Purushothama R; Sontake, Vishwaraj; Kimple, Adam; Jaspers, Ilona; O'Neal, Wanda K; Randell, Scott H; Boucher, Richard C; Baric, Ralph S.

Cell; 182(2): 429-446.e14, 2020 07 23.

Artículo en Inglés | MEDLINE | ID: mdl-32526206

4.

Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8⁺ cells.

McBrien, Julia Bergild; Mavigner, Maud; Franchitti, Lavinia; Smith, S Abigail; White, Erick; Tharp, Gregory K; Walum, Hasse; Busman-Sahay, Kathleen; Aguilera-Sandoval, Christian R; Thayer, William O; Spagnuolo, Rae Ann; Kovarova, Martina; Wahl, Angela; Cervasi, Barbara; Margolis, David M; Vanderford, Thomas H; Carnathan, Diane G; Paiardini, Mirko; Lifson, Jeffrey D; Lee, John H; Safrit, Jeffrey T; Bosinger, Steven E; Estes, Jacob D; Derdeyn, Cynthia A; Garcia, J Victor; Kulpa, Deanna A; Chahroudi, Ann; Silvestri, Guido.

Nature; 578(7796): E21, 2020 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-32015546

5.

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8⁺ cells.

McBrien, Julia Bergild; Mavigner, Maud; Franchitti, Lavinia; Smith, S Abigail; White, Erick; Tharp, Gregory K; Walum, Hasse; Busman-Sahay, Kathleen; Aguilera-Sandoval, Christian R; Thayer, William O; Spagnuolo, Rae Ann; Kovarova, Martina; Wahl, Angela; Cervasi, Barbara; Margolis, David M; Vanderford, Thomas H; Carnathan, Diane G; Paiardini, Mirko; Lifson, Jeffrey D; Lee, John H; Safrit, Jeffrey T; Bosinger, Steven E; Estes, Jacob D; Derdeyn, Cynthia A; Garcia, J Victor; Kulpa, Deanna A; Chahroudi, Ann; Silvestri, Guido.

Nature; 578(7793): 154-159, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31969705

6.

Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo.

Nixon, Christopher C; Mavigner, Maud; Sampey, Gavin C; Brooks, Alyssa D; Spagnuolo, Rae Ann; Irlbeck, David M; Mattingly, Cameron; Ho, Phong T; Schoof, Nils; Cammon, Corinne G; Tharp, Greg K; Kanke, Matthew; Wang, Zhang; Cleary, Rachel A; Upadhyay, Amit A; De, Chandrav; Wills, Saintedym R; Falcinelli, Shane D; Galardi, Cristin; Walum, Hasse; Schramm, Nathaniel J; Deutsch, Jennifer; Lifson, Jeffrey D; Fennessey, Christine M; Keele, Brandon F; Jean, Sherrie; Maguire, Sean; Liao, Baolin; Browne, Edward P; Ferris, Robert G; Brehm, Jessica H; Favre, David; Vanderford, Thomas H; Bosinger, Steven E; Jones, Corbin D; Routy, Jean-Pierre; Archin, Nancie M; Margolis, David M; Wahl, Angela; Dunham, Richard M; Silvestri, Guido; Chahroudi, Ann; Garcia, J Victor.

Nature; 578(7793): 160-165, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31969707

7.

HIV antibodies for treatment of HIV infection.

Margolis, David M; Koup, Richard A; Ferrari, Guido.

Immunol Rev; 275(1): 313-323, 2017 01.

Artículo en Inglés | MEDLINE | ID: mdl-28133794

8.

Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat.

Maxwell, Jill W; Falcinelli, Shane D; Nefedov, Alexey; Dorfmeier, Corin; Wu, Guoxin; Dewey, Morgan; Webber, Andrea L; Archin, Nancie M; Margolis, David M; Hazuda, Daria J; Barnard, Richard J O; Howell, Bonnie J.

J Virol; 94(13)2020 06 16.

Artículo en Inglés | MEDLINE | ID: mdl-32295913

9.

SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.

Dashti, Amir; Waller, Chevaughn; Mavigner, Maud; Schoof, Nils; Bar, Katharine J; Shaw, George M; Vanderford, Thomas H; Liang, Shan; Lifson, Jeffrey D; Dunham, Richard M; Ferrari, Guido; Tuyishime, Marina; Lam, Chia-Ying K; Nordstrom, Jeffrey L; Margolis, David M; Silvestri, Guido; Chahroudi, Ann.

J Virol; 94(21)2020 10 14.

Artículo en Inglés | MEDLINE | ID: mdl-32817214

10.

Sequence evaluation and comparative analysis of novel assays for intact proviral HIV-1 DNA.

Gaebler, Christian; Falcinelli, Shane D; Stoffel, Elina; Read, Jenna; Murtagh, Ross; Oliveira, Thiago Y; Ramos, Victor; Lorenzi, Julio C C; Kirchherr, Jennifer; James, Katherine S; Allard, Brigitte; Baker, Caroline; Kuruc, JoAnn D; Caskey, Marina; Archin, Nancie M; Siliciano, Robert F; Margolis, David M; Nussenzweig, Michel C.

J Virol; 2020 Dec 23.

Artículo en Inglés | MEDLINE | ID: mdl-33361426

11.

How Unavoidable Are Analytical Treatment Interruptions in HIV Cure-Related Studies?

Margolis, David M; Deeks, Steven G.

J Infect Dis; 220(220 Suppl 1): S24-S26, 2019 07 02.

Artículo en Inglés | MEDLINE | ID: mdl-31264691

12.

Longitudinal dynamics of intact HIV proviral DNA and outgrowth virus frequencies in a cohort of ART-treated individuals.

Falcinelli, Shane D; Kilpatrick, Kayla W; Read, Jenna; Murtagh, Ross; Allard, Brigitte; Ghofrani, Simon; Kirchherr, Jennifer; James, Katherine S; Stuelke, Erin; Baker, Caroline; Kuruc, JoAnn D; Eron, Joseph J; Hudgens, Michael G; Gay, Cynthia L; Margolis, David M; Archin, Nancie M.

J Infect Dis; 2020 Nov 20.

Artículo en Inglés | MEDLINE | ID: mdl-33216132

13.

Impact of Biological Sex on Immune Activation and Frequency of the Latent HIV Reservoir During Suppressive Antiretroviral Therapy.

Falcinelli, Shane D; Shook-Sa, Bonnie E; Dewey, Morgan G; Sridhar, Sumati; Read, Jenna; Kirchherr, Jennifer; James, Katherine S; Allard, Brigitte; Ghofrani, Simon; Stuelke, Erin; Baker, Caroline; Roan, Nadia R; Eron, Joseph J; Kuruc, JoAnn D; Ramirez, Catalina; Gay, Cynthia; Mollan, Katie R; Margolis, David M; Adimora, Adaora A; Archin, Nancie M.

J Infect Dis; 222(11): 1843-1852, 2020 Nov 09.

Artículo en Inglés | MEDLINE | ID: mdl-32496542

14.

Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo.

Garrido, Carolina; Abad-Fernandez, Maria; Tuyishime, Marina; Pollara, Justin J; Ferrari, Guido; Soriano-Sarabia, Natalia; Margolis, David M.

J Virol; 92(12)2018 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-29593039

15.

HIV-Specific T Cells Generated from Naive T Cells Suppress HIV In Vitro and Recognize Wide Epitope Breadths.

Patel, Shabnum; Chorvinsky, Elizabeth; Albihani, Shuroug; Cruz, Conrad Russell; Jones, R Brad; Shpall, Elizabeth J; Margolis, David M; Ambinder, Richard F; Bollard, Catherine M.

Mol Ther; 26(6): 1435-1446, 2018 06 06.

Artículo en Inglés | MEDLINE | ID: mdl-29724686

16.

HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals.

Sung, Julia A; Patel, Shabnum; Clohosey, Matthew L; Roesch, Lauren; Tripic, Tamara; Kuruc, JoAnn D; Archin, Nancie; Hanley, Patrick J; Cruz, C Russell; Goonetilleke, Nilu; Eron, Joseph J; Rooney, Clio M; Gay, Cynthia L; Bollard, Catherine M; Margolis, David M.

Mol Ther; 26(10): 2496-2506, 2018 10 03.

Artículo en Inglés | MEDLINE | ID: mdl-30249388

17.

Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.

White, Cory H; Moesker, Bastiaan; Beliakova-Bethell, Nadejda; Martins, Laura J; Spina, Celsa A; Margolis, David M; Richman, Douglas D; Planelles, Vicente; Bosque, Alberto; Woelk, Christopher H.

PLoS Pathog; 12(11): e1006026, 2016 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-27898737

18.

Correction to: HIV Persistence on Antiretroviral Therapy and Barriers to a Cure.

Sung, Julia Marsh; Margolis, David M.

Adv Exp Med Biol; 1075: E1, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30196367

19.

HIV Persistence on Antiretroviral Therapy and Barriers to a Cure.

Sung, Julia Marsh; Margolis, David M.

Adv Exp Med Biol; 1075: 165-185, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30030793

20.

Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents.

Margolis, David M; Archin, Nancie M.

J Infect Dis; 215(suppl_3): S111-S118, 2017 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-28520964

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SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

Curing HIV: Seeking to Target and Clear Persistent Infection.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8⁺ cells.

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8⁺ cells.

Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo.

HIV antibodies for treatment of HIV infection.

Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat.

SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.

Sequence evaluation and comparative analysis of novel assays for intact proviral HIV-1 DNA.

How Unavoidable Are Analytical Treatment Interruptions in HIV Cure-Related Studies?

Longitudinal dynamics of intact HIV proviral DNA and outgrowth virus frequencies in a cohort of ART-treated individuals.

Impact of Biological Sex on Immune Activation and Frequency of the Latent HIV Reservoir During Suppressive Antiretroviral Therapy.

Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo.

HIV-Specific T Cells Generated from Naive T Cells Suppress HIV In Vitro and Recognize Wide Epitope Breadths.

HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals.

Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.

Correction to: HIV Persistence on Antiretroviral Therapy and Barriers to a Cure.

HIV Persistence on Antiretroviral Therapy and Barriers to a Cure.

Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents.