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1.

Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation.

Gou, Lan-Tao; Lim, Do-Hwan; Ma, Wubin; Aubol, Brandon E; Hao, Yajing; Wang, Xin; Zhao, Jun; Liang, Zhengyu; Shao, Changwei; Zhang, Xuan; Meng, Fan; Li, Hairi; Zhang, Xiaorong; Xu, Ruiming; Li, Dangsheng; Rosenfeld, Michael G; Mellon, Pamela L; Adams, Joseph A; Liu, Mo-Fang; Fu, Xiang-Dong.

Cell; 180(6): 1212-1227.e14, 2020 03 19.

Artículo en Inglés | MEDLINE | ID: mdl-32169215

2.

Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin; Gonen, Ayelet; Prohaska, Thomas A; Sun, Xiaoli; Diehl, Cody; Määttä, Antti; Gaddis, Dalia E; Bowden, Karen; Pattison, Jennifer; MacDonald, Jeffrey G; Ylä-Herttuala, Seppo; Mellon, Pamela L; Hedrick, Catherine C; Ley, Klaus; Miller, Yury I; Glass, Christopher K; Peterson, Kirk L; Binder, Christoph J; Tsimikas, Sotirios; Witztum, Joseph L.

Nature; 561(7724): E43, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30013121

3.

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que, Xuchu; Hung, Ming-Yow; Yeang, Calvin; Gonen, Ayelet; Prohaska, Thomas A; Sun, Xiaoli; Diehl, Cody; Määttä, Antti; Gaddis, Dalia E; Bowden, Karen; Pattison, Jennifer; MacDonald, Jeffrey G; Ylä-Herttuala, Seppo; Mellon, Pamela L; Hedrick, Catherine C; Ley, Klaus; Miller, Yury I; Glass, Christopher K; Peterson, Kirk L; Binder, Christoph J; Tsimikas, Sotirios; Witztum, Joseph L.

Nature; 558(7709): 301-306, 2018 06.

Artículo en Inglés | MEDLINE | ID: mdl-29875409

4.

P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma.

Skowronska-Krawczyk, Dorota; Zhao, Ling; Zhu, Jie; Weinreb, Robert N; Cao, Guiqun; Luo, Jing; Flagg, Ken; Patel, Sherrina; Wen, Cindy; Krupa, Martin; Luo, Hongrong; Ouyang, Hong; Lin, Danni; Wang, Wenqiu; Li, Gen; Xu, Yanxin; Li, Oulan; Chung, Christopher; Yeh, Emily; Jafari, Maryam; Ai, Michael; Zhong, Zheng; Shi, William; Zheng, Lianghong; Krawczyk, Michal; Chen, Daniel; Shi, Catherine; Zin, Carolyn; Zhu, Jin; Mellon, Pamela L; Gao, Weiwei; Abagyan, Ruben; Zhang, Liangfang; Sun, Xiaodong; Zhong, Sheng; Zhuo, Yehong; Rosenfeld, Michael G; Liu, Yizhi; Zhang, Kang.

Mol Cell; 59(6): 931-40, 2015 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-26365380

5.

Haploinsufficiency of Homeodomain Proteins Six3, Vax1, and Otx2 Causes Subfertility in Mice via Distinct Mechanisms.

Hoffmann, Hanne M; Pandolfi, Erica C; Larder, Rachel; Mellon, Pamela L.

Neuroendocrinology; 109(3): 200-207, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-30261489

6.

Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flox Mice.

Hoffmann, Hanne M; Larder, Rachel; Lee, Jessica S; Hu, Rachael J; Trang, Crystal; Devries, Brooke M; Clark, Daniel D; Mellon, Pamela L.

Neuroendocrinology; 108(4): 328-342, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-30739114

7.

Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility.

Hoffmann, Hanne M; Trang, Crystal; Gong, Ping; Kimura, Ikuo; Pandolfi, Erica C; Mellon, Pamela L.

J Neurosci; 36(12): 3506-18, 2016 Mar 23.

Artículo en Inglés | MEDLINE | ID: mdl-27013679

8.

Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines.

Xie, Huimin; Hoffmann, Hanne M; Iyer, Anita K; Brayman, Melissa J; Ngo, Cindy; Sunshine, Mary Jean; Mellon, Pamela L.

Reprod Biol Endocrinol; 15(1): 86, 2017 Oct 24.

Artículo en Inglés | MEDLINE | ID: mdl-29065928

9.

A Novel Letrozole Model Recapitulates Both the Reproductive and Metabolic Phenotypes of Polycystic Ovary Syndrome in Female Mice.

Kauffman, Alexander S; Thackray, Varykina G; Ryan, Genevieve E; Tolson, Kristen P; Glidewell-Kenney, Christine A; Semaan, Sheila J; Poling, Matthew C; Iwata, Nahoko; Breen, Kellie M; Duleba, Antoni J; Stener-Victorin, Elisabet; Shimasaki, Shunichi; Webster, Nicholas J; Mellon, Pamela L.

Biol Reprod; 93(3): 69, 2015 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-26203175

10.

Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6.

Larder, Rachel; Clark, Daniel D; Miller, Nichol L G; Mellon, Pamela L.

J Neurosci; 31(2): 426-38, 2011 Jan 12.

Artículo en Inglés | MEDLINE | ID: mdl-21228153

11.

Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.

Miller, Nichol L G; Wevrick, Rachel; Mellon, Pamela L.

Hum Mol Genet; 18(2): 248-60, 2009 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-18930956

12.

PPARG regulates gonadotropin-releasing hormone signaling in LbetaT2 cells in vitro and pituitary gonadotroph function in vivo in mice.

Sharma, Shweta; Sharma, Prem M; Mistry, Devendra S; Chang, R Jeffery; Olefsky, Jerrold M; Mellon, Pamela L; Webster, Nicholas J G.

Biol Reprod; 84(3): 466-75, 2011 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-21076077

13.

Growth Hormone Pulses and Liver Gene Expression Are Differentially Regulated by the Circadian Clock Gene Bmal1.

Schoeller, Erica L; Tonsfeldt, Karen J; Sinkovich, McKenna; Shi, Rujing; Mellon, Pamela L.

Endocrinology; 162(4)2021 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-33539533

14.

Otx2 induction of the gonadotropin-releasing hormone promoter is modulated by direct interactions with Grg co-repressors.

Larder, Rachel; Mellon, Pamela L.

J Biol Chem; 284(25): 16966-78, 2009 Jun 19.

Artículo en Inglés | MEDLINE | ID: mdl-19401468

15.

FSHB Transcription is Regulated by a Novel 5' Distal Enhancer with a Fertility-Associated Single Nucleotide Polymorphism.

Bohaczuk, Stephanie C; Thackray, Varykina G; Shen, Jia; Skowronska-Krawczyk, Dorota; Mellon, Pamela L.

Endocrinology; 2020 Oct 03.

Artículo en Inglés | MEDLINE | ID: mdl-33009549

16.

Stem cell regionalization during olfactory bulb neurogenesis depends on regulatory interactions between Vax1 and Pax6.

Coré, Nathalie; Erni, Andrea; Hoffmann, Hanne M; Mellon, Pamela L; Saurin, Andrew J; Beclin, Christophe; Cremer, Harold.

Elife; 92020 08 07.

Artículo en Inglés | MEDLINE | ID: mdl-32762844

17.

GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes.

Nicholas, Dequina A; Knight, Vashti S; Tonsfeldt, Karen J; Terasaka, Tomohiro; Molinar-Inglis, Olivia; Stephens, Shannon B Z; Trejo, JoAnn; Kauffman, Alexander S; Mellon, Pamela L; Lawson, Mark A.

Sci Rep; 10(1): 13063, 2020 08 03.

Artículo en Inglés | MEDLINE | ID: mdl-32747664

18.

The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function.

Pandolfi, Erica C; Breuer, Joseph A; Nguyen Huu, Viet Anh; Talluri, Tulasi; Nguyen, Duong; Lee, Jessica Sora; Hu, Rachael; Bharti, Kapil; Skowronska-Krawczyk, Dorota; Gorman, Michael R; Mellon, Pamela L; Hoffmann, Hanne M.

Mol Neurobiol; 57(2): 1217-1232, 2020 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-31705443

19.

Leptin increases L-type Ca2+ channel expression and GnRH-stimulated LH release in LbetaT2 gonadotropes.

Avelino-Cruz, José E; Flores, Amira; Cebada, Jorge; Mellon, Pamela L; Felix, Ricardo; Monjaraz, Eduardo.

Mol Cell Endocrinol; 298(1-2): 57-65, 2009 Jan 27.

Artículo en Inglés | MEDLINE | ID: mdl-18834922

20.

Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LbetaT2 gonadotropes.

Lu, Min; Tang, Qingbo; Olefsky, Jerrold M; Mellon, Pamela L; Webster, Nicholas J G.

Mol Endocrinol; 22(3): 760-71, 2008 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-18006641

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