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1.

Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection.

Shi, Zhenda; Zou, Jun; Zhang, Zhan; Zhao, Xu; Noriega, Juan; Zhang, Benyue; Zhao, Chunyu; Ingle, Harshad; Bittinger, Kyle; Mattei, Lisa M; Pruijssers, Andrea J; Plemper, Richard K; Nice, Timothy J; Baldridge, Megan T; Dermody, Terence S; Chassaing, Benoit; Gewirtz, Andrew T.

Cell; 179(3): 644-658.e13, 2019 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-31607511

2.

You Can Breathe Easy: IFNλ Handles Flu without Triggering a Damaging Inflammatory Response.

Robinson, Bridget A; Nice, Timothy J.

Immunity; 46(5): 768-770, 2017 05 16.

Artículo en Inglés | MEDLINE | ID: mdl-28514682

3.

Differentiation and Protective Capacity of Virus-Specific CD8⁺ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche.

Tomov, Vesselin T; Palko, Olesya; Lau, Chi Wai; Pattekar, Ajinkya; Sun, Yuhang; Tacheva, Ralitza; Bengsch, Bertram; Manne, Sasikanth; Cosma, Gabriela L; Eisenlohr, Laurence C; Nice, Timothy J; Virgin, Herbert W; Wherry, E John.

Immunity; 47(4): 723-738.e5, 2017 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-29031786

4.

Interferon-λ: Immune Functions at Barrier Surfaces and Beyond.

Lazear, Helen M; Nice, Timothy J; Diamond, Michael S.

Immunity; 43(1): 15-28, 2015 Jul 21.

Artículo en Inglés | MEDLINE | ID: mdl-26200010

5.

Selective Interferon Responses of Intestinal Epithelial Cells Minimize Tumor Necrosis Factor Alpha Cytotoxicity.

Van Winkle, Jacob A; Constant, David A; Li, Lena; Nice, Timothy J.

J Virol; 94(21)2020 Oct 14.

Artículo en Inglés | MEDLINE | ID: mdl-32847859

6.

CD300lf conditional knockout mouse reveals strain-specific cellular tropism for murine norovirus.

Graziano, Vincent R; Alfajaro, Mia Madel; Schmitz, Cameron O; Filler, Renata B; Strine, Madison S; Wei, Jin; Hsieh, Leon L; Baldridge, Megan T; Nice, Timothy J; Lee, Sanghyun; Orchard, Robert C; Wilen, Craig B.

J Virol; 2020 Nov 11.

Artículo en Inglés | MEDLINE | ID: mdl-33177207

7.

Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells.

Robinson, Bridget A; Van Winkle, Jacob A; McCune, Broc T; Peters, A Mack; Nice, Timothy J.

PLoS Pathog; 15(7): e1007940, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31329638

8.

HOIL1 Is Essential for the Induction of Type I and III Interferons by MDA5 and Regulates Persistent Murine Norovirus Infection.

MacDuff, Donna A; Baldridge, Megan T; Qaqish, Arwa M; Nice, Timothy J; Darbandi, Azad D; Hartley, Victoria L; Peterson, Stefan T; Miner, Jonathan J; Iwai, Kazuhiro; Virgin, Herbert W.

J Virol; 92(23)2018 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-30209176

9.

Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.

Nice, Timothy J; Osborne, Lisa C; Tomov, Vesselin T; Artis, David; Wherry, E John; Virgin, Herbert W.

PLoS Pathog; 13(2): e1006223, 2017 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-28212439

10.

Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus.

Baldridge, Megan T; Lee, Sanghyun; Brown, Judy J; McAllister, Nicole; Urbanek, Kelly; Dermody, Terence S; Nice, Timothy J; Virgin, Herbert W.

J Virol; 91(7)2017 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-28077655

11.

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.

Nice, Timothy J; Osborne, Lisa C; Tomov, Vesselin T; Artis, David; Wherry, E John; Virgin, Herbert W.

PLoS Pathog; 12(6): e1005684, 2016 06.

Artículo en Inglés | MEDLINE | ID: mdl-27327515

12.

Murine norovirus protein NS1/2 aspartate to glutamate mutation, sufficient for persistence, reorients side chain of surface exposed tryptophan within a novel structured domain.

Borin, Brendan N; Tang, Wei; Nice, Timothy J; McCune, Broc T; Virgin, Herbert W; Krezel, Andrzej M.

Proteins; 82(7): 1200-9, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24273131

13.

A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence.

Nice, Timothy J; Strong, David W; McCune, Broc T; Pohl, Calvin S; Virgin, Herbert W.

J Virol; 87(1): 327-34, 2013 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-23077309

14.

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.

Nice, Timothy J; Deng, Weiwen; Coscoy, Laurent; Raulet, David H.

J Immunol; 185(9): 5369-76, 2010 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-20870941

15.

IFN-I and IL-22 mediate protective effects of intestinal viral infection.

Neil, Jessica A; Matsuzawa-Ishimoto, Yu; Kernbauer-Hölzl, Elisabeth; Schuster, Samantha L; Sota, Stela; Venzon, Mericien; Dallari, Simone; Galvao Neto, Antonio; Hine, Ashley; Hudesman, David; Loke, P'ng; Nice, Timothy J; Cadwell, Ken.

Nat Microbiol; 4(10): 1737-1749, 2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-31182797

16.

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis.

Lee, Sanghyun; Liu, Hejun; Wilen, Craig B; Sychev, Zoi E; Desai, Chandni; Hykes, Barry L; Orchard, Robert C; McCune, Broc T; Kim, Ki-Wook; Nice, Timothy J; Handley, Scott A; Baldridge, Megan T; Amarasinghe, Gaya K; Virgin, Herbert W.

Cell Host Microbe; 25(6): 845-857.e5, 2019 06 12.

Artículo en Inglés | MEDLINE | ID: mdl-31130511

17.

The Role of Interferon in Persistent Viral Infection: Insights from Murine Norovirus.

Nice, Timothy J; Robinson, Bridget A; Van Winkle, Jacob A.

Trends Microbiol; 26(6): 510-524, 2018 06.

Artículo en Inglés | MEDLINE | ID: mdl-29157967

18.

Persistence of Systemic Murine Norovirus Is Maintained by Inflammatory Recruitment of Susceptible Myeloid Cells.

Van Winkle, Jacob A; Robinson, Bridget A; Peters, A Mack; Li, Lena; Nouboussi, Ruth V; Mack, Matthias; Nice, Timothy J.

Cell Host Microbe; 24(5): 665-676.e4, 2018 11 14.

Artículo en Inglés | MEDLINE | ID: mdl-30392829

19.

Norovirus Cell Tropism Is Determined by Combinatorial Action of a Viral Non-structural Protein and Host Cytokine.

Lee, Sanghyun; Wilen, Craig B; Orvedahl, Anthony; McCune, Broc T; Kim, Ki-Wook; Orchard, Robert C; Peterson, Stefan T; Nice, Timothy J; Baldridge, Megan T; Virgin, Herbert W.

Cell Host Microbe; 22(4): 449-459.e4, 2017 Oct 11.

Artículo en Inglés | MEDLINE | ID: mdl-28966054

20.

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2.

McCune, Broc T; Tang, Wei; Lu, Jia; Eaglesham, James B; Thorne, Lucy; Mayer, Anne E; Condiff, Emily; Nice, Timothy J; Goodfellow, Ian; Krezel, Andrzej M; Virgin, Herbert W.

mBio; 8(4)2017 07 11.

Artículo en Inglés | MEDLINE | ID: mdl-28698274

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