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1.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

Hou, Yixuan J; Okuda, Kenichi; Edwards, Caitlin E; Martinez, David R; Asakura, Takanori; Dinnon, Kenneth H; Kato, Takafumi; Lee, Rhianna E; Yount, Boyd L; Mascenik, Teresa M; Chen, Gang; Olivier, Kenneth N; Ghio, Andrew; Tse, Longping V; Leist, Sarah R; Gralinski, Lisa E; Schäfer, Alexandra; Dang, Hong; Gilmore, Rodney; Nakano, Satoko; Sun, Ling; Fulcher, M Leslie; Livraghi-Butrico, Alessandra; Nicely, Nathan I; Cameron, Mark; Cameron, Cheryl; Kelvin, David J; de Silva, Aravinda; Margolis, David M; Markmann, Alena; Bartelt, Luther; Zumwalt, Ross; Martinez, Fernando J; Salvatore, Steven P; Borczuk, Alain; Tata, Purushothama R; Sontake, Vishwaraj; Kimple, Adam; Jaspers, Ilona; O'Neal, Wanda K; Randell, Scott H; Boucher, Richard C; Baric, Ralph S.

Cell; 182(2): 429-446.e14, 2020 07 23.

Artículo en Inglés | MEDLINE | ID: mdl-32526206

2.

Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.

Wiehe, Kevin; Easterhoff, David; Luo, Kan; Nicely, Nathan I; Bradley, Todd; Jaeger, Frederick H; Dennison, S Moses; Zhang, Ruijun; Lloyd, Krissey E; Stolarchuk, Christina; Parks, Robert; Sutherland, Laura L; Scearce, Richard M; Morris, Lynn; Kaewkungwal, Jaranit; Nitayaphan, Sorachai; Pitisuttithum, Punnee; Rerks-Ngarm, Supachai; Sinangil, Faruk; Phogat, Sanjay; Michael, Nelson L; Kim, Jerome H; Kelsoe, Garnett; Montefiori, David C; Tomaras, Georgia D; Bonsignori, Mattia; Santra, Sampa; Kepler, Thomas B; Alam, S Munir; Moody, M Anthony; Liao, Hua-Xin; Haynes, Barton F.

Immunity; 41(6): 909-18, 2014 Dec 18.

Artículo en Inglés | MEDLINE | ID: mdl-25526306

3.

Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2.

Liao, Hua-Xin; Bonsignori, Mattia; Alam, S Munir; McLellan, Jason S; Tomaras, Georgia D; Moody, M Anthony; Kozink, Daniel M; Hwang, Kwan-Ki; Chen, Xi; Tsao, Chun-Yen; Liu, Pinghuang; Lu, Xiaozhi; Parks, Robert J; Montefiori, David C; Ferrari, Guido; Pollara, Justin; Rao, Mangala; Peachman, Kristina K; Santra, Sampa; Letvin, Norman L; Karasavvas, Nicos; Yang, Zhi-Yong; Dai, Kaifan; Pancera, Marie; Gorman, Jason; Wiehe, Kevin; Nicely, Nathan I; Rerks-Ngarm, Supachai; Nitayaphan, Sorachai; Kaewkungwal, Jaranit; Pitisuttithum, Punnee; Tartaglia, James; Sinangil, Faruk; Kim, Jerome H; Michael, Nelson L; Kepler, Thomas B; Kwong, Peter D; Mascola, John R; Nabel, Gary J; Pinter, Abraham; Zolla-Pazner, Susan; Haynes, Barton F.

Immunity; 38(1): 176-86, 2013 Jan 24.

Artículo en Inglés | MEDLINE | ID: mdl-23313589

4.

Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans.

Wu, Nelson R; Nicely, Nathan I; Lee, Esther M; Reed, Rachel K; Watts, Brian E; Cai, Fangping; Walkowicz, William E; Aussedat, Baptiste; Jones, Julia A; Eaton, Amanda; Trama, Ashley M; Alam, S Munir; Montefiori, David C; Haynes, Barton F; Saunders, Kevin O.

PLoS Pathog; 15(12): e1008165, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31841553

5.

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.

Wiehe, Kevin; Nicely, Nathan I; Lockwood, Bradley; Kuraoka, Masayuki; Anasti, Kara; Arora, Sabrina; Bowman, Cindy M; Stolarchuk, Christina; Parks, Robert; Lloyd, Krissey E; Xia, Shi-Mao; Duffy, Ryan; Shen, Xiaoying; Kyratsous, Christos A; Macdonald, Lynn E; Murphy, Andrew J; Scearce, Richard M; Moody, M Anthony; Alam, S Munir; Verkoczy, Laurent; Tomaras, Georgia D; Kelsoe, Garnett; Haynes, Barton F.

J Immunol; 198(3): 1047-1055, 2017 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-28011932

6.

Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys.

Nguyen, Quang N; Martinez, David R; Himes, Jonathon E; Whitney Edwards, R; Han, Qifeng; Kumar, Amit; Mangan, Riley; Nicely, Nathan I; Xie, Guanhua; Vandergrift, Nathan; Shen, Xiaoying; Pollara, Justin; Permar, Sallie R.

Retrovirology; 15(1): 24, 2018 Mar 09.

Artículo en Inglés | MEDLINE | ID: mdl-29523166

7.

Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk.

Martinez, David R; Vandergrift, Nathan; Douglas, Ayooluwa O; McGuire, Erin; Bainbridge, John; Nicely, Nathan I; Montefiori, David C; Tomaras, Georgia D; Fouda, Genevieve G; Permar, Sallie R.

J Virol; 91(9)2017 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-28202762

8.

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.

Santra, Sampa; Tomaras, Georgia D; Warrier, Ranjit; Nicely, Nathan I; Liao, Hua-Xin; Pollara, Justin; Liu, Pinghuang; Alam, S Munir; Zhang, Ruijun; Cocklin, Sarah L; Shen, Xiaoying; Duffy, Ryan; Xia, Shi-Mao; Schutte, Robert J; Pemble Iv, Charles W; Dennison, S Moses; Li, Hui; Chao, Andrew; Vidnovic, Kora; Evans, Abbey; Klein, Katja; Kumar, Amit; Robinson, James; Landucci, Gary; Forthal, Donald N; Montefiori, David C; Kaewkungwal, Jaranit; Nitayaphan, Sorachai; Pitisuttithum, Punnee; Rerks-Ngarm, Supachai; Robb, Merlin L; Michael, Nelson L; Kim, Jerome H; Soderberg, Kelly A; Giorgi, Elena E; Blair, Lily; Korber, Bette T; Moog, Christiane; Shattock, Robin J; Letvin, Norman L; Schmitz, Joern E; Moody, M A; Gao, Feng; Ferrari, Guido; Shaw, George M; Haynes, Barton F.

PLoS Pathog; 11(8): e1005042, 2015 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-26237403

9.

Polyreactivity and autoreactivity among HIV-1 antibodies.

Liu, Mengfei; Yang, Guang; Wiehe, Kevin; Nicely, Nathan I; Vandergrift, Nathan A; Rountree, Wes; Bonsignori, Mattia; Alam, S Munir; Gao, Jingyun; Haynes, Barton F; Kelsoe, Garnett.

J Virol; 89(1): 784-98, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25355869

10.

cis-Proline-mediated Ser(P)5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72.

Werner-Allen, Jon W; Lee, Chul-Jin; Liu, Pengda; Nicely, Nathan I; Wang, Su; Greenleaf, Arno L; Zhou, Pei.

J Biol Chem; 286(7): 5717-26, 2011 Feb 18.

Artículo en Inglés | MEDLINE | ID: mdl-21159777

11.

Maternal Broadly Neutralizing Antibodies Can Select for Neutralization-Resistant, Infant-Transmitted/Founder HIV Variants.

Martinez, David R; Tu, Joshua J; Kumar, Amit; Mangold, Jesse F; Mangan, Riley J; Goswami, Ria; Giorgi, Elena E; Chen, Juilin; Mengual, Michael; Douglas, Ayooluwa O; Heimsath, Holly; Saunders, Kevin O; Nicely, Nathan I; Eudailey, Joshua; Hernandez, Giovanna; Morgan-Asiedu, Papa Kwadwo; Wiehe, Kevin; Haynes, Barton F; Moody, M Anthony; LaBranche, Celia; Montefiori, David C; Gao, Feng; Permar, Sallie R.

mBio; 11(2)2020 03 10.

Artículo en Inglés | MEDLINE | ID: mdl-32156815

12.

Nucleoside triphosphate mimicry: a sugar triazolyl nucleoside as an ATP-competitive inhibitor of B. anthracis pantothenate kinase.

Rowan, Andrew S; Nicely, Nathan I; Cochrane, Nicola; Wlassoff, Wjatschesslaw A; Claiborne, Al; Hamilton, Chris J.

Org Biomol Chem; 7(19): 4029-36, 2009 Oct 07.

Artículo en Inglés | MEDLINE | ID: mdl-19763307

13.

Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.

Han, Qifeng; Jones, Julia A; Nicely, Nathan I; Reed, Rachel K; Shen, Xiaoying; Mansouri, Katayoun; Louder, Mark; Trama, Ashley M; Alam, S Munir; Edwards, Robert J; Bonsignori, Mattia; Tomaras, Georgia D; Korber, Bette; Montefiori, David C; Mascola, John R; Seaman, Michael S; Haynes, Barton F; Saunders, Kevin O.

Nat Commun; 10(1): 2898, 2019 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-31263112

14.

Rapid folding and unfolding of Apaf-1 CARD.

Milam, Sara L; Nicely, Nathan I; Feeney, Brett; Mattos, Carla; Clark, A Clay.

J Mol Biol; 369(1): 290-304, 2007 May 25.

Artículo en Inglés | MEDLINE | ID: mdl-17408690

15.

Phosphorylation of Aspergillus fumigatus PkaR impacts growth and cell wall integrity through novel mechanisms.

Shwab, Elliot K; Juvvadi, Praveen R; Waitt, Greg; Soderblom, Erik J; Moseley, Martin A; Nicely, Nathan I; Steinbach, William J.

FEBS Lett; 591(22): 3730-3744, 2017 11.

Artículo en Inglés | MEDLINE | ID: mdl-29067690

16.

A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus.

Shwab, E Keats; Juvvadi, Praveen R; Waitt, Greg; Soderblom, Erik J; Moseley, M Arthur; Nicely, Nathan I; Asfaw, Yohannes G; Steinbach, William J.

mBio; 8(1)2017 02 07.

Artículo en Inglés | MEDLINE | ID: mdl-28174315

17.

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.

Williams, LaTonya D; Ofek, Gilad; Schätzle, Sebastian; McDaniel, Jonathan R; Lu, Xiaozhi; Nicely, Nathan I; Wu, Liming; Lougheed, Caleb S; Bradley, Todd; Louder, Mark K; McKee, Krisha; Bailer, Robert T; O'Dell, Sijy; Georgiev, Ivelin S; Seaman, Michael S; Parks, Robert J; Marshall, Dawn J; Anasti, Kara; Yang, Guang; Nie, Xiaoyan; Tumba, Nancy L; Wiehe, Kevin; Wagh, Kshitij; Korber, Bette; Kepler, Thomas B; Munir Alam, S; Morris, Lynn; Kamanga, Gift; Cohen, Myron S; Bonsignori, Mattia; Xia, Shi-Mao; Montefiori, David C; Kelsoe, Garnett; Gao, Feng; Mascola, John R; Moody, M Anthony; Saunders, Kevin O; Liao, Hua-Xin; Tomaras, Georgia D; Georgiou, George; Haynes, Barton F.

Sci Immunol; 2(7)2017 Jan 27.

Artículo en Inglés | MEDLINE | ID: mdl-28783671

18.

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.

Saunders, Kevin O; Nicely, Nathan I; Wiehe, Kevin; Bonsignori, Mattia; Meyerhoff, R Ryan; Parks, Robert; Walkowicz, William E; Aussedat, Baptiste; Wu, Nelson R; Cai, Fangping; Vohra, Yusuf; Park, Peter K; Eaton, Amanda; Go, Eden P; Sutherland, Laura L; Scearce, Richard M; Barouch, Dan H; Zhang, Ruijun; Von Holle, Tarra; Overman, R Glenn; Anasti, Kara; Sanders, Rogier W; Moody, M Anthony; Kepler, Thomas B; Korber, Bette; Desaire, Heather; Santra, Sampa; Letvin, Norman L; Nabel, Gary J; Montefiori, David C; Tomaras, Georgia D; Liao, Hua-Xin; Alam, S Munir; Danishefsky, Samuel J; Haynes, Barton F.

Cell Rep; 18(9): 2175-2188, 2017 02 28.

Artículo en Inglés | MEDLINE | ID: mdl-28249163

19.

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.

Williams, Wilton B; Zhang, Jinsong; Jiang, Chuancang; Nicely, Nathan I; Fera, Daniela; Luo, Kan; Moody, M Anthony; Liao, Hua-Xin; Alam, S Munir; Kepler, Thomas B; Ramesh, Akshaya; Wiehe, Kevin; Holland, James A; Bradley, Todd; Vandergrift, Nathan; Saunders, Kevin O; Parks, Robert; Foulger, Andrew; Xia, Shi-Mao; Bonsignori, Mattia; Montefiori, David C; Louder, Mark; Eaton, Amanda; Santra, Sampa; Scearce, Richard; Sutherland, Laura; Newman, Amanda; Bouton-Verville, Hilary; Bowman, Cindy; Bomze, Howard; Gao, Feng; Marshall, Dawn J; Whitesides, John F; Nie, Xiaoyan; Kelsoe, Garnett; Reed, Steven G; Fox, Christopher B; Clary, Kim; Koutsoukos, Marguerite; Franco, David; Mascola, John R; Harrison, Stephen C; Haynes, Barton F; Verkoczy, Laurent.

Nat Commun; 8(1): 1732, 2017 11 23.

Artículo en Inglés | MEDLINE | ID: mdl-29170366

20.

Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap.

Nicely, Nathan I; Kosak, Justin; de Serrano, Vesna; Mattos, Carla.

Structure; 12(11): 2025-36, 2004 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-15530367

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