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1.

Genetic engineering of T cells for immunotherapy.

Ellis, Gavin I; Sheppard, Neil C; Riley, James L.

Nat Rev Genet; 2021 Feb 18.

Artículo en Inglés | MEDLINE | ID: mdl-33603158

2.

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation.

Beyer, Marc; Thabet, Yasser; Müller, Roman-Ulrich; Sadlon, Timothy; Classen, Sabine; Lahl, Katharina; Basu, Samik; Zhou, Xuyu; Bailey-Bucktrout, Samantha L; Krebs, Wolfgang; Schönfeld, Eva A; Böttcher, Jan; Golovina, Tatiana; Mayer, Christian T; Hofmann, Andrea; Sommer, Daniel; Debey-Pascher, Svenja; Endl, Elmar; Limmer, Andreas; Hippen, Keli L; Blazar, Bruce R; Balderas, Robert; Quast, Thomas; Waha, Andreas; Mayer, Günter; Famulok, Michael; Knolle, Percy A; Wickenhauser, Claudia; Kolanus, Waldemar; Schermer, Bernhard; Bluestone, Jeffrey A; Barry, Simon C; Sparwasser, Tim; Riley, James L; Schultze, Joachim L.

Nat Immunol; 12(9): 898-907, 2011 Aug 14.

Artículo en Inglés | MEDLINE | ID: mdl-21841785

3.

Selective reactivation of STING signaling to target Merkel cell carcinoma.

Liu, Wei; Kim, Gloria B; Krump, Nathan A; Zhou, Yuqi; Riley, James L; You, Jianxin.

Proc Natl Acad Sci U S A; 117(24): 13730-13739, 2020 06 16.

Artículo en Inglés | MEDLINE | ID: mdl-32482869

4.

Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates.

Rust, Blake J; Kean, Leslie S; Colonna, Lucrezia; Brandenstein, Katherine E; Poole, Nikhita H; Obenza, Willimark; Enstrom, Mark R; Maldini, Colby R; Ellis, Gavin I; Fennessey, Christine M; Huang, Meei-Li; Keele, Brandon F; Jerome, Keith R; Riley, James L; Kiem, Hans-Peter; Peterson, Christopher W.

Blood; 136(15): 1722-1734, 2020 Oct 08.

Artículo en Inglés | MEDLINE | ID: mdl-32614969

5.

Challenges and Opportunities of Using Adoptive T-Cell Therapy as Part of an HIV Cure Strategy.

Zhou, Yuqi; Maldini, Colby R; Jadlowsky, Julie; Riley, James L.

J Infect Dis; 223(Supplement_1): 38-45, 2021 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-33586770

6.

HIV-Resistant and HIV-Specific CAR-Modified CD4⁺ T Cells Mitigate HIV Disease Progression and Confer CD4⁺ T Cell Help In Vivo.

Maldini, Colby R; Gayout, Kevin; Leibman, Rachel S; Dopkin, Derrick L; Mills, Joshua P; Shan, Xiaochuan; Glover, Joshua A; Riley, James L.

Mol Ther; 28(7): 1585-1599, 2020 07 08.

Artículo en Inglés | MEDLINE | ID: mdl-32454027

7.

Role of PD-1 during effector CD8 T cell differentiation.

Ahn, Eunseon; Araki, Koichi; Hashimoto, Masao; Li, Weiyan; Riley, James L; Cheung, Jeanne; Sharpe, Arlene H; Freeman, Gordon J; Irving, Bryan A; Ahmed, Rafi.

Proc Natl Acad Sci U S A; 115(18): 4749-4754, 2018 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-29654146

8.

Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.

Youngblood, Ben; Oestreich, Kenneth J; Ha, Sang-Jun; Duraiswamy, Jaikumar; Akondy, Rama S; West, Erin E; Wei, Zhengyu; Lu, Peiyuan; Austin, James W; Riley, James L; Boss, Jeremy M; Ahmed, Rafi.

Immunity; 35(3): 400-12, 2011 Sep 23.

Artículo en Inglés | MEDLINE | ID: mdl-21943489

9.

Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.

Leibman, Rachel S; Richardson, Max W; Ellebrecht, Christoph T; Maldini, Colby R; Glover, Joshua A; Secreto, Anthony J; Kulikovskaya, Irina; Lacey, Simon F; Akkina, Sarah R; Yi, Yanjie; Shaheen, Farida; Wang, Jianbin; Dufendach, Keith A; Holmes, Michael C; Collman, Ronald G; Payne, Aimee S; Riley, James L.

PLoS Pathog; 13(10): e1006613, 2017 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-29023549

10.

Modulation of Hepatitis C Virus-Specific CD8 Effector T-Cell Function with Antiviral Effect in Infectious Hepatitis C Virus Coculture Model.

Ojiro, Keisuke; Qu, Xiaowang; Cho, Hyosun; Park, Jang-June; Vuidepot, Annelise; Lissin, Nikolai; Molloy, Peter E; Bennett, Alan; Jakobsen, Bent K; Kaplan, David E; Riley, James L; Chang, Kyong-Mi.

J Virol; 91(10)2017 05 15.

Artículo en Inglés | MEDLINE | ID: mdl-28275182

11.

Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus.

Leslie, George J; Wang, Jianbin; Richardson, Max W; Haggarty, Beth S; Hua, Kevin L; Duong, Jennifer; Secreto, Anthony J; Jordon, Andrea P O; Romano, Josephine; Kumar, Kritika E; DeClercq, Joshua J; Gregory, Philip D; June, Carl H; Root, Michael J; Riley, James L; Holmes, Michael C; Hoxie, James A.

PLoS Pathog; 12(11): e1005983, 2016 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-27855210

12.

miR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency.

Lu, Yunjie; Hippen, Keli L; Lemire, Amanda L; Gu, Jian; Wang, Weizhi; Ni, Xuhao; Ranganathan, Parvathi; Levine, Bruce L; Riley, James L; June, Carl H; Turka, Laurence A; Munn, David H; Garzon, Ramiro; Lu, Ling; Blazar, Bruce R.

Blood; 128(10): 1424-35, 2016 09 08.

Artículo en Inglés | MEDLINE | ID: mdl-27485827

13.

Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect.

Brunstein, Claudio G; Miller, Jeffrey S; McKenna, David H; Hippen, Keli L; DeFor, Todd E; Sumstad, Darin; Curtsinger, Julie; Verneris, Michael R; MacMillan, Margaret L; Levine, Bruce L; Riley, James L; June, Carl H; Le, Chap; Weisdorf, Daniel J; McGlave, Philip B; Blazar, Bruce R; Wagner, John E.

Blood; 127(8): 1044-51, 2016 Feb 25.

Artículo en Inglés | MEDLINE | ID: mdl-26563133

14.

Human T regulatory cell therapy: take a billion or so and call me in the morning.

Riley, James L; June, Carl H; Blazar, Bruce R.

Immunity; 30(5): 656-65, 2009 May.

Artículo en Inglés | MEDLINE | ID: mdl-19464988

15.

Cell-Mediated Immunity to Target the Persistent Human Immunodeficiency Virus Reservoir.

Riley, James L; Montaner, Luis J.

J Infect Dis; 215(suppl_3): S160-S171, 2017 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-28520969

16.

Generation of human islet-specific regulatory T cells by TCR gene transfer.

Hull, Caroline M; Nickolay, Lauren E; Estorninho, Megan; Richardson, Max W; Riley, James L; Peakman, Mark; Maher, John; Tree, Timothy I M.

J Autoimmun; 79: 63-73, 2017 May.

Artículo en Inglés | MEDLINE | ID: mdl-28117148

17.

Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials.

McKenna, David H; Sumstad, Darin; Kadidlo, Diane M; Batdorf, Bjorn; Lord, Colin J; Merkel, Sarah C; Koellner, Christine M; Curtsinger, Julie M; June, Carl H; Riley, James L; Levine, Bruce L; Miller, Jeffrey S; Brunstein, Claudio G; Wagner, John E; Blazar, Bruce R; Hippen, Keli L.

Cytotherapy; 19(2): 250-262, 2017 02.

Artículo en Inglés | MEDLINE | ID: mdl-27887864

18.

Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection.

Didigu, Chuka A; Wilen, Craig B; Wang, Jianbin; Duong, Jennifer; Secreto, Anthony J; Danet-Desnoyers, Gwenn A; Riley, James L; Gregory, Phillip D; June, Carl H; Holmes, Michael C; Doms, Robert W.

Blood; 123(1): 61-9, 2014 Jan 02.

Artículo en Inglés | MEDLINE | ID: mdl-24162716

19.

Cutaneous T cell lymphoma expresses immunosuppressive CD80 (B7-1) cell surface protein in a STAT5-dependent manner.

Zhang, Qian; Wang, Hong Yi; Wei, Fang; Liu, Xiaobin; Paterson, Jennifer C; Roy, Darshan; Mihova, Daniela; Woetmann, Anders; Ptasznik, Andrzej; Odum, Niels; Schuster, Stephen J; Marafioti, Teresa; Riley, James L; Wasik, Mariusz A.

J Immunol; 192(6): 2913-9, 2014 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-24523507

20.

Engineering T Cells to Functionally Cure HIV-1 Infection.

Leibman, Rachel S; Riley, James L.

Mol Ther; 23(7): 1149-1159, 2015 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-25896251

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