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1.

Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.

Thomson, Emma C; Rosen, Laura E; Shepherd, James G; Spreafico, Roberto; da Silva Filipe, Ana; Wojcechowskyj, Jason A; Davis, Chris; Piccoli, Luca; Pascall, David J; Dillen, Josh; Lytras, Spyros; Czudnochowski, Nadine; Shah, Rajiv; Meury, Marcel; Jesudason, Natasha; De Marco, Anna; Li, Kathy; Bassi, Jessica; O'Toole, Aine; Pinto, Dora; Colquhoun, Rachel M; Culap, Katja; Jackson, Ben; Zatta, Fabrizia; Rambaut, Andrew; Jaconi, Stefano; Sreenu, Vattipally B; Nix, Jay; Zhang, Ivy; Jarrett, Ruth F; Glass, William G; Beltramello, Martina; Nomikou, Kyriaki; Pizzuto, Matteo; Tong, Lily; Cameroni, Elisabetta; Croll, Tristan I; Johnson, Natasha; Di Iulio, Julia; Wickenhagen, Arthur; Ceschi, Alessandro; Harbison, Aoife M; Mair, Daniel; Ferrari, Paolo; Smollett, Katherine; Sallusto, Federica; Carmichael, Stephen; Garzoni, Christian; Nichols, Jenna; Galli, Massimo.

Cell; 184(5): 1171-1187.e20, 2021 03 04.

Artículo en Inglés | MEDLINE | ID: mdl-33621484

2.

Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation.

Di Gioia, Marco; Spreafico, Roberto; Springstead, James R; Mendelson, Michael M; Joehanes, Roby; Levy, Daniel; Zanoni, Ivan.

Nat Immunol; 21(1): 42-53, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31768073

3.

A perspective on potential antibody-dependent enhancement of SARS-CoV-2.

Arvin, Ann M; Fink, Katja; Schmid, Michael A; Cathcart, Andrea; Spreafico, Roberto; Havenar-Daughton, Colin; Lanzavecchia, Antonio; Corti, Davide; Virgin, Herbert W.

Nature; 584(7821): 353-363, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32659783

4.

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

Pinto, Dora; Park, Young-Jun; Beltramello, Martina; Walls, Alexandra C; Tortorici, M Alejandra; Bianchi, Siro; Jaconi, Stefano; Culap, Katja; Zatta, Fabrizia; De Marco, Anna; Peter, Alessia; Guarino, Barbara; Spreafico, Roberto; Cameroni, Elisabetta; Case, James Brett; Chen, Rita E; Havenar-Daughton, Colin; Snell, Gyorgy; Telenti, Amalio; Virgin, Herbert W; Lanzavecchia, Antonio; Diamond, Michael S; Fink, Katja; Veesler, David; Corti, Davide.

Nature; 583(7815): 290-295, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32422645

5.

PGRMC2 is an intracellular haem chaperone critical for adipocyte function.

Galmozzi, Andrea; Kok, Bernard P; Kim, Arthur S; Montenegro-Burke, J Rafael; Lee, Jae Y; Spreafico, Roberto; Mosure, Sarah; Albert, Verena; Cintron-Colon, Rigo; Godio, Cristina; Webb, William R; Conti, Bruno; Solt, Laura A; Kojetin, Douglas; Parker, Christopher G; Peluso, John J; Pru, James K; Siuzdak, Gary; Cravatt, Benjamin F; Saez, Enrique.

Nature; 576(7785): 138-142, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31748741

6.

The histone variant H2A.Z promotes efficient cotranscriptional splicing in S. cerevisiae.

Neves, Lauren T; Douglass, Stephen; Spreafico, Roberto; Venkataramanan, Srivats; Kress, Tracy L; Johnson, Tracy L.

Genes Dev; 31(7): 702-717, 2017 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-28446598

7.

Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor.

Mognol, Giuliana P; González-Avalos, Edahí; Ghosh, Srimoyee; Spreafico, Roberto; Gudlur, Aparna; Rao, Anjana; Damoiseaux, Robert; Hogan, Patrick G.

Proc Natl Acad Sci U S A; 116(20): 9959-9968, 2019 05 14.

Artículo en Inglés | MEDLINE | ID: mdl-31019078

8.

Dendritic pathology, spine loss and synaptic reorganization in human cortex from epilepsy patients.

Rossini, Laura; De Santis, Dalia; Mauceri, Roberta Rosa; Tesoriero, Chiara; Bentivoglio, Marina; Maderna, Emanuela; Maiorana, Antonio; Deleo, Francesco; de Curtis, Marco; Tringali, Giovanni; Cossu, Massimo; Tumminelli, Gemma; Bramerio, Manuela; Spreafico, Roberto; Tassi, Laura; Garbelli, Rita.

Brain; 2020 Nov 22.

Artículo en Inglés | MEDLINE | ID: mdl-33221837

9.

Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery.

Blumcke, Ingmar; Spreafico, Roberto; Haaker, Gerrit; Coras, Roland; Kobow, Katja; Bien, Christian G; Pfäfflin, Margarete; Elger, Christian; Widman, Guido; Schramm, Johannes; Becker, Albert; Braun, Kees P; Leijten, Frans; Baayen, Johannes C; Aronica, Eleonora; Chassoux, Francine; Hamer, Hajo; Stefan, Hermann; Rössler, Karl; Thom, Maria; Walker, Matthew C; Sisodiya, Sanjay M; Duncan, John S; McEvoy, Andrew W; Pieper, Tom; Holthausen, Hans; Kudernatsch, Manfred; Meencke, H Joachim; Kahane, Philippe; Schulze-Bonhage, Andreas; Zentner, Josef; Heiland, Dieter H; Urbach, Horst; Steinhoff, Bernhard J; Bast, Thomas; Tassi, Laura; Lo Russo, Giorgio; Özkara, Cigdem; Oz, Buge; Krsek, Pavel; Vogelgesang, Silke; Runge, Uwe; Lerche, Holger; Weber, Yvonne; Honavar, Mrinalini; Pimentel, José; Arzimanoglou, Alexis; Ulate-Campos, Adriana; Noachtar, Soheyl; Hartl, Elisabeth.

N Engl J Med; 377(17): 1648-1656, 2017 10 26.

Artículo en Inglés | MEDLINE | ID: mdl-29069555

10.

pCREB expression in human tissues from epilepsy surgery.

De Santis, Dalia; Rossini, Laura; Tassi, Laura; Didato, Giuseppe; Tringali, Giovanni; Cossu, Massimo; Bramerio, Manuela; Padelli, Francesco; Regondi, Maria Cristina; Colciaghi, Francesca; Aronica, Eleonora; Spreafico, Roberto; Garbelli, Rita.

Epilepsia; 61(6): 1240-1252, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32463128

11.

Drebrin expression patterns in patients with refractory temporal lobe epilepsy and hippocampal sclerosis.

Dombroski, Thaís Caroline Dallabona; Peixoto-Santos, Jose Eduardo; Maciel, Karina; Baqui, Munira Muhammad Abdel; Velasco, Tonicarlo Rodrigues; Sakamoto, Americo Ceiki; Assirati, João Alberto; Carlotti, Carlos Gilberto; Machado, Hélio Rubens; Sousa, Gleice Kelly de; Hanamura, Kenji; Leite, João Pereira; Costa da Costa, Jaderson; Palmini, André Luiz; Paglioli, Eliseu; Neder, Luciano; Spreafico, Roberto; Shirao, Tomoaki; Garbelli, Rita; Martins, Antonio Roberto.

Epilepsia; 61(8): 1581-1594, 2020 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-32662890

12.

Exhaustion-associated regulatory regions in CD8⁺ tumor-infiltrating T cells.

Mognol, Giuliana P; Spreafico, Roberto; Wong, Victor; Scott-Browne, James P; Togher, Susan; Hoffmann, Alexander; Hogan, Patrick G; Rao, Anjana; Trifari, Sara.

Proc Natl Acad Sci U S A; 114(13): E2776-E2785, 2017 03 28.

Artículo en Inglés | MEDLINE | ID: mdl-28283662

13.

Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense.

Scumpia, Philip O; Botten, Giovanni A; Norman, Joshua S; Kelly-Scumpia, Kindra M; Spreafico, Roberto; Ruccia, Amber R; Purbey, Prabhat K; Thomas, Brandon J; Modlin, Robert L; Smale, Stephen T.

PLoS Pathog; 13(7): e1006496, 2017 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-28704551

14.

The Syk-NFAT-IL-2 Pathway in Dendritic Cells Is Required for Optimal Sterile Immunity Elicited by Alum Adjuvants.

Khameneh, Hanif Javanmard; Ho, Adrian W S; Spreafico, Roberto; Derks, Heidi; Quek, Hazel Q Y; Mortellaro, Alessandra.

J Immunol; 198(1): 196-204, 2017 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-27895176

15.

Epipolymorphisms associated with the clinical outcome of autoimmune arthritis affect CD4+ T cell activation pathways.

Spreafico, Roberto; Rossetti, Maura; Whitaker, John W; Wang, Wei; Lovell, Daniel J; Albani, Salvatore.

Proc Natl Acad Sci U S A; 113(48): 13845-13850, 2016 11 29.

Artículo en Inglés | MEDLINE | ID: mdl-27849614

16.

Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei.

Langousis, Gerasimos; Shimogawa, Michelle M; Saada, Edwin A; Vashisht, Ajay A; Spreafico, Roberto; Nager, Andrew R; Barshop, William D; Nachury, Maxence V; Wohlschlegel, James A; Hill, Kent L.

Proc Natl Acad Sci U S A; 113(3): 632-7, 2016 Jan 19.

Artículo en Inglés | MEDLINE | ID: mdl-26721397

17.

Seizure activity per se does not induce tissue damage markers in human neocortical focal epilepsy.

Rossini, Laura; Garbelli, Rita; Gnatkovsky, Vadym; Didato, Giuseppe; Villani, Flavio; Spreafico, Roberto; Deleo, Francesco; Lo Russo, Giorgio; Tringali, Giovanni; Gozzo, Francesca; Tassi, Laura; de Curtis, Marco.

Ann Neurol; 82(3): 331-341, 2017 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-28749594

18.

Training the 21st Century Immunologist.

Spreafico, Roberto; Mitchell, Simon; Hoffmann, Alexander.

Trends Immunol; 36(5): 283-5, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25911462

19.

Increased autophagy in CD4⁺ T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance.

van Loosdregt, Jorg; Rossetti, Maura; Spreafico, Roberto; Moshref, Maryam; Olmer, Merissa; Williams, Gary W; Kumar, Pavanish; Copeland, Dana; Pischel, Ken; Lotz, Martin; Albani, Salvatore.

Eur J Immunol; 46(12): 2862-2870, 2016 12.

Artículo en Inglés | MEDLINE | ID: mdl-27624289

20.

TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis.

Rossetti, Maura; Spreafico, Roberto; Consolaro, Alessandro; Leong, Jing Yao; Chua, Camillus; Massa, Margherita; Saidin, Suzan; Magni-Manzoni, Silvia; Arkachaisri, Thaschawee; Wallace, Carol A; Gattorno, Marco; Martini, Alberto; Lovell, Daniel J; Albani, Salvatore.

Ann Rheum Dis; 76(2): 435-441, 2017 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-27311837

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