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1.

TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.

Ho, Jessica Sook Yuin; Mok, Bobo Wing-Yee; Campisi, Laura; Jordan, Tristan; Yildiz, Soner; Parameswaran, Sreeja; Wayman, Joseph A; Gaudreault, Natasha N; Meekins, David A; Indran, Sabarish V; Morozov, Igor; Trujillo, Jessie D; Fstkchyan, Yesai S; Rathnasinghe, Raveen; Zhu, Zeyu; Zheng, Simin; Zhao, Nan; White, Kris; Ray-Jones, Helen; Malysheva, Valeriya; Thiecke, Michiel J; Lau, Siu-Ying; Liu, Honglian; Zhang, Anna Junxia; Lee, Andrew Chak-Yiu; Liu, Wen-Chun; Jangra, Sonia; Escalera, Alba; Aydillo, Teresa; Melo, Betsaida Salom; Guccione, Ernesto; Sebra, Robert; Shum, Elaine; Bakker, Jan; Kaufman, David A; Moreira, Andre L; Carossino, Mariano; Balasuriya, Udeni B R; Byun, Minji; Albrecht, Randy A; Schotsaert, Michael; Garcia-Sastre, Adolfo; Chanda, Sumit K; Miraldi, Emily R; Jeyasekharan, Anand D; TenOever, Benjamin R; Spivakov, Mikhail; Weirauch, Matthew T; Heinz, Sven; Chen, Honglin.

Cell; 2021 Mar 30.

Artículo en Inglés | MEDLINE | ID: mdl-33836156

2.

Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells.

Daniloski, Zharko; Jordan, Tristan X; Wessels, Hans-Hermann; Hoagland, Daisy A; Kasela, Silva; Legut, Mateusz; Maniatis, Silas; Mimitou, Eleni P; Lu, Lu; Geller, Evan; Danziger, Oded; Rosenberg, Brad R; Phatnani, Hemali; Smibert, Peter; Lappalainen, Tuuli; tenOever, Benjamin R; Sanjana, Neville E.

Cell; 2020 Oct 24.

Artículo en Inglés | MEDLINE | ID: mdl-33147445

3.

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.

Blanco-Melo, Daniel; Nilsson-Payant, Benjamin E; Liu, Wen-Chun; Uhl, Skyler; Hoagland, Daisy; Møller, Rasmus; Jordan, Tristan X; Oishi, Kohei; Panis, Maryline; Sachs, David; Wang, Taia T; Schwartz, Robert E; Lim, Jean K; Albrecht, Randy A; tenOever, Benjamin R.

Cell; 181(5): 1036-1045.e9, 2020 05 28.

Artículo en Inglés | MEDLINE | ID: mdl-32416070

4.

Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity.

Hoagland, Daisy A; Møller, Rasmus; Uhl, Skyler A; Oishi, Kohei; Frere, Justin; Golynker, Ilona; Horiuchi, Shu; Panis, Maryline; Blanco-Melo, Daniel; Sachs, David; Arkun, Knarik; Lim, Jean K; tenOever, Benjamin R.

Immunity; 54(3): 557-570.e5, 2021 03 09.

Artículo en Inglés | MEDLINE | ID: mdl-33577760

5.

Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense.

Moy, Ryan H; Cole, Brian S; Yasunaga, Ari; Gold, Beth; Shankarling, Ganesh; Varble, Andrew; Molleston, Jerome M; tenOever, Benjamin R; Lynch, Kristen W; Cherry, Sara.

Cell; 158(4): 764-777, 2014 Aug 14.

Artículo en Inglés | MEDLINE | ID: mdl-25126784

6.

Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.

Han, Yuling; Duan, Xiaohua; Yang, Liuliu; Nilsson-Payant, Benjamin E; Wang, Pengfei; Duan, Fuyu; Tang, Xuming; Yaron, Tomer M; Zhang, Tuo; Uhl, Skyler; Bram, Yaron; Richardson, Chanel; Zhu, Jiajun; Zhao, Zeping; Redmond, David; Houghton, Sean; Nguyen, Duc-Huy T; Xu, Dong; Wang, Xing; Jessurun, Jose; Borczuk, Alain; Huang, Yaoxing; Johnson, Jared L; Liu, Yuru; Xiang, Jenny; Wang, Hui; Cantley, Lewis C; tenOever, Benjamin R; Ho, David D; Pan, Fong Cheng; Evans, Todd; Chen, Huanhuan Joyce; Schwartz, Robert E; Chen, Shuibing.

Nature; 2020 Oct 28.

Artículo en Inglés | MEDLINE | ID: mdl-33116299

7.

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKÎµ kinase-mediated antiviral response.

Rajsbaum, Ricardo; Versteeg, Gijs A; Schmid, Sonja; Maestre, Ana M; Belicha-Villanueva, Alan; Martínez-Romero, Carles; Patel, Jenish R; Morrison, Juliet; Pisanelli, Giuseppe; Miorin, Lisa; Laurent-Rolle, Maudry; Moulton, Hong M; Stein, David A; Fernandez-Sesma, Ana; tenOever, Benjamin R; García-Sastre, Adolfo.

Immunity; 40(6): 880-95, 2014 Jun 19.

Artículo en Inglés | MEDLINE | ID: mdl-24882218

8.

RNase III nucleases from diverse kingdoms serve as antiviral effectors.

Aguado, Lauren C; Schmid, Sonja; May, Jared; Sabin, Leah R; Panis, Maryline; Blanco-Melo, Daniel; Shim, Jaehee V; Sachs, David; Cherry, Sara; Simon, Anne E; Levraud, Jean-Pierre; tenOever, Benjamin R.

Nature; 547(7661): 114-117, 2017 07 06.

Artículo en Inglés | MEDLINE | ID: mdl-28658212

9.

Reduced Nucleoprotein availability impairs negative-sense RNA virus replication and promotes host recognition.

Nilsson-Payant, Benjamin E; Blanco-Melo, Daniel; Uhl, Skyler; Escudero-Pérez, Beatriz; Olschewski, Silke; Thibault, Patricia; Panis, Maryline; Rosenthal, Maria; Muñoz-Fontela, César; Lee, Benhur; tenOever, Benjamin R.

J Virol; 2021 Feb 10.

Artículo en Inglés | MEDLINE | ID: mdl-33568513

10.

Type I interferon response impairs differentiation potential of pluripotent stem cells.

Eggenberger, Julie; Blanco-Melo, Daniel; Panis, Maryline; Brennand, Kristen J; tenOever, Benjamin R.

Proc Natl Acad Sci U S A; 116(4): 1384-1393, 2019 01 22.

Artículo en Inglés | MEDLINE | ID: mdl-30606801

11.

Rapid Dissemination and Monopolization of Viral Populations in Mice Revealed Using a Panel of Barcoded Viruses.

McCune, Broc T; Lanahan, Matthew R; tenOever, Benjamin R; Pfeiffer, Julie K.

J Virol; 94(2)2020 01 06.

Artículo en Inglés | MEDLINE | ID: mdl-31666382

12.

miRNA-mediated targeting of human cytomegalovirus reveals biological host and viral targets of IE2.

Møller, Rasmus; Schwarz, Toni M; Noriega, Vanessa M; Panis, Maryline; Sachs, David; Tortorella, Domenico; tenOever, Benjamin R.

Proc Natl Acad Sci U S A; 115(5): 1069-1074, 2018 01 30.

Artículo en Inglés | MEDLINE | ID: mdl-29339472

13.

Homologous recombination is an intrinsic defense against antiviral RNA interference.

Aguado, Lauren C; Jordan, Tristan X; Hsieh, Emily; Blanco-Melo, Daniel; Heard, John; Panis, Maryline; Vignuzzi, Marco; tenOever, Benjamin R.

Proc Natl Acad Sci U S A; 115(39): E9211-E9219, 2018 09 25.

Artículo en Inglés | MEDLINE | ID: mdl-30209219

14.

RNase III Nucleases and the Evolution of Antiviral Systems.

Aguado, Lauren C; tenOever, Benjamin R.

Bioessays; 40(2)2018 02.

Artículo en Inglés | MEDLINE | ID: mdl-29266287

15.

Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model.

Duehr, James; Wohlbold, Teddy John; Oestereich, Lisa; Chromikova, Veronika; Amanat, Fatima; Rajendran, Madhusudan; Gomez-Medina, Sergio; Mena, Ignacio; tenOever, Benjamin R; García-Sastre, Adolfo; Basler, Christopher F; Munoz-Fontela, Cesar; Krammer, Florian.

J Virol; 91(16)2017 08 15.

Artículo en Inglés | MEDLINE | ID: mdl-28592526

16.

Drosha as an interferon-independent antiviral factor.

Shapiro, Jillian S; Schmid, Sonja; Aguado, Lauren C; Sabin, Leah R; Yasunaga, Ari; Shim, Jaehee V; Sachs, David; Cherry, Sara; tenOever, Benjamin R.

Proc Natl Acad Sci U S A; 111(19): 7108-13, 2014 May 13.

Artículo en Inglés | MEDLINE | ID: mdl-24778219

17.

Mitogen-activated protein kinase-mediated licensing of interferon regulatory factor 3/7 reinforces the cell response to virus.

Schmid, Sonja; Sachs, David; tenOever, Benjamin R.

J Biol Chem; 289(1): 299-311, 2014 Jan 03.

Artículo en Inglés | MEDLINE | ID: mdl-24275658

18.

A versatile RNA vector for delivery of coding and noncoding RNAs.

Schmid, Sonja; Zony, Lum C; tenOever, Benjamin R.

J Virol; 88(4): 2333-6, 2014 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-24307584

19.

Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses.

Langlois, Ryan A; Varble, Andrew; Chua, Mark A; García-Sastre, Adolfo; tenOever, Benjamin R.

Proc Natl Acad Sci U S A; 109(30): 12117-22, 2012 Jul 24.

Artículo en Inglés | MEDLINE | ID: mdl-22778433

20.

Evidence for a cytoplasmic microprocessor of pri-miRNAs.

Shapiro, Jillian S; Langlois, Ryan A; Pham, Alissa M; Tenoever, Benjamin R.

RNA; 18(7): 1338-46, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22635403

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