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1.

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein.

Walls, Alexandra C; Park, Young-Jun; Tortorici, M Alejandra; Wall, Abigail; McGuire, Andrew T; Veesler, David.

Cell; 181(2): 281-292.e6, 2020 04 16.

Artículo en Inglés | MEDLINE | ID: covidwho-5754

2.

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein.

Walls, Alexandra C; Park, Young-Jun; Tortorici, M Alejandra; Wall, Abigail; McGuire, Andrew T; Veesler, David.

Cell; 181(2): 281-292.e6, 2020 04 16.

Artículo en Inglés | MEDLINE | ID: mdl-32155444

3.

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.

Walls, Alexandra C; Xiong, Xiaoli; Park, Young-Jun; Tortorici, M Alejandra; Snijder, Joost; Quispe, Joel; Cameroni, Elisabetta; Gopal, Robin; Dai, Mian; Lanzavecchia, Antonio; Zambon, Maria; Rey, Félix A; Corti, Davide; Veesler, David.

Cell; 176(5): 1026-1039.e15, 2019 02 21.

Artículo en Inglés | MEDLINE | ID: mdl-30712865

4.

Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding.

Starr, Tyler N; Greaney, Allison J; Hilton, Sarah K; Ellis, Daniel; Crawford, Katharine H D; Dingens, Adam S; Navarro, Mary Jane; Bowen, John E; Tortorici, M Alejandra; Walls, Alexandra C; King, Neil P; Veesler, David; Bloom, Jesse D.

Cell; 182(5): 1295-1310.e20, 2020 09 03.

Artículo en Inglés | MEDLINE | ID: mdl-32841599

5.

Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2.

Walls, Alexandra C; Fiala, Brooke; Schäfer, Alexandra; Wrenn, Samuel; Pham, Minh N; Murphy, Michael; Tse, Longping V; Shehata, Laila; O'Connor, Megan A; Chen, Chengbo; Navarro, Mary Jane; Miranda, Marcos C; Pettie, Deleah; Ravichandran, Rashmi; Kraft, John C; Ogohara, Cassandra; Palser, Anne; Chalk, Sara; Lee, E-Chiang; Guerriero, Kathryn; Kepl, Elizabeth; Chow, Cameron M; Sydeman, Claire; Hodge, Edgar A; Brown, Brieann; Fuller, Jim T; Dinnon, Kenneth H; Gralinski, Lisa E; Leist, Sarah R; Gully, Kendra L; Lewis, Thomas B; Guttman, Miklos; Chu, Helen Y; Lee, Kelly K; Fuller, Deborah H; Baric, Ralph S; Kellam, Paul; Carter, Lauren; Pepper, Marion; Sheahan, Timothy P; Veesler, David; King, Neil P.

Cell; 183(5): 1367-1382.e17, 2020 11 25.

Artículo en Inglés | MEDLINE | ID: mdl-33160446

6.

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.

Piccoli, Luca; Park, Young-Jun; Tortorici, M Alejandra; Czudnochowski, Nadine; Walls, Alexandra C; Beltramello, Martina; Silacci-Fregni, Chiara; Pinto, Dora; Rosen, Laura E; Bowen, John E; Acton, Oliver J; Jaconi, Stefano; Guarino, Barbara; Minola, Andrea; Zatta, Fabrizia; Sprugasci, Nicole; Bassi, Jessica; Peter, Alessia; De Marco, Anna; Nix, Jay C; Mele, Federico; Jovic, Sandra; Rodriguez, Blanca Fernandez; Gupta, Sneha V; Jin, Feng; Piumatti, Giovanni; Lo Presti, Giorgia; Pellanda, Alessandra Franzetti; Biggiogero, Maira; Tarkowski, Maciej; Pizzuto, Matteo S; Cameroni, Elisabetta; Havenar-Daughton, Colin; Smithey, Megan; Hong, David; Lepori, Valentino; Albanese, Emiliano; Ceschi, Alessandro; Bernasconi, Enos; Elzi, Luigia; Ferrari, Paolo; Garzoni, Christian; Riva, Agostino; Snell, Gyorgy; Sallusto, Federica; Fink, Katja; Virgin, Herbert W; Lanzavecchia, Antonio; Corti, Davide; Veesler, David.

Cell; 183(4): 1024-1042.e21, 2020 11 12.

Artículo en Inglés | MEDLINE | ID: mdl-32991844

7.

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein.

Walls, Alexandra C; Park, Young-Jun; Tortorici, M Alejandra; Wall, Abigail; McGuire, Andrew T; Veesler, David.

Cell; 183(6): 1735, 2020 Dec 10.

Artículo en Inglés | MEDLINE | ID: mdl-33306958

8.

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.

Walls, Alexandra C; Xiong, Xiaoli; Park, Young-Jun; Tortorici, M Alejandra; Snijder, Joost; Quispe, Joel; Cameroni, Elisabetta; Gopal, Robin; Dai, Mian; Lanzavecchia, Antonio; Zambon, Maria; Rey, Félix A; Corti, Davide; Veesler, David.

Cell; 183(6): 1732, 2020 Dec 10.

Artículo en Inglés | MEDLINE | ID: mdl-33306956

9.

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

Pinto, Dora; Park, Young-Jun; Beltramello, Martina; Walls, Alexandra C; Tortorici, M Alejandra; Bianchi, Siro; Jaconi, Stefano; Culap, Katja; Zatta, Fabrizia; De Marco, Anna; Peter, Alessia; Guarino, Barbara; Spreafico, Roberto; Cameroni, Elisabetta; Case, James Brett; Chen, Rita E; Havenar-Daughton, Colin; Snell, Gyorgy; Telenti, Amalio; Virgin, Herbert W; Lanzavecchia, Antonio; Diamond, Michael S; Fink, Katja; Veesler, David; Corti, Davide.

Nature; 2020 May 18.

Artículo en Inglés | MEDLINE | ID: covidwho-291856

10.

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

Pinto, Dora; Park, Young-Jun; Beltramello, Martina; Walls, Alexandra C; Tortorici, M Alejandra; Bianchi, Siro; Jaconi, Stefano; Culap, Katja; Zatta, Fabrizia; De Marco, Anna; Peter, Alessia; Guarino, Barbara; Spreafico, Roberto; Cameroni, Elisabetta; Case, James Brett; Chen, Rita E; Havenar-Daughton, Colin; Snell, Gyorgy; Telenti, Amalio; Virgin, Herbert W; Lanzavecchia, Antonio; Diamond, Michael S; Fink, Katja; Veesler, David; Corti, Davide.

Nature; 583(7815): 290-295, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32422645

11.

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer.

Walls, Alexandra C; Tortorici, M Alejandra; Bosch, Berend-Jan; Frenz, Brandon; Rottier, Peter J M; DiMaio, Frank; Rey, Félix A; Veesler, David.

Nature; 531(7592): 114-117, 2016 Mar 03.

Artículo en Inglés | MEDLINE | ID: mdl-26855426

12.

RosettaES: a sampling strategy enabling automated interpretation of difficult cryo-EM maps.

Frenz, Brandon; Walls, Alexandra C; Egelman, Edward H; Veesler, David; DiMaio, Frank.

Nat Methods; 14(8): 797-800, 2017 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-28628127

13.

Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion.

Walls, Alexandra C; Tortorici, M Alejandra; Snijder, Joost; Xiong, Xiaoli; Bosch, Berend-Jan; Rey, Felix A; Veesler, David.

Proc Natl Acad Sci U S A; 114(42): 11157-11162, 2017 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-29073020

14.

Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections.

Xiong, Xiaoli; Tortorici, M Alejandra; Snijder, Joost; Yoshioka, Craig; Walls, Alexandra C; Li, Wentao; McGuire, Andrew T; Rey, Félix A; Bosch, Berend-Jan; Veesler, David.

J Virol; 92(4)2018 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-29093093

15.

Vitrification after multiple rounds of sample application and blotting improves particle density on cryo-electron microscopy grids.

Snijder, Joost; Borst, Andrew J; Dosey, Annie; Walls, Alexandra C; Burrell, Anika; Reddy, Vijay S; Kollman, Justin M; Veesler, David.

J Struct Biol; 198(1): 38-42, 2017 04.

Artículo en Inglés | MEDLINE | ID: mdl-28254381

16.

Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation.

McCallum, Matthew; Walls, Alexandra C; Bowen, John E; Corti, Davide; Veesler, David.

Nat Struct Mol Biol; 27(10): 942-949, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32753755

17.

Automatically Fixing Errors in Glycoprotein Structures with Rosetta.

Frenz, Brandon; Rämisch, Sebastian; Borst, Andrew J; Walls, Alexandra C; Adolf-Bryfogle, Jared; Schief, William R; Veesler, David; DiMaio, Frank.

Structure; 27(1): 134-139.e3, 2019 01 02.

Artículo en Inglés | MEDLINE | ID: mdl-30344107

18.

Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.

Park, Young-Jun; Walls, Alexandra C; Wang, Zhaoqian; Sauer, Maximillian M; Li, Wentao; Tortorici, M Alejandra; Bosch, Berend-Jan; DiMaio, Frank; Veesler, David.

Nat Struct Mol Biol; 26(12): 1151-1157, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31792450

19.

Structural basis for human coronavirus attachment to sialic acid receptors.

Tortorici, M Alejandra; Walls, Alexandra C; Lang, Yifei; Wang, Chunyan; Li, Zeshi; Koerhuis, Danielle; Boons, Geert-Jan; Bosch, Berend-Jan; Rey, Félix A; de Groot, Raoul J; Veesler, David.

Nat Struct Mol Biol; 26(6): 481-489, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-31160783

20.

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.

Cao, Longxing; Goreshnik, Inna; Coventry, Brian; Case, James Brett; Miller, Lauren; Kozodoy, Lisa; Chen, Rita E; Carter, Lauren; Walls, Alexandra C; Park, Young-Jun; Strauch, Eva-Maria; Stewart, Lance; Diamond, Michael S; Veesler, David; Baker, David.

Science; 370(6515): 426-431, 2020 10 23.

Artículo en Inglés | MEDLINE | ID: mdl-32907861

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Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein.

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein.

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.

Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding.

Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2.

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein.

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer.

RosettaES: a sampling strategy enabling automated interpretation of difficult cryo-EM maps.

Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion.

Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections.

Vitrification after multiple rounds of sample application and blotting improves particle density on cryo-electron microscopy grids.

Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation.

Automatically Fixing Errors in Glycoprotein Structures with Rosetta.

Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.

Structural basis for human coronavirus attachment to sialic acid receptors.

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.