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1.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Wrapp, Daniel; De Vlieger, Dorien; Corbett, Kizzmekia S; Torres, Gretel M; Wang, Nianshuang; Van Breedam, Wander; Roose, Kenny; van Schie, Loes; Hoffmann, Markus; Pöhlmann, Stefan; Graham, Barney S; Callewaert, Nico; Schepens, Bert; Saelens, Xavier; McLellan, Jason S.

Cell; 181(5): 1004-1015.e15, 2020 05 28.

Artículo en Inglés | MEDLINE | ID: covidwho-88549

2.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Wrapp, Daniel; De Vlieger, Dorien; Corbett, Kizzmekia S; Torres, Gretel M; Wang, Nianshuang; Van Breedam, Wander; Roose, Kenny; van Schie, Loes; Hoffmann, Markus; Pöhlmann, Stefan; Graham, Barney S; Callewaert, Nico; Schepens, Bert; Saelens, Xavier; McLellan, Jason S.

Cell; 181(5): 1004-1015.e15, 2020 05 28.

Artículo en Inglés | MEDLINE | ID: mdl-32375025

3.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Wrapp, Daniel; De Vlieger, Dorien; Corbett, Kizzmekia S; Torres, Gretel M; Wang, Nianshuang; Van Breedam, Wander; Roose, Kenny; van Schie, Loes; Hoffmann, Markus; Pöhlmann, Stefan; Graham, Barney S; Callewaert, Nico; Schepens, Bert; Saelens, Xavier; McLellan, Jason S.

Cell; 181(6): 1436-1441, 2020 Jun 11.

Artículo en Inglés | MEDLINE | ID: covidwho-598186

4.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Wrapp, Daniel; De Vlieger, Dorien; Corbett, Kizzmekia S; Torres, Gretel M; Wang, Nianshuang; Van Breedam, Wander; Roose, Kenny; van Schie, Loes; Hoffmann, Markus; Pöhlmann, Stefan; Graham, Barney S; Callewaert, Nico; Schepens, Bert; Saelens, Xavier; McLellan, Jason S.

Cell; 181(6): 1436-1441, 2020 Jun 11.

Artículo en Inglés | MEDLINE | ID: mdl-32531248

5.

Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.

Goodwin, Eileen; Gilman, Morgan S A; Wrapp, Daniel; Chen, Man; Ngwuta, Joan O; Moin, Syed M; Bai, Patricia; Sivasubramanian, Arvind; Connor, Ruth I; Wright, Peter F; Graham, Barney S; McLellan, Jason S; Walker, Laura M.

Immunity; 48(2): 339-349.e5, 2018 02 20.

Artículo en Inglés | MEDLINE | ID: mdl-29396163

6.

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

Corbett, Kizzmekia S; Edwards, Darin K; Leist, Sarah R; Abiona, Olubukola M; Boyoglu-Barnum, Seyhan; Gillespie, Rebecca A; Himansu, Sunny; Schäfer, Alexandra; Ziwawo, Cynthia T; DiPiazza, Anthony T; Dinnon, Kenneth H; Elbashir, Sayda M; Shaw, Christine A; Woods, Angela; Fritch, Ethan J; Martinez, David R; Bock, Kevin W; Minai, Mahnaz; Nagata, Bianca M; Hutchinson, Geoffrey B; Wu, Kai; Henry, Carole; Bahl, Kapil; Garcia-Dominguez, Dario; Ma, LingZhi; Renzi, Isabella; Kong, Wing-Pui; Schmidt, Stephen D; Wang, Lingshu; Zhang, Yi; Phung, Emily; Chang, Lauren A; Loomis, Rebecca J; Altaras, Nedim Emil; Narayanan, Elisabeth; Metkar, Mihir; Presnyak, Vlad; Liu, Cuiping; Louder, Mark K; Shi, Wei; Leung, Kwanyee; Yang, Eun Sung; West, Ande; Gully, Kendra L; Stevens, Laura J; Wang, Nianshuang; Wrapp, Daniel; Doria-Rose, Nicole A; Stewart-Jones, Guillaume; Bennett, Hamilton.

Nature; 586(7830): 567-571, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32756549

7.

Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.

Ye, Xiaohua; Su, Hang; Wrapp, Daniel; Freed, Daniel C; Li, Fengsheng; Yuan, Zihao; Tang, Aimin; Li, Leike; Ku, Zhiqiang; Xiong, Wei; Jaijyan, Dabbu; Zhu, Hua; Wang, Dai; McLellan, Jason S; Zhang, Ningyan; Fu, Tong-Ming; An, Zhiqiang.

PLoS Pathog; 16(8): e1008736, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32745149

8.

The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation.

Wrapp, Daniel; McLellan, Jason S.

J Virol; 93(23)2019 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-31534041

9.

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.

Pallesen, Jesper; Wang, Nianshuang; Corbett, Kizzmekia S; Wrapp, Daniel; Kirchdoerfer, Robert N; Turner, Hannah L; Cottrell, Christopher A; Becker, Michelle M; Wang, Lingshu; Shi, Wei; Kong, Wing-Pui; Andres, Erica L; Kettenbach, Arminja N; Denison, Mark R; Chappell, James D; Graham, Barney S; Ward, Andrew B; McLellan, Jason S.

Proc Natl Acad Sci U S A; 114(35): E7348-E7357, 2017 08 29.

Artículo en Inglés | MEDLINE | ID: mdl-28807998

10.

General Assessment of Humoral Activity in Healthy Humans.

Stafford, Phillip; Wrapp, Daniel; Johnston, Stephen Albert.

Mol Cell Proteomics; 15(5): 1610-21, 2016 05.

Artículo en Inglés | MEDLINE | ID: mdl-26902205

11.

Site-specific glycan analysis of the SARS-CoV-2 spike.

Watanabe, Yasunori; Allen, Joel D; Wrapp, Daniel; McLellan, Jason S; Crispin, Max.

Science; 2020 May 04.

Artículo en Inglés | MEDLINE | ID: covidwho-187772

12.

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

Wrapp, Daniel; Wang, Nianshuang; Corbett, Kizzmekia S; Goldsmith, Jory A; Hsieh, Ching-Lin; Abiona, Olubukola; Graham, Barney S; McLellan, Jason S.

Science; 367(6483): 1260-1263, 2020 03 13.

Artículo en Inglés | MEDLINE | ID: covidwho-1461

13.

Broad neutralization of SARS-related viruses by human monoclonal antibodies.

Wec, Anna Z; Wrapp, Daniel; Herbert, Andrew S; Maurer, Daniel P; Haslwanter, Denise; Sakharkar, Mrunal; Jangra, Rohit K; Dieterle, M Eugenia; Lilov, Asparouh; Huang, Deli; Tse, Longping V; Johnson, Nicole V; Hsieh, Ching-Lin; Wang, Nianshuang; Nett, Juergen H; Champney, Elizabeth; Burnina, Irina; Brown, Michael; Lin, Shu; Sinclair, Melanie; Johnson, Carl; Pudi, Sarat; Bortz, Robert; Wirchnianski, Ariel S; Laudermilch, Ethan; Florez, Catalina; Fels, J Maximilian; O'Brien, Cecilia M; Graham, Barney S; Nemazee, David; Burton, Dennis R; Baric, Ralph S; Voss, James E; Chandran, Kartik; Dye, John M; McLellan, Jason S; Walker, Laura M.

Science; 2020 Jun 15.

Artículo en Inglés | MEDLINE | ID: covidwho-599033

14.

Immunogenicity of a DNA vaccine candidate for COVID-19.

Smith, Trevor R F; Patel, Ami; Ramos, Stephanie; Elwood, Dustin; Zhu, Xizhou; Yan, Jian; Gary, Ebony N; Walker, Susanne N; Schultheis, Katherine; Purwar, Mansi; Xu, Ziyang; Walters, Jewell; Bhojnagarwala, Pratik; Yang, Maria; Chokkalingam, Neethu; Pezzoli, Patrick; Parzych, Elizabeth; Reuschel, Emma L; Doan, Arthur; Tursi, Nicholas; Vasquez, Miguel; Choi, Jihae; Tello-Ruiz, Edgar; Maricic, Igor; Bah, Mamadou A; Wu, Yuanhan; Amante, Dinah; Park, Daniel H; Dia, Yaya; Ali, Ali Raza; Zaidi, Faraz I; Generotti, Alison; Kim, Kevin Y; Herring, Timothy A; Reeder, Sophia; Andrade, Viviane M; Buttigieg, Karen; Zhao, Gan; Wu, Jiun-Ming; Li, Dan; Bao, Linlin; Liu, Jiangning; Deng, Wei; Qin, Chuan; Brown, Ami Shah; Khoshnejad, Makan; Wang, Nianshuang; Chu, Jacqueline; Wrapp, Daniel; McLellan, Jason S.

Nat Commun; 11(1): 2601, 2020 05 20.

Artículo en Inglés | MEDLINE | ID: covidwho-326048

15.

Site-specific glycan analysis of the SARS-CoV-2 spike.

Watanabe, Yasunori; Allen, Joel D; Wrapp, Daniel; McLellan, Jason S; Crispin, Max.

Science; 369(6501): 330-333, 2020 07 17.

Artículo en Inglés | MEDLINE | ID: mdl-32366695

16.

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

Wrapp, Daniel; Wang, Nianshuang; Corbett, Kizzmekia S; Goldsmith, Jory A; Hsieh, Ching-Lin; Abiona, Olubukola; Graham, Barney S; McLellan, Jason S.

Science; 367(6483): 1260-1263, 2020 03 13.

Artículo en Inglés | MEDLINE | ID: mdl-32075877

17.

Structural basis for assembly of non-canonical small subunits into type I-C Cascade.

O'Brien, Roisin E; Santos, Inês C; Wrapp, Daniel; Bravo, Jack P K; Schwartz, Evan A; Brodbelt, Jennifer S; Taylor, David W.

Nat Commun; 11(1): 5931, 2020 11 23.

Artículo en Inglés | MEDLINE | ID: mdl-33230133

18.

Iterative screen optimization maximizes the efficiency of macromolecular crystallization.

Jones, Harrison G; Wrapp, Daniel; Gilman, Morgan S A; Battles, Michael B; Wang, Nianshuang; Sacerdote, Sofia; Chuang, Gwo Yu; Kwong, Peter D; McLellan, Jason S.

Acta Crystallogr F Struct Biol Commun; 75(Pt 2): 123-131, 2019 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-30713164

19.

Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection.

Goodwin, Matthew L; Webster, Helen S; Wang, Hsuan-Yuan; Jenks, Jennifer A; Nelson, Cody S; Tu, Joshua J; Mangold, Jesse F; Valencia, Sarah; Pollara, Justin; Edwards, Whitney; McLellan, Jason S; Wrapp, Daniel; Fu, Tong-Ming; Zhang, Ningyan; Freed, Daniel C; Wang, Dai; An, Zhiqiang; Permar, Sallie R.

Virology; 548: 182-191, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32838941

20.

Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures.

Melero, Roberto; Sorzano, Carlos Oscar S; Foster, Brent; Vilas, José-Luis; Martínez, Marta; Marabini, Roberto; Ramírez-Aportela, Erney; Sanchez-Garcia, Ruben; Herreros, David; Del Caño, Laura; Losana, Patricia; Fonseca-Reyna, Yunior C; Conesa, Pablo; Wrapp, Daniel; Chacon, Pablo; McLellan, Jason S; Tagare, Hemant D; Carazo, Jose-Maria.

IUCrJ; 7(Pt 6)2020 Sep 29.

Artículo en Inglés | MEDLINE | ID: mdl-33063791

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Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.

The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation.

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.

General Assessment of Humoral Activity in Healthy Humans.

Site-specific glycan analysis of the SARS-CoV-2 spike.

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

Broad neutralization of SARS-related viruses by human monoclonal antibodies.

Immunogenicity of a DNA vaccine candidate for COVID-19.

Site-specific glycan analysis of the SARS-CoV-2 spike.

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

Structural basis for assembly of non-canonical small subunits into type I-C Cascade.

Iterative screen optimization maximizes the efficiency of macromolecular crystallization.

Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection.

Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures.