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INTRODUCTION: Diarrheal diseases constitute a significant public health problem in terms of mortality and morbidity. In Honduras and around the world, RVs have consistently emerged as the single most important etiologic agent in acute childhood diarrhea. However, other viruses, such as NoVs and HAstVs, have also been shown to be responsible for viral gastroenteritis. Unfortunately, the country has limited information concerning the etiologic role of these viral agents in acute gastroenteritis. This study investigated the frequency, genotypes, and epidemiological characteristics of RV-A, NoVs, and HAstVs among children under 5 years old in Distrito Central, Honduras. METHODS: Stool samples and their corresponding epidemiological data were collected from children with acute gastroenteritis in three healthcare centers in Distrito Central. All samples were screened by immunoassays for RV-A and HAstVs. RV-A-positive samples were molecularly characterized by RT-PCR and genotyping assays. RT-PCR was also applied to confirm HAstVs positivity and to detect NoVs, followed by nucleotide sequencing to assign their genotypes. RESULTS: Our results show that at least one viral agent was detected in 31% of the children. The frequency of RV-A, NoVs, and HAstVs was 14%, 13%, and 5%, respectively. The most frequent RV-A genotype was G2P[4], occurring in 93% of cases. 92.3% of NoVs-positive samples belonged to genogroup II, with GII.4 and GII.16 being the most common. HAstVs were clustered into three genotypes: HAstV-1, HAstV-2, and HAstV-8. Only one sample showed coinfection with NoVs and HAstVs. CONCLUSION: This comprehensive molecular and epidemiological characterization of enteric viruses demonstrates the vast diversity of these agents and describes for the first time NoVs and HAstVs as causative agents of acute childhood gastroenteritis in Distrito Central, Honduras. This suggests that further in-depth studies of the pediatric population are necessary to develop and implement effective preventive and control measures in the country.
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Heces , Gastroenteritis , Genotipo , Humanos , Honduras/epidemiología , Gastroenteritis/virología , Gastroenteritis/epidemiología , Preescolar , Lactante , Heces/virología , Masculino , Femenino , Diarrea/virología , Diarrea/epidemiología , Filogenia , Rotavirus/genética , Rotavirus/aislamiento & purificación , Rotavirus/clasificación , ARN Viral/genética , Norovirus/genética , Norovirus/clasificación , Norovirus/aislamiento & purificación , Infecciones por Caliciviridae/epidemiología , Infecciones por Caliciviridae/virología , Enfermedad Aguda/epidemiología , Recién Nacido , Infecciones por Enterovirus/virología , Infecciones por Enterovirus/epidemiologíaRESUMEN
Objective: Identify and analyze the role of nursing professionals in the development and care of adolescent health in Honduras, by analyzing the curricular content of the training provided to nursing students with respect to adolescent health, and by studying policies on adolescent health. Methods: Mixed methods study, with a sequential explanatory approach, carried out from May to July 2023 through surveys of nursing schools, analysis of policy documents, a survey with nursing professionals, and a focus group. Quantitative data were analyzed using descriptive statistics and qualitative data, applying the theoretical framework of Walt and Gilson. Results: During the research, 18 documents were analyzed and seven nursing schools, 141 nurses, and 10 key actors in leadership positions participated. The results point to the need to update and disseminate the regulatory framework, ensure the necessary resources and structure to implement sustainable intersectoral programs, and train professionals. Schools are an important space for the implementation of actions; in this context, the adoption of school nursing programs could be beneficial. Nurses were identified as key figures in program implementation and should be taken into consideration when developing policies aimed at adolescents. Conclusions: Nurses participate in various stages of the policy implementation process and can make important contributions to school health at the first level of care. To this end, it is necessary to increase the capacities of nurses and nursing educators in relation to current and relevant issues in adolescent care.
Objetivo: Identificar e analisar o papel dos profissionais de enfermagem no desenvolvimento e na atenção à saúde de adolescentes em Honduras por meio de análise do conteúdo da formação dos estudantes de enfermagem em saúde de adolescentes e das políticas relacionadas aos adolescentes. Métodos: Estudo de métodos mistos, com abordagem sequencial explanatória, realizado de maio a julho de 2023 por meio de um questionário aplicado a escolas de enfermagem, análise de documentos de política, um questionário aplicado a profissionais de enfermagem e um grupo focal. Os dados quantitativos foram analisados mediante estatísticas descritivas, e os qualitativos, usando o modelo teórico de Walt e Gilson. Resultados: Durante a pesquisa, foram analisados 18 documentos. Sete escolas de enfermagem, 141 profissionais de enfermagem e 10 atores-chave em cargos de liderança participaram do estudo. Os resultados apontam para a necessidade de atualizar e divulgar o marco normativo, garantir recursos e estrutura para a implementação de programas intersetoriais e sustentáveis e capacitar os profissionais. A escola representa um espaço importante para a implementação de ações, contexto no qual a adoção da enfermagem escolar pode ser proveitosa. Os profissionais de enfermagem foram identificados como atores-chave na implementação dos programas e devem ser levados em consideração no desenvolvimento de políticas voltadas para esse público. Conclusões: Os profissionais de enfermagem estão envolvidos em vários estágios do processo de implementação de políticas e podem fazer aportes importantes para a saúde escolar no nível da atenção primária. Para isso, é necessário aumentar a capacitação dos profissionais e docentes de enfermagem em tópicos atuais e relevantes da atenção a adolescentes.
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Kodamaea ohmeri is an environmental yeast considered a rare emerging pathogen. In clinical settings, the correct identification of this yeast is relevant because some isolates are associated with resistance to antifungals. There is a lack of available data regarding the geographical distribution, virulence, and drug resistance profile of K. ohmeri. To contribute to the knowledge of this yeast, this study aimed to describe in depth three isolates of K. ohmeri associated with fungemia in Honduras. The identification of the isolates was carried out by sequencing the ribosomal ITS region. In addition, the susceptibility profile to antifungals was determined, and some properties associated with virulence were evaluated (exoenzyme production, biofilm formation, cell adhesion, and invasion). The isolates showed strong protease, phospholipase, and hemolysin activity, in addition to being biofilm producers. Adherence and invasion capacity were evident in the HeLa and Raw 264.7 cell lines, respectively. This study expands the understanding of the underlying biological traits associated with virulence in K. ohmeri, and it is the first report of the detection and identification of K. ohmeri in Honduras as a cause of human infection.
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Objective: To map ophthalmologist locations and surgical practices as they vary sub-nationally within Honduras to maximize the impact of efforts to develop cataract surgical capacity. Methods: An anonymous survey was sent to all Honduran ophthalmologists with questions on surgical volume, department-level location, type of facility in which they work, surgical methods, and age. Surgical volume, population, and poverty data sourced through the Oxford Poverty Human Development Initiative were mapped at the department level, and cataract surgical rates (CSR; surgeries per million population per year) were calculated and mapped. Results: Sixty-one of the 102 Honduran ophthalmologists contacted responded. Of those, 85% perform cataract surgery, and 49% work at least part time in a non-profit or governmental facility. Honduras has fewer surgical ophthalmologists per million than the global average, and though national CSR appears to be increasing, it varies significantly between departments. The correlation between CSR and poverty is complex, and outliers provide valuable insights. Conclusion: Mapping ophthalmological surgical practices as they relate to population and poverty at a sub-national level provides important insights into geographic trends in the need for and access to eye care. Such insights can be used to guide efficient and effective development of cataract surgical capacity.
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Catarata , Oftalmología , Médicos , Humanos , Honduras/epidemiología , Catarata/epidemiología , Recursos HumanosRESUMEN
We have studied the allele frequencies for 23 STR autosomal loci (CSF1PO, FGA, TH01, vWA, D1S1656, D2S1338, D2S441, D3S1358, D5S818, D7S820, D8S1179, D10S1248, D12S391, D13S317, D16S539, D18S51, D19S433, D21S11; with the purpose to increase the power of discrimination, the markers Penta D, Penta E, D22S1045, TPOX and SE33 were included), from a sample of 100 unrelated individuals of Lenca ethnic group in Honduras, Central America.
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Purpose: The pathways by which adverse childhood experiences (ACEs) are associated with early marriage and early pregnancy are poorly understood. Early marriage and early pregnancy may be risk factors for adulthood intimate partner violence (IPV). The aim of this study was to assess the relationships among ACEs, early marriage, early pregnancy, and IPV among women in Honduras. Method: We used weighted data from 1,436 women aged 18-24 years from the nationally representative 2017 Honduras Violence Against Children and Youth Survey. We used path analysis to estimate relationships and accounted for sample design, non-response, and within-country clustering. Results: We found that ACEs had differential relationships with outcomes of interest. For example, witnessing violence in the community was directly associated with increased probability of early pregnancy (10 percentage points (PP); 95% CI: 0.04, 0.15) and IPV (6 PP; 95% CI: 0.01, 0.10), while emotional violence was not directly or indirectly associated with any outcome. Early marriage and early pregnancy had no direct or indirect effect on IPV, but the total effect of early marriage on IPV was significant. Conclusions: Understanding the relationship between ACEs, early marriage, early pregnancy, and IPV may help inform prevention efforts. For example, programs aiming to reduce early pregnancy may consider addressing sexual violence experienced in childhood.
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Background: Atopic dermatitis (AD) is an inflammatory skin condition, often multifactorial in origin, and most commonly manifests during childhood. Although there remains a deficit in literature, current data suggest Honduras may have the highest prevalence and severity of AD among all Latin American countries. Objective: To assess the current prevalence of pediatric AD in Honduras and evaluate existing gaps in available literature to monitor disease burden. Methods: A comprehensive literature search was performed in March 2023. Articles were removed if they were published before 2007, were of the incorrect study design, or were focused on countries outside of Honduras. The articles were independently reviewed by 2 authors. Results: The initial literature search yielded 174 studies, of which 7 met inclusion criteria. AD prevalence rates in children in Honduras ranged from 0.7% to 40.0%. Limitations: Limitations include elements of study design, analytic methods, study populations, and limited articles. Conclusion: There appears to be a disproportionately higher prevalence and disease burden of pediatric AD in Honduras. Future research should acquire accurate data to further understand the prevalence, incidence, and severity of AD in Honduras.
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BACKGROUND: Efforts on a global scale for combating malaria have achieved substantial progress over the past twenty years. Two Central American nations have accomplished their goal of eliminating malaria: El Salvador and Belize. Honduras has decreased the incidence of malaria and now reports fewer than 4000 malaria cases annually, aspiring to reach elimination by 2030. To accomplish this goal, it is essential to assess the existing strategies employed for malaria control and to address the task of incorporating novel intervention strategies to identify asymptomatic reservoirs. METHODS: A survey for detecting asymptomatic cases was carried out in the community of Kaukira, in Gracias a Dios, Honduras, focusing on malaria transmission during 2023. Asymptomatic community members were recruited as participants, malaria screening was performed through a rapid diagnostic test in situ, and a blood sample was collected on filter paper. Highly sensitive molecular assays based on photo-induced electron transfer PCR (PET-PCR) were performed to detect the two species of Plasmodium circulating in Honduras: Plasmodium vivax and Plasmodium falciparum. In addition, the identification of the parasite species was verified by amplifying three genetic markers (Pvmsp3α, Pvmsp3ß, and Pfmsp1). RESULTS: A total of 138 participants were recruited, mostly adult women. All individuals tested negative on the rapid diagnostic test. Positive results for malaria were detected by PET-PCR in 17 samples (12.3%). Most samples (12 out of 17) were amplified with a Ct value between 37 and 42, indicating very low parasitemias. Out of the 17 samples, 16 of them also showed amplification in the species assays. There were nine cases of P. falciparum infections and seven cases of P. vivax infections that were further confirmed by nested PCR (nPCR) of Pvmsp3 and Pfmsp1. Parasitemias ranged from 100 p/µL to less than 0.25 p/µL. One sample showed mixed infection. CONCLUSIONS: The existence of asymptomatic malaria reservoirs in Honduras can contribute to disease transmission and pose a challenge that may hinder elimination efforts, requiring public health authorities to modify surveillance strategies to identify the disease and treat this population accordingly.
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INTRODUCTION: The frequency of detected strongyloidiasis is affected by the selected laboratory method in the studied population. Considering that Honduras has few community-based studies, the analysis of the laboratory record data can provide information helping to understand this parasitosis. OBJECTIVE: To estimate the frequency and to identify the factors associated with strongyloidiasis, analyzing the laboratory records of the Servicio de Parasitología at Hospital Escuela in Tegucigalpa (Honduras) between 2010 and 2022. MATERIALS AND METHODS: We carried out a descriptive, cross-sectional, analytical study. The laboratory diagnosis consisted of stool samples' examination by direct smear and modified Baermann technique. We estimated frequencies and percentages. The statistical association was calculated with prevalence ratios and a 95% confidence interval. Software R, version 4.2.0, and epiR package, version 2.0.46, were used to perform the analysis. RESULTS: The frequency of strongyloidiasis was 0.29% (112/38,085). It was higher with the modified Baermann technique (0.87%; 40/4,575) among male patients (0.44%; 70/15,758). Regarding the age, strongyloidiasis was higher in the 20-40 years old group (0.41%; 28/6,886) with direct smear and 41-61 years old (1.14%; 14/1,232) group with the modified Baermann technique. Among the factors associated with strongyloidiasis were age between 20 and 61 years old (PR=2.26, CI 95%=1.53-3.31), male patients (PR=2.34, CI 95%=1.603.44), mucus (PR=1.86, CI 95%=1.22-2.83) and Charcot-Leyden crystals in stool (PR=8.47, CI 95%=5.14-13.96); watery stool (PR=2.39, CI 95%=1.55-3.68), and other helminthiases (PR=6.73, CI 95%=3.98-11.38). Associated factors to cases detected with the modified Baermann technique were outpatient consultation (PR=4.21, CI 95%=1.91-9.28) and formed stools (PR=3.99, CI 95%=1.94-8.19). CONCLUSIONS: The modified Baermann technique increased the detection of strongyloidiasis almost four times. Most cases were distributed among male adults. The cases diagnosed exclusively with the modified Baermann technique have differences from those with observed larvae in the direct smear. It is necessary to develop community-based population studies.
Introducción: La detección de estrongiloidiasis depende del método de diagnóstico utilizado y la población estudiada. Dado que en Honduras hay pocos estudios poblacionales, el análisis de los datos de laboratorio puede generar información que ayude a entender esta parasitosis. Objetivo: Estimar la frecuencia e identificar los factores asociados a la estrongiloidiasis mediante el análisis de los registros de laboratorio del Servicio de Parasitología del Hospital Escuela en Tegucigalpa (Honduras) durante el periodo 2010-2022. Materiales y métodos: Se llevó a cabo un estudio descriptivo, transversal y analítico. El diagnóstico de laboratorio consistió en el análisis de muestras de heces con los métodos directo y Baermann modificado. Se estimaron frecuencias y porcentajes, y la asociación estadística se calculó con razón de prevalencia e intervalos de confianza del 95 %. Se utilizaron los programas R, versión 4.2.0, y el paquete epiR, versión 2.0.46, para ejecutar los análisis estadísticos. Resultados: La frecuencia general de estrongiloidiasis fue 0,29 % (112/38.085). Dicha frecuencia de detección fue mayor con el método de Baermann modificado (0,87 %; 40/4.575), entre pacientes masculinos (0,44 %; 70/15.758). También fue mayor en el rango de edad 20-40 años (0,41%; 28/6.886) por examen directo y entre los 41-61 años (1,14%; 14/1.232) con el método de Baermann modificado. Entre los factores asociados con la estrongiloidiasis se encontraron: edad entre los 20 y los 61 años (RP=2,26; IC 95%=1,53-3,31), sexo masculino (RP=2,34; IC 95% =1,60-3.44), moco (RP=1,86; IC 95%=1,22-2,83) y cristales de Charcot-Leyden en heces (RP=8,47, IC 95%=5,14-13,96), heces líquidas (RP=2,39, IC 95%=1,55-3,68) y otras helmintiasis (RP=6,73, IC 95%=3,98-11,38). Como factores asociados a los casos detectados con el método de Baermann modificado están consulta externa (RP=4,21, IC 95%=1,91-9,28) y heces formadas (RP=3,99, IC 95%=1,94-8,19). Conclusiones: El método de Baermann modificado aumentó la frecuencia de detección de estrongiloidiasis casi cuatro veces. La mayoría de los casos se distribuyeron entre pacientes masculinos adultos. Los casos diagnosticados exclusivamente con el método de Baermann modificado tuvieron diferencias con los casos diagnosticados por examen directo. Es necesario realizar estudios poblacionales.
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Estrongiloidiasis , Adulto , Humanos , Masculino , Adulto Joven , Persona de Mediana Edad , Estrongiloidiasis/diagnóstico , Estrongiloidiasis/epidemiología , Centros de Atención Terciaria , Honduras/epidemiología , Estudios Transversales , LaboratoriosRESUMEN
RESUMEN Objetivo. Identificar y analizar el papel de los profesionales de enfermería en el desarrollo y la atención de la salud adolescente en Honduras, por medio del análisis de los contenidos de la formación de los estudiantes de enfermería y de las políticas relacionadas con la salud de los adolescentes. Métodos. Estudio de métodos mixtos, con enfoque explicativo secuencial, desarrollado de mayo a julio del 2023 por medio de encuesta con escuelas de enfermería, análisis de los documentos políticos, encuesta con profesionales de enfermería y grupo focal. Datos cuantitativos analizados mediante estadística descriptiva y datos cualitativos analizados mediante el marco teórico de Walt y Gilson. Resultados. Durante la investigación, se analizaron 18 documentos y participaron siete escuelas de enfermería, 141 enfermeras y 10 actores clave en posición de liderazgo. Los resultados apuntan a la necesidad de actualizar y difundir el marco normativo, garantizar recursos y estructura para implementar programas intersectoriales y sostenibles, y capacitar a los profesionales. La escuela representa un espacio importante para la implementación de acciones, contexto en el que la adopción de la enfermera escolar puede ser provechosa. Las enfermeras fueron identificadas como protagonistas en la aplicación de los programas y deben ser consideradas en el desarrollo de políticas dirigidas a este público. Conclusiones. Las enfermeras participan en diversas etapas del proceso de implementación de políticas y pueden hacer importantes contribuciones a la salud escolar en el primer nivel de salud. Para ello, es necesario aumentar la capacidad de las enfermeras y docentes de enfermería en temas actuales y relevantes en la atención a los adolescentes.
ABSTRACT Objective. Identify and analyze the role of nursing professionals in the development and care of adolescent health in Honduras, by analyzing the curricular content of the training provided to nursing students with respect to adolescent health, and by studying policies on adolescent health. Methods. Mixed methods study, with a sequential explanatory approach, carried out from May to July 2023 through surveys of nursing schools, analysis of policy documents, a survey with nursing professionals, and a focus group. Quantitative data were analyzed using descriptive statistics and qualitative data, applying the theoretical framework of Walt and Gilson. Results. During the research, 18 documents were analyzed and seven nursing schools, 141 nurses, and 10 key actors in leadership positions participated. The results point to the need to update and disseminate the regulatory framework, ensure the necessary resources and structure to implement sustainable intersectoral programs, and train professionals. Schools are an important space for the implementation of actions; in this context, the adoption of school nursing programs could be beneficial. Nurses were identified as key figures in program implementation and should be taken into consideration when developing policies aimed at adolescents. Conclusions. Nurses participate in various stages of the policy implementation process and can make important contributions to school health at the first level of care. To this end, it is necessary to increase the capacities of nurses and nursing educators in relation to current and relevant issues in adolescent care.
RESUMO Objetivo. Identificar e analisar o papel dos profissionais de enfermagem no desenvolvimento e na atenção à saúde de adolescentes em Honduras por meio de análise do conteúdo da formação dos estudantes de enfermagem em saúde de adolescentes e das políticas relacionadas aos adolescentes. Métodos. Estudo de métodos mistos, com abordagem sequencial explanatória, realizado de maio a julho de 2023 por meio de um questionário aplicado a escolas de enfermagem, análise de documentos de política, um questionário aplicado a profissionais de enfermagem e um grupo focal. Os dados quantitativos foram analisados mediante estatísticas descritivas, e os qualitativos, usando o modelo teórico de Walt e Gilson. Resultados. Durante a pesquisa, foram analisados 18 documentos. Sete escolas de enfermagem, 141 profissionais de enfermagem e 10 atores-chave em cargos de liderança participaram do estudo. Os resultados apontam para a necessidade de atualizar e divulgar o marco normativo, garantir recursos e estrutura para a implementação de programas intersetoriais e sustentáveis e capacitar os profissionais. A escola representa um espaço importante para a implementação de ações, contexto no qual a adoção da enfermagem escolar pode ser proveitosa. Os profissionais de enfermagem foram identificados como atores-chave na implementação dos programas e devem ser levados em consideração no desenvolvimento de políticas voltadas para esse público. Conclusões. Os profissionais de enfermagem estão envolvidos em vários estágios do processo de implementação de políticas e podem fazer aportes importantes para a saúde escolar no nível da atenção primária. Para isso, é necessário aumentar a capacitação dos profissionais e docentes de enfermagem em tópicos atuais e relevantes da atenção a adolescentes.
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Hondurans have been targeted for deportation since the 1980s, but today their deportations have grown disproportionate to their immigrant population size. They are more likely to face deportation than other targeted groups, such as Mexicans, Salvadorans and Guatemalans. Given Hondurans' singular position in the deportation system and the dearth of research about this group, we ask: What are the potential short- and long-term consequences of deportation for Honduran migrants, their families, and the broader community? To address this question, we utilize qualitative interviews with deportees, their families, and community members collected in Honduras in 2011 and 2014 as part of a multi-country research project our team conducted on the social impacts of deportations. While our findings in Honduras parallel those in other studies, we capture economic, social, and emotional effects beyond the individual deportees, including non-migrant family members and the broader community that receives them. Our longitudinal approach allows us to capture re-migration patterns as well.
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Introduction. The frequency of detected strongyloidiasis is affected by the selected laboratory method in the studied population. Considering that Honduras has few community-based studies, the analysis of the laboratory record data can provide information helping to understand this parasitosis. Objective. To estimate the frequency and to identify the factors associated with strongyloidiasis, analyzing the laboratory records of the Servicio de Parasitología at Hospital Escuela in Tegucigalpa (Honduras) between 2010 and 2022. Materials and methods. We carried out a descriptive, cross-sectional, analytical study. The laboratory diagnosis consisted of stool samples' examination by direct smear and modified Baermann technique. We estimated frequencies and percentages. The statistical association was calculated with prevalence ratios and a 95% confidence interval. Software R, version 4.2.0, and epiR package, version 2.0.46, were used to perform the analysis. Results. The frequency of strongyloidiasis was 0.29% (112/38,085). It was higher with the modified Baermann technique (0.87%; 40/4,575) among male patients (0.44%; 70/15,758). Regarding the age, strongyloidiasis was higher in the 20-40 years old group (0.41%; 28/6,886) with direct smear and 41-61 years old (1.14%; 14/1,232) group with the modified Baermann technique. Among the factors associated with strongyloidiasis were age between 20 and 61 years old (PR=2.26, CI 95%=1.53-3.31), male patients (PR=2.34, CI 95%=1.60-3.44), mucus (PR=1.86, CI 95%=1.22-2.83) and Charcot-Leyden crystals in stool (PR=8.47, CI 95%=5.14-13.96); watery stool (PR=2.39, CI 95%=1.55-3.68), and other helminthiases (PR=6.73, CI 95%=3.98-11.38). Associated factors to cases detected with the modified Baermann technique were outpatient consultation (PR=4.21, CI 95%=1.91-9.28) and formed stools (PR=3.99, CI95% =1.94-8.19). Conclusions. The modified Baermann technique increased the detection of strongyloidiasis almost four times. Most cases were distributed among male adults. The cases diagnosed exclusively with the modified Baermann technique have differences from those with observed larvae in the direct smear. It is necessary to develop community-based population studies.
Introducción. La detección de estrongiloidiasis depende del método de diagnóstico utilizado y la población estudiada. Dado que en Honduras hay pocos estudios poblacionales, el análisis de los datos de laboratorio puede generar información que ayude a entender esta parasitosis. Objetivo. Estimar la frecuencia e identificar los factores asociados a la estrongiloidiasis mediante el análisis de los registros de laboratorio del Servicio de Parasitología del Hospital Escuela en Tegucigalpa (Honduras) durante el periodo 2010-2022. Materiales y métodos. Se llevó a cabo un estudio descriptivo, transversal y analítico. El diagnóstico de laboratorio consistió en el análisis de muestras de heces con los métodos directo y Baermann modificado. Se estimaron frecuencias y porcentajes, y la asociación estadística se calculó con razón de prevalencia e intervalos de confianza del 95 %. Se utilizaron los programas R, versión 4.2.0, y el paquete epiR, versión 2.0.46, para ejecutar los análisis estadísticos. Resultados. La frecuencia general de estrongiloidiasis fue 0,29 % (112/38.085). Dicha frecuencia de detección fue mayor con el método de Baermann modificado (0,87 %; 40/4.575), entre pacientes masculinos (0,44 %; 70/15.758). También fue mayor en el rango de edad 20-40 años (0,41%; 28/6.886) por examen directo y entre los 41-61 años (1,14%; 14/1.232) con el método de Baermann modificado. Entre los factores asociados con la estrongiloidiasis se encontraron: edad entre los 20 y los 61 años (RP=2,26; IC 95%=1,53-3,31), sexo masculino (RP=2,34; IC95%=1,60-3.44), moco (RP=1,86; IC 95%=1,22-2,83) y cristales de Charcot-Leyden en heces (RP=8,47, IC 95%=5,14-13,96), heces líquidas (RP=2,39, IC 95%=1,55-3,68) y otras helmintiasis (RP=6,73, IC 95%=3,98-11,38). Como factores asociados a los casos detectados con el método de Baermann modificado están consulta externa (RP=4,21, IC 95%=1,91-9,28) y heces formadas (RP=3,99, IC 95%=1,94-8,19). Conclusiones. El método de Baermann modificado aumentó la frecuencia de detección de estrongiloidiasis casi cuatro veces. La mayoría de los casos se distribuyeron entre pacientes masculinos adultos. Los casos diagnosticados exclusivamente con el método de Baermann modificado tuvieron diferencias con los casos diagnosticados por examen directo. Es necesario realizar estudios poblacionales.
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Strongyloides stercoralis , Enfermedades Parasitarias , Estrongiloidiasis , Helmintiasis , HondurasRESUMEN
Antecedentes: El Instituto de Enfermedades Infecciosas y Parasitología Antonio Vidal conmemora el trigésimo aniversario de su creación (1993-2023). Objetivo: Realizar un análisis bibliométrico de la producción científica del Dr. Antonio Vidal Mayorga en la Revista Médica Hondureña (RMH). Métodos: Análisis bibliométrico y revisión de alcance mediante búsquedas digitales en la Biblioteca Virtual en Salud de Honduras (https:// honduras.bvsalud.org/) y la RMH (https://revistamedicahondurena. hn/), y archivos físicos del Instituto Antonio Vidal. Los artículos fueron clasificados por tipo, año de publicación, tema específico (enfermedades transmisibles, agentes etiológicos y vectoriales, enfermedades crónicas no transmisibles, otros) y tema general (especialidades médicas, enfermedades, reseñas biográficas, actividades asistenciales y de salud pública, otros). Resultados: En los primeros 18 años de la RMH (1930-1947), el Dr. Vidal publicó 79 artículos: caso clínico 19, opinión 18, original 17, revisiones bibliográficas 11, reseñas de revistas 7 y libros 2, editoriales 5. Los años con mayor número de publicaciones fueron 1934 (10) y 1945 (16). Los temas generales con el mayor número de publicaciones fueron malaria (22) y deficiencias nutricionales (9). Se destacan sus observaciones originales con caracterizaciones clínicas, resultados de laboratorio y observaciones epidemiológicas en el campo, incluyendo observaciones entomológicas, y los artículos de opinión con propuestas sobre la organización y administración de la salud pública del país. Discusión: El Dr. Antonio Vidal Mayorga, médico y maestro ejemplar, se distingue en el contexto de la época en que vivió. Su obra fue impulsada por su capacidad de conjuntar la clínica, la epidemiología, el laboratorio, la salud pública, la investigación, la docencia y la proyección social...(AU)
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Humanos , Bibliometría , Bibliometría , Publicación Periódica , Docentes MédicosRESUMEN
ABSTRACT Dogs are considered to be the main domestic reservoir associated with the transmission of Leishmania (L.) infantum chagasi to humans in endemic areas of visceral leishmaniasis in America. However, little is known about the role of canines as a source of infection in endemic areas of nonulcerated cutaneous leishmaniasis (NUCL). Therefore, the objective of the present study was to investigate the role of dogs as a possible reservoir of the parasite in Southern Honduras. Dogs (n = 107) living with individuals affected by NUCL were clinically examined and biological material was collected for parasitological and immunological diagnosis. Most animals showed a healthy appearance and a few presented slight weight loss (64%), alopecia (7%), onychogryphosis (5%) and skin lesions (1%). The overall seroprevalence of Leishmania infection based on the DDP ® quick test and/or in-house ELISA serological test was 41%. The presence of the parasite's DNA was confirmed in 94% of the dogs; however, the average parasite load in the buffy coat was low at 6.09 parasites/µL, ranging between 0.221 and 50.2. The skin of seropositive dogs examined by histopathology using paraffin sections stained by hematoxylin and immunohistochemistry did not show cutaneous lesions or parasite amastigotes. Based on the absence of parasites in the skin and the low parasite load detected in the buffy coat, it seems that the dog does not represent a good source of infection for the vector in the endemic area of NUCL transmission in Southern Honduras. Other domestic and/or wild animals should be investigated.
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Antecedentes: Cuando el nervio óptico presenta una superficie mayor a 2.5 mm2 , y sin patologías asociadas, se trata de un macrodisco, cuya excavación es proporcional al tamaño aumentado del mismo. Con base en la distribución bajo la curva de Gauss, se define como "macrodisco" cuando está por encima de 2 desviaciones estándar arriba de la media. Se espera que solo el 2.3% de la población exceda estos límites. Objetivo: Determinar el tamaño promedio del disco óptico y proporción de macrodisco en la población sin glaucoma ni patologías retinianas que acude a dos clínicas oftalmológicas del occidente de Honduras, en el periodo de julio 2021 hasta julio 2022. Métodos: Estudio retrospectivo descriptivo. Se midieron los parámetros morfométricos del disco óptico mediante Tomografía de Coherencia Óptica ZEISS Cirrus HD Model 4000. Se definió macrodisco como: área del disco óptico >2.5 mm 2 y área del disco más 2 o más desviaciones estándar arriba de la media. Resultados: La proporción de macrodisco fue de 31% tomando en cuenta la definición de área de disco >2.5 mm2 , y 3% considerando la definición con base a la distribución bajo la curva de Gauss (>3.17mm2 ). Se obtuvo un promedio de área de disco óptico de 2.28±0.45 mm 2 , ratio copa/disco (C/D) de 0.59±0.13, ratio C/D vertical de 0.56±0.13, área de anillo neuroretiniano de 1.37±0.22 mm 2 , espesor de Capa de Fibras Nerviosas Retinianas (CFNR) de 97.4±10.664µm. Discusión: El área de disco promedio obtenido es mayor que los caucásicos, similar a lo reportado en los hispánicos, y menor que afrodescendientes y asiáticos...(AU)
Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Disco Óptico , Anomalías del Ojo , Tomografía de Coherencia Óptica/métodosRESUMEN
Antecedentes: En 2023 se conmemora el trigésimo aniversario del Instituto de Enfermedades Infecciosas y Parasito- logía Antonio Vidal (IAV), Tegucigalpa, Honduras, una fundación privada sin fines de lucro. Objetivo: Analizar la producción científica en cuya autoría al menos uno de los autores cuenta con afiliación institucional IAV, periodo 1993-2023. Métodos: Estudio bibliométrico recopilando datos a través de la búsqueda en la Biblioteca Virtual en Salud de Honduras (http://www.bvs.hn/RMH/ html5) y bases de datos (Google académico, Scopus y Web of Science [(WOS]) que ofrecen perfiles de la actividad investigativa de autores e instituciones. Se creó base de datos Excel utilizando los campos: autores, títulos, afiliaciones institucionales nacionales e internacionales, colaboración en la autoría por país, formato de publicación (libro/artículo científico), tipo de artículo, revistas nacionales e internacionales, año de publicación y número de citaciones. Resultados: Se identificaron 55 publicaciones, 44.8% (22) en idioma inglés, 87.3% (48) publicadas entre 2014 y 2023; 89.1% (49) se publicó en revistas científicas, 7.3% (4) en formato tipo libro/manual y 3.6% (2) preprint. De 49 artículos publicados, 51.0% (26) recibió 575 citas según Google Académico, 63.0% (14) recibió 217 citas según Scopus y 66.0% (15) recibió 306 citas según WOS. Discusión: A tres décadas de su constitución, el IAV aumentó el número de miembros y la producción científica. Aproximadamente la mitad de los artículos se han publicado en revistas internacionales con algún índice de impacto gracias a la red de colaboración y alianzas estratégicas de diferentes grupos de investigación a nivel global...(AU)
Asunto(s)
Bibliometría , Indicadores de Producción CientíficaRESUMEN
Plaguicidas en Honduras: Desafíos en la regulación y abordaje científico. RESUMEN El uso y la exposición a plaguicidas en Honduras plantean desafíos ineludibles para la salud pública. Este artículo aborda los retos en la regulación y en el enfoque científico de los plaguicidas en Honduras. Se resalta la falta de programas de muestreo y análisis para detectar productos potencialmente peligrosos, así como el fácil acceso a plaguicidas de grado profesional en hogares urbanos y rurales, como preocupaciones importantes. Se identifican debilidades en aspectos clave de la regulación y el enfoque científico de los plaguicidas, incluyendo la falta de rigor en la evaluación de riesgos y pruebas científicas requeridas para su aprobación, así como limitaciones en la capacidad técnica y recursos humanos de las agencias responsables del registro. Se enfatiza la importancia de programas de capacitación efectivos para los vendedores locales de plaguicidas, así como la educación de la población en general sobre los riesgos de la exposición a los mismos. En este análisis crítico, se destaca la necesidad de mejorar la regulación y el enfoque científico de los plaguicidas en Honduras para proteger la salud pública y el medio ambiente...(AU)
Asunto(s)
Uso de Plaguicidas , Exposición a Plaguicidas , Salud Pública , Riesgo a la SaludRESUMEN
ABSTRACT Objective. To understand the sexual and reproductive health (SRH) experiences of migrant women and girls of reproductive age (15-49 years) from the Northern Triangle of Central America (El Salvador, Guatemala and Honduras) during their journey to the United States. Methods. A descriptive, qualitative research design included 39 in-depth interviews with migrant women and unaccompanied migrant girls from El Salvador, Guatemala and Honduras from January to June 2022. Participants were recruited using purposive sampling. Interviews were transcribed, coded and analyzed using thematic analysis. Results. Migrant women and girls lack information and resources to manage their SRH during migration. The SRH of those traveling with smugglers is compromised due to their limited access to menstrual pads, water and sanitation services; the risks of transactional sex and sexual violence; the high risk of sexually transmitted infections; the inability to report sexual violence; the lack of access to SRH and prenatal services; and limited knowledge about their sexual and reproductive rights. Conclusions. There is a significant need for improved interventions during the predeparture phase of migration to inform migrant women and girls about the SRH risks they may encounter and to provide information and resources to support their SRH throughout their journey. Special attention should be directed towards trying to reach girls and women who will travel with smugglers.
RESUMEN Objetivo. Conocer las experiencias relacionadas con la salud sexual y reproductiva (SSR) de mujeres y niñas migrantes en edad reproductiva (15-49 años) del Triángulo Norte de América Central (El Salvador, Guatemala y Honduras) durante su viaje hacia Estados Unidos. Métodos. Se llevó a cabo una investigación descriptiva y cualitativa que incluyó 39 entrevistas en profundidad a mujeres y niñas no acompañadas migrantes de El Salvador, Guatemala y Honduras, entre enero y junio de 2022. El reclutamiento de las participantes se llevó a cabo mediante un muestreo intencional. Las entrevistas fueron transcritas, codificadas y analizadas mediante análisis temático. Resultados. Las mujeres y niñas migrantes carecen de información y recursos para cuidar su SSR durante la migración. La SSR de las personas que viajan con traficantes de personas se ve afectada por un acceso limitado a toallas menstruales, agua y servicios sanitarios; los riesgos del sexo transaccional y la violencia sexual; el alto riesgo de infecciones de transmisión sexual; la imposibilidad de denunciar la violencia sexual; la falta de acceso a servicios de SSR y prenatales; y el conocimiento limitado sobre sus derechos sexuales y reproductivos. Conclusiones. Existe una necesidad significativa de mejorar las intervenciones durante la fase previa a la migración para informar a las mujeres y niñas migrantes sobre los riesgos relacionados con la SSR que pueden encontrar y proporcionar información y recursos para apoyar su SSR a lo largo de su viaje. Debe prestarse especial atención a intentar llegar a las niñas y mujeres que viajarán con traficantes de personas.
RESUMO Objetivo. Conhecer as experiências de saúde sexual e reprodutiva (SSR) de mulheres e meninas migrantes na idade reprodutiva (15-49 anos) do Triângulo Norte da América Central (El Salvador, Guatemala e Honduras) durante sua viagem aos Estados Unidos. Método. Foi realizada uma pesquisa descritiva e qualitativa que incluiu 39 entrevistas em profundidade com mulheres e meninas não acompanhadas migrantes de El Salvador, Guatemala e Honduras, entre janeiro e junho de 2022. As entrevistas foram transcritas, codificadas e analisadas mediante análise temática. Resultados. As mulheres e meninas migrantes carecem de informações e recursos para cuidar seu SSR durante a migração. La SSR das pessoas que viajam com traficantes de pessoas é afetada pelo acesso limitado a absorventes menstruais, água e serviços sanitários; os riscos de sexo transacional e violência sexual; o alto risco de infecções de transmissão sexual; a impossibilidade de denunciar a violência sexual; a falta de acesso a serviços de SSR e pré-natais; e o conhecimento limitado sobre seus direitos sexuais e reprodutivos. Conclusões. Há uma necessidade significativa de melhorar as intervenções durante a fase anterior à migração para informar as mulheres e meninas migrantes sobre os riscos de SSR que podem encontrar e fornecer informações e recursos para apoiar seu SSR ao longo de sua viagem. Deve ser dada atenção especial para tentar chegar as meninas e mulheres que viajarão com traficantes de pessoas.
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Justificación: La muerte súbita constituye un problema de salud pública a nivel global. Su presentación súbita e inesperada tiene implicaciones médico-legales por lo que su abordaje diagnóstico en el ámbito forense es de gran importancia.Objetivo: Analizar la muerte súbita y su abordaje diagnóstico en la Dirección de Medicina Forense de Honduras. Metodología: Estudio descriptivo, retrospectivo de autopsias por muerte súbita en población de 10 a 55 años, realizadas en la sede de Tegucigalpa durante un período de cinco años (2015-2019). Los cálculos estadísticos fueron realizados con el programa R. Resultados: Se analizaron 165 casos de muerte súbita, 56% fueron de origen no cardiovascular y 44% de origen cardiovascular, 67% varones, con una media de edad de 39 años, DS+/-9,75. Las causas más frecuentes de muerte súbita no cardiovascular fueron digestivas (36%), respiratorias (34%), eventos cerebrovasculares hemorrágicos (14%) y muerte súbita en epilepsia (9%). Entre las muertes súbitas cardiovasculares las causas más frecuentes fueron la enfermedad coronaria aterosclerótica (67%), miocarditis (12%) y la muerte arrítmica con corazón estructuralmente normal (10%). Desde el punto de vista toxicológico destaca en ambas la asociación con el consumo de etanol (19%). Conclusiones: La muerte súbita de origen no cardiovascular fue la más frecuente, resultado condicionado por las limitantes del estudio. El abordaje actual de los casos de muerte súbita presenta importantes limitaciones por lo que se recomienda fortalecerlo implementando mejoras en la investigación medicolegal de la escena de la muerte, de los antecedentes familiares y el uso adecuado de los estudios complementarios toxicológicos e histopatológicos...(AU)
Asunto(s)
Humanos , Masculino , Médicos Forenses , Muerte Súbita , Autopsia , Muerte Súbita CardíacaRESUMEN
Introducción: El modelo de gestión hospitalaria es el conjunto de políticas y procesos que permiten tomar decisiones asertivas. Durante la pandemia de COVID-19, los sistemas de salud a nivel global necesitaron reorganización para responder a las necesidades presentadas. Sin embargo, no se tiene registro de dicho proceso en Honduras. Objetivo: Explorar las experiencias de profesionales de Enfermería relacionadas con la gerencia de servicios del Hospital "Mario Catarino Rivas" durante la pandemia de COVID-19. Métodos: Se realizó un estudio fenomenológico interpretativo sobre las experiencias de profesionales de Enfermería relacionadas con la gerencia de servicios del Hospital "Mario Catarino Rivas", durante la pandemia de COVID-19. La colecta de datos fue mediante entrevistas semiestructuradas a 20 profesionales de Enfermería en cargos de jefatura, como resultado de un muestreo deliberado. Los datos se analizaron con el método temático, con agrupación de las narraciones, se siguieron los siete pasos de la perspectiva de Colaizzi. Resultados: Se hallaron tres temas, siete subtemas y 30 conceptos, se encontró la calidad total el modelo gerencial utilizado para dar respuestas a las dificultades presentadas durante la pandemia COVID-19. Dentro de los principales desafíos se encontró "falta de recursos humanos" para dar respuesta a la demanda de pacientes. Conclusiones: Durante la COVID-19, se evidencia el importante rol del profesional de Enfermería en cargos gerenciales para mitigar el impacto económico en el sistema de salud hondureño, y garantizar la calidad de vida de los pacientes. Es necesario la apertura de espacios con mayor responsabilidad, con respaldo legal que fortalezca la práctica avanzada(AU)
Introduction: A hospital management model is the set of policies and processes that allow assertive decision making. During the COVID-19 pandemic, health systems worldwide required reorganization to respond to the emerging needs. However, there is no record of such process in Honduras. Objective: To explore the experiences of nursing professionals concerning the management of services at Hospital Mario Catarino Rivas during the COVID-19 pandemic. Methods: An interpretative phenomenological study was conducted on the experiences of nursing professionals concerning the management of services at Hospital Mario Catarino Rivas during the COVID-19 pandemic. The data were collected using semistructured interviews with 20 nursing professionals in head positions, as a result of a deliberate sampling. The data were analyzed using the thematic method, with clustering of narratives and following the seven steps of Colaizzi's perspective. Results: Three themes, 7 subthemes and 30 concepts were found. In addition, the overall quality of the management model used to respond to the difficulties presented during the COVID-19 pandemic was found. Among the main challenges, "lack of human resources" to respond to patient demand was found. Conclusions: During COVID-19, the important role of the nursing professional in managerial positions to mitigate the economic impact on the Honduran health system and to guarantee the quality of life of patients is evident. It is necessary to open spaces with greater responsibility, with legal support to strengthen advanced practice(AU)