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1.
J Synchrotron Radiat ; 31(Pt 3): 478-484, 2024 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-38592970

RESUMEN

Maximizing the performance of crystal monochromators is a key aspect in the design of beamline optics for diffraction-limited synchrotron sources. Temperature and deformation of cryo-cooled crystals, illuminated by high-power beams of X-rays, can be estimated with a purely analytical model. The analysis is based on the thermal properties of cryo-cooled silicon crystals and the cooling geometry. Deformation amplitudes can be obtained, quickly and reliably. In this article the concept of threshold power conditions is introduced and defined analytically. The contribution of parameters such as liquid-nitrogen cooling efficiency, thermal contact conductance and interface contact area of the crystal with the cooling base is evaluated. The optimal crystal illumination and the base temperature are inferred, which help minimize the optics deformation. The model has been examined using finite-element analysis studies performed for several beamlines of the Diamond-II upgrade.

2.
J Synchrotron Radiat ; 29(Pt 2): 377-385, 2022 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-35254300

RESUMEN

Crystal monochromators are often the primary optics in hard X-ray synchrotron beamlines. Management of power load is central to their design. Strict requirements on stability and deformation are to be met, as new-generation synchrotron sources deliver brighter beams of X-rays. This article sets out to illustrate an overall picture of the deformation caused by heat load in a cryo-cooled Si crystal monochromator using first principles. A theoretical model has been developed to predict the temperature distribution and surface deformation by applying intrinsic properties of Si material and the cooling system parameters. The model explains the universal behaviour of crystal slope error versus absorbed power; it has been benchmarked against experimental data and used to interpret finite-element analysis of cryogenically cooled crystals.

3.
Comput Methods Programs Biomed ; 218: 106729, 2022 May.
Artículo en Inglés | MEDLINE | ID: mdl-35279603

RESUMEN

BACKGROUND AND OBJECTIVES: For neurological simulation, an accurate deformation model of brain tissue is of key importance for faithful visual feedback. Existing models, however, do not take into account intracranial pulsation, which degrades significantly the realism of visual feedback. METHODS: In this paper, a finite element model incorporating intracranial pressure is proposed for simulating brain tissue deformation with pulsation. An implicit Euler method is developed to calculate the deformation of brain tissue. A circuit model of intracranial pressure dynamics is established based on cerebral blood and cerebrospinal fluid circulations. The intracranial pulsation of pressure is introduced into the deformation model, so that the simulated brain tissues pulsate with a rhythm in accord with the changes of intracranial pressure, which resembles real-life neurosurgery. RESULTS AND CONCLUSIONS: The experimental implementation of the proposed deformation model and the calculation method shows that it provides realistic simulation of brain tissue pulsation and real-time performance is achieved on an ordinary computer for certain procedures of neurosurgery.


Asunto(s)
Neurocirugia , Encéfalo/diagnóstico por imagen , Encéfalo/cirugía , Simulación por Computador , Análisis de Elementos Finitos , Procedimientos Neuroquirúrgicos
4.
Artículo en Inglés | MEDLINE | ID: mdl-23582050

RESUMEN

In this review, we provide an overview of the simulation techniques employed for modelling the flow of red blood cells (RBCs) in blood plasma. The scope of this review omits the fluid modelling aspect while focusing on other key components in the RBC-plasma model such as (1) describing the RBC deformation with shell-based and spring-based RBC models, (2) constitutive models for RBC aggregation based on bridging theory and depletion theory and (3) additional strategies required for completing the RBC-plasma flow model. These include topics such as modelling fluid-structure interaction with the immersed boundary method and boundary integral method, and updating the variations in multiphase fluid property through the employment of index field methods. Lastly, we summarily discuss the current state and aims of RBC modelling and suggest some research directions for the further development of this field of modelling.


Asunto(s)
Simulación por Computador , Eritrocitos/fisiología , Hemorreología/fisiología , Análisis Numérico Asistido por Computador , Deformación Eritrocítica , Membrana Eritrocítica/fisiología , Eritrocitos/citología , Humanos , Modelos Biológicos
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