Comparison of two skin imaging analysis instruments: The VISIA® from Canfield vs the ANTERA 3D® CS from Miravex.

BACKGROUND: The skin imaging analysis instruments are widely used to record and measure the surface and subsurface skin conditions. The main aim of this study is to reveal the differences and correlations in measuring wrinkle, skin texture, coloration/evenness, vascular features, and pore between two commercially available instruments. METHODS: Twenty-eight subjects were enrolled in the study. A 2*2 cm cardboard was used to make sure the two instruments analyze the same area. Pictures were taken and analyzed by the VISIA® from Canfield and the ANTERA 3D® CS from Miravex, in sequence. RESULTS: The spot, ultraviolet spot, brown spot, red area, texture values measured with VISIA® were positively correlated with age, while the pore and wrinkle values showed no significance. The wrinkle, texture, melanin, hemoglobin, pore index, pore volume values measured with ANTERA 3D® had a significantly positive correlation with age. The spot, brown spot values from VISIA® were positively correlated with the melanin value from ANTERA 3D® . Texture value measured with the two instruments revealed positive linear correlation. Strong correlation was found between the red area value from VISIA® and the hemoglobin value from ANTERA 3D® . Ultraviolet spot from VISIA® showed no linear correlation with the melanin value from ANTERA 3D® . Neither of the wrinkle and pore measured with the two instruments showed linear correlation. CONCLUSIONS: ANTERA 3D® relies on multidirectional illumination obtained by LEDs of different wavelengths from different directions which make it advanced at the qualitative evaluation of various dermatologic conditions. Compared with VISIA® , ANTERA 3D® is more sensitive in the assessment of wrinkle and it may also be available to evaluate the aging-related enlarged pore.

Comparison of two kinds of skin imaging analysis software: VISIA® from Canfield and IPP® from Media Cybernetics.

BACKGROUND: Skin imaging analysis, acting as a supplement to noninvasive bioengineering devices, has been widely used in medical cosmetology and cosmetic product evaluation. The main aim of this study is to assess the differences and correlations in measuring skin spots, wrinkles, vascular features, porphyrin, and pore between two commercially available image analysis software. MATERIALS AND METHODS: Seventy healthy women were included in the study. Before taking pictures, the dermatologist evaluated subjects' skin conditions. Test sites included the forehead, cheek, and periorbital skin. A 2 × 2 cm cardboard was used to make a mark on the skin surface. Pictures were taken using VISIA® under three kinds light conditions and analyzed using VISIA® and IPP® respectively. RESULTS: (1) Skin pore, red area, ultraviolet spot, brown spot, porphyrin, and wrinkle measured with VISIA® were correlated with those measured with IPP® (P < .01). (2) Spot, wrinkle, fine line, brown spot, and red area analyzed with VISIA® were correlated with age on the forehead and periorbital skin (P < .05). L-value, Crow's feet, ultraviolet spot, brown spot, and red area analyzed with IPP® were correlated with age on the periorbital skin (P < .05). (3) L-value, spot, wrinkle, fine line, porphyrin, red area, and pore analyzed with VISIA® and IPP® showed correlations with the subjective evaluation scores (P < .05). CONCLUSIONS: VISIA® and IPP® showed acceptable correlation in measuring various skin conditions. VISIA® showed a high sensibility when measured on the forehead skin. IPP® is available as an alternative software program to evaluate skin features.

Riehl's Melanosis: A Multimodality, In Vivo, Real-Time Skin Imaging Study with Cellular Resolution Optical Coherence Tomography and Advanced Skin Diagnosis System in a Tertiary Medical Center.

BACKGROUND: Riehl's melanosis is a psychologically devastating hyperpigmentary disorder that typically occurs on the face and neck. The study of Riehl's melanosis is limited due to its rarity, variable morphology, and lack of noninvasive diagnostic tools. Recent advances in skin imaging analysis and diagnostic systems improve diagnostic accuracy and enable the noninvasive, real-time evaluation of pigmentary disease. A comprehensive study of Riehl's melanosis clinical morphology with multimodality and in vivo skin imaging systems has yet to be reported. OBJECTIVES: To investigate the clinical features and in vivo advanced skin imaging findings of Riehl's melanosis. METHODS: We retrospectively investigated the clinical characteristics, dermoscopic, and histopathological features of Riehl's melanosis. We further utilized multimodality skin imaging analysis systems, including a cellular resolution optical coherence tomography (OCT) and new skin diagnosis system, to investigate the features of Riehl's melanosis. In addition, we compared OCT findings with histopathological features and clinical assessment. RESULTS: We evaluated 30 patients with Riehl's melanosis at a tertiary medical center from 2010 to 2022. The average age was 47.7 ± 12.3 (mean ± SD) years, predominantly female patients (female: n = 23; male: n = 7). Cellular resolution OCT imaging from lesion skin shows increased melanocyte capping, disrupted basement membrane, telangiectatic blood vessels, and melanophages in the dermis. The advanced skin diagnosis system captured subclinical erythema of the skin, highlighting the inflammatory nature of the disease. The results correlated well with histopathological findings. LIMITATIONS: This is a single-center, cross-sectional study. CONCLUSIONS: We highlight the features of Riehl's melanosis through a novel cellular resolution OCT and photographic skin diagnosis system. A multimodality skin diagnosis system can serve as a real-time, in vivo, noninvasive method for evaluating pigmentary disorders.