Genotypes of clinical varicella-zoster virus isolates from Manaus, Brazil
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;52: e20180166, 2019. tab, graf
Article
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| LILACS
| ID: biblio-1041564
Biblioteca responsable:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Vaccination against varicella-zoster virus (VZV) has been effective and safe in countries that routinely administer the vaccine. Brazil began universal VZV vaccination in 2013. This study aimed to identify VZV genotypes present in Manaus, Brazil prior to widespread immunization.METHODS:
Vesicular lesions or cerebral-spinal-fluid samples were collected from patients diagnosed with VZV, herpes zoster, or meningitis/encephalitis. DNA was extracted, amplified, and sequenced.RESULTS:
Half the isolates were clade-5 viruses and the remaining were divided between the European clades 1 and 3.CONCLUSIONS:
This study provides insights into the circulating VZV genotypes in Manaus prior to widespread vaccination.Palabras clave
Texto completo:
1
Bases de datos:
LILACS
Asunto principal:
Herpesvirus Humano 3
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Infección por el Virus de la Varicela-Zóster
Límite:
Adolescent
/
Adult
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Aged
/
Child
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Child, preschool
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Female
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Humans
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Male
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
MEDICINA TROPICAL
Año:
2019
Tipo del documento:
Article
País de afiliación:
Brasil
/
Estados Unidos