Evidence for current circulation of an ancient West Nile virus strain (NY99) in Brazil
Siconelli, Márcio Junio Lima; Jorge, Daniel Macedo de Melo; Castro-Jorge, Luiza Antunes de; Fonseca-Júnior, Antônio Augusto; Nascimento, Mateus Laguardia; Floriano, Vitor Gonçalves; Souza, Fransérgio Rocha de; Queiroz-Júnior, Eudson Maia de; Camargos, Marcelo Fernandes; Costa, Eliana Dea Lara; Carvalho, Adolorata Aparecida Bianco; Fonseca, Benedito Antonio Lopes da.
Rev. Soc. Bras. Med. Trop;
54: e0687-2020, 2021. graf
Artículo
en Inglés
| LILACS | ID: biblio-1155578
Abstract
INTRODUCTION:
In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease.AIM:
We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state. Both infections occurred in 2019.METHODS:
WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq.RESULTS:
Phylogenetic analysis revealed that the isolate belongs to lineage 1a, clustering with the NY99 strain, a strain that has not circulated in the USA since 2005.CONCLUSIONS:
Our findings reinforce the hypothesis that WNV has been silently circulating in Brazil for many years.
Biblioteca responsable:
BR1.1
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