Evaluation of aversive behavior in Rattus norvegicus experimentally infected by two distinct strains of Toxoplasma gondii (ME49 and VEG): study of epigenetic markers
Rev. Soc. Bras. Med. Trop
; 55: e0122, 2022. graf
Article
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LILACS-Express
| LILACS
| ID: biblio-1407005
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BR1.1
ABSTRACT
ABSTRACT Background:
Behavioral changes in Rattus norvegicus infected with two strains of Toxoplasma gondii (ME49 and VEG) were investigated.Methods:
Rats were evaluated for motor activity and aversion or attraction to cat urine 60 days after infection. After euthanasia, arginine-vasopressin gene methylation in the central nervous system was evaluated.Results:
A significant difference was observed in the methylation of the arginine-vasopressin promoter gene between rats infected with the ME49 and VEG strains.Conclusions:
Although differences were not observed in many parameters, significant differences were observed in the methylation of the arginine-vasopressin promoter gene in rats infected with the two studied strains.
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Bases de datos:
LILACS
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
MEDICINA TROPICAL
Año:
2022
Tipo del documento:
Article
País de afiliación:
Brasil