Resultados a largo plazo del empleo de stents recubiertos de fármacos en la práctica clínica habitual. Comparación entre los stents liberadores de rapamicina y los stents liberadores de paclitaxol / Drug eluting stents: long term results in clinical practice. Comparison between rapamycin and paclitaxel eluting stents
Estudio retrospectivo en el que se seleccionó a todos los pacientestratados con stents recubiertos de rapamicina o paclitaxol durante los años 2003 y 2004 en nuestro centro. Analizamos la incidencia de eventos cardíacos mayores adversos en el total de pacientes y estudiamos si hubo diferencias entre ambos tipos de stents.
Resultados:
Se incluyó a 170 pacientes, 98 tratados con stent de rapamicina y 72 con stent de paclitaxol, con un seguimiento medio de 395 días. No hubo diferencias demográficas entre ambos grupos ni en las variables relacionadas con el procedimiento. La incidencia de eventos cardíacos mayores fue del 3,5% (el 2,0% en el grupo rapamicina y el 5,6% en el de paclitaxol; p = 0,43).
Drug eluting stents have demonstrated their superiority versus bare metalstents in the reduction of restenosis and major adverse cardiac events. Most studies do not identificate differences between rapamycin and paclitaxel eluting stent. Patients and
method:
Retrospective study. We identified all patients treated with rapamycin eluting stents or paclitaxel eluting stents during 2003 and 2004 in our center. We analized major adverse cardiac events incidence in the whole group and we investigated for differences between paclitaxel and rapamicin groups.
Results:
170 patients were included. 98 treated with rapamycin eluting stents and 72 with paclitaxel eluting stents. Medium follow up was 365 days. There were no differences between groups in demographic or periprocedural variables. The incidence of major adverse cardiac events was 3.5% in the entire group (2.0% in rapamycin group and 5.6% in paclitaxel group; p = 0.43).
Conclusions:
Drug eluting stents show a low incidence of major adverse cardiac events when they are utilized in usual clinical practice. With regard to this, we have not found differences between most used devices in our environment, rapamycin eluting stents and paclitaxel eluting stents
