Polygodial, the fungitoxic component from the Brazilian medicinal plant Polygonum punctatum
Alves, Tânia Maria de Almeida; Ribeiro, Fabiane Lacerda; Kloos, Helmut; Zani, Carlos Leomar.
Mem. Inst. Oswaldo Cruz;
96(6): 831-833, Aug. 2001. ilus
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| LILACS | ID: lil-298604
Polygonum punctatum (Polygonaceae) is an herb known in some regions of Brazil as "erva-de-bicho" and is used to treat intestinal disorders. The dichloromethane extract of the aerial parts of this plant showed strong activity in a bioautographic assay with the fungus Cladosporium sphaerospermum. The bioassay-guided chemical fractionation of this extract afforded the sesquiterpene dialdehyde polygodial as the active constituent. The presence of this compound with antibiotic, anti-inflammatory and anti-hyperalgesic properties in "erva-de-bicho" may account for the effects attributed by folk medicine to this plant species
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