Neurocysticercosis: relationship between Taenia antigen levels in CSF and MRI / Neurocisticercose: relação entre antígeno da Taenia no líquido cefalorraquidiano e ressonância magnética
Abraham, Ronaldo; Livramento, José Antonio; Leite, Cláudia da Costa; Pardini, Alessandra Xavier; Vaz, Adelaide José; Machado, Luís dos Ramos.
Arq. neuropsiquiatr;
68(1): 07-11, Feb. 2010. ilus, tab
Artículo
en Inglés
| LILACS | ID: lil-541179
Objective:
To determine the relationship between Taenia antigen (TA) detection in cerebrospinal fluid (CSF) and magnetic resonance imaging (MRI) findings in patients with definite diagnosis of neurocysticercosis (NC).Method:
Sixty-three patients with definite diagnosis of NC were submitted to a MRI of the brain, and to a CSF examination, with a meticulous search for TA by ELISA.Results:
TA detection was positive in 36 patients (57.1 percent). A total of 836 lesions were analyzed, greatly within the cerebral parenchyma (98.7 of the lesions). Intact or non-degenerating cysts were the most common evolutive phase observed (50.4 percent of all lesions), 22.1 percent were degenerating cysts and 19.5 percent calcified cysts. We observed a significant relationship between TA levels detected and the total number of lesions and the number of non-degenerating cysts, but not with calcified lesions.Conclusion:
According to our results, we propose at least four important types of contribution (1) TA detection may allow etiologic diagnosis in transitional phases of NC, with non-characteristic images; (2) in final stages of evolution of cysticercoids in the CNS, lesions may not appear on CT or MRI, and TA detection may contribute to a definite etiologic diagnosis; (3) TA detection may permit diagnosis of NC in some patients with previous negative tests for antibody detection in CSF; (4) TA detection may represent an accurate marker of disease activity in the epileptic form of NC.
Biblioteca responsable:
BR1.1
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