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Cognitive impairment is correlated with reduced quality of life in patients with clinically isolated syndrome / Comprometimento cognitivo correlaciona-se com redução da qualidade de vida em pacientes com síndrome clinicamente isolada

Anhoque, Carolina Fiorin; Biccas-Neto, Laurentino; Domingues, Simone Cristina A.; Teixeira, Antônio Lúcio; Domingues, Renan Barros.
Arq. neuropsiquiatr; 71(2): 74-77, Feb. 2013. tab
Artículo en Inglés | LILACS | ID: lil-663917

OBJECTIVE:

To evaluate the quality of life (QoL) and potential QoL determinants in patients with clinically isolated syndrome (CIS).

METHODS:

Eighteen CIS patients and eighteen controls were submitted to QoL evaluation with Functional Assessment of Multiple Sclerosis QoL instrument (FAMS). Cognition was evaluated with specific battery tests; Anxiety and depression with Beck Anxiety (BAI) and Depression (BDI) Inventories and Neurological disability with Guy's Neurological Disability Scale (GNDS).

RESULTS:

There was a significant difference in QoL between CIS patients and controls. CIS patients had worse performance in Paced Auditory Serial Addition 2 seconds (p=0.009) and fluency tests (p=0.0038). There was a significant difference in BAI (p=0.003), but no significant difference in BDI between patients and controls. There were significant correlations between QoL measure and verbal fluency and Stroop's test.

CONCLUSIONS:

Cognition, but not anxiety, depression and disability, was associated with reduced quality of life.
Biblioteca responsable: BR1.1