Characterization, chromosomal localization, and the complete 30-kb DNA sequence of the human Jagged2 (JAG2) gene.
Genomics
; 63(1): 133-8, 2000 Jan 01.
Article
en En
| MEDLINE
| ID: mdl-10662552
ABSTRACT
The genomic sequence of the human Jagged2 (JAG2) gene, which encodes a ligand for the Notch receptors, was determined. The 30-kb DNA sequence spanning the JAG2 gene contains 26 exons and a putative promoter region. Several potential binding sites for transcription factors, including NF-kappab, E47, E12, E2F, Ets-1, MyoD, and OCT-1, were found in the human JAG2 promoter region. The JAG2 gene was also mapped to the chromosomal region 14q32 using fluorescence in situ hybridization.
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Bases de datos:
MEDLINE
Asunto principal:
Cromosomas Humanos Par 14
/
Proteínas Portadoras
Límite:
Humans
Idioma:
En
Revista:
Genomics
Asunto de la revista:
GENETICA
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos