[Specific aspects and care of lung involvement in adults with cystic fibrosis]. / Spécificités et prise en charge de l'atteinte pulmonaire au cours de la mucoviscidose à l'âge adulte.
Rev Mal Respir
; 17(3 Pt 2): 758-78, 2000 Aug.
Article
en Fr
| MEDLINE
| ID: mdl-11076386
ABSTRACT
Respiratory impairment is present in almost all adult cystic fibrosis patients and makes the prognosis. Viscous, infected and abundant secretions, inflammation and bronchial oedema, bronchoconstriction and respiratory muscle fatigue lead to airway obstruction, bronchiectasis and respiratory failure. The disease is preferentially located in the upper lobes. Exacerbations of the disease are due to bronchial infections and are often responsible for drops of the respiratory function. Regular spirometric surveillance is fundamental for the prognosis and the assessment of the effects of the treatment. Among adult patients chronic colonisation with mucoid and often multiresistant strains of Pseudomonas Aeruginosa are common. It is treated with i.v. high doses antibiotic courses and nebulized antibiotics between i.v. courses. Respiratory failure may require long term oxygen and non invasive mechanical ventilation. Systemic hypervascularization around the bronchiectasis may lead to moderate to severe hemoptysis, which may require embolization. Pneumothorax are associated with poor prognosis and are treated by pleural drainage and if failure by thoracoscopy.
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Bases de datos:
MEDLINE
Asunto principal:
Neumonía
/
Insuficiencia Respiratoria
/
Bronquiectasia
/
Fibrosis Quística
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Humans
Idioma:
Fr
Revista:
Rev Mal Respir
Año:
2000
Tipo del documento:
Article