Systematic Review of Hirudin in Acute Coronary Syndromes and Percutaneous Coronary Intervention.
Curr Interv Cardiol Rep
; 3(2): 156-162, 2001 May.
Article
en En
| MEDLINE
| ID: mdl-11322919
ABSTRACT
Thrombin plays a key role in the pathogenesis of acute coronary syndromes because it is a potent platelet agonist and converts fibrinogen to fibrin. Hirudin is a powerful, direct, and specific antithrombin agent that can be used in many therapeutic scenarios in which heparin is routinely used. In this systemic review, we summarize evidence from randomized clinical trials evaluating the benefits and risks of recombinant hirudin for the treatment of acute coronary syndromes and patients undergoing percutaneous coronary intervention.
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Bases de datos:
MEDLINE
Tipo de estudio:
Clinical_trials
/
Systematic_reviews
Idioma:
En
Revista:
Curr Interv Cardiol Rep
Año:
2001
Tipo del documento:
Article
País de afiliación:
Reino Unido