Lymphocytic infundibulo-neurohypophysitis associated with recurrent optic neuritis.
Br J Neurosurg
; 15(2): 180-3, 2001 Apr.
Article
en En
| MEDLINE
| ID: mdl-11360389
ABSTRACT
A 38-year-old woman presented with diabetes insipidus. The T1-weighted images showed a loss of the hyperintense signal of the posterior pituitary and thickening of the pituitary stalk. DDAVP was started with the diagnosis of lymphocytic infundibulo-neurohypophysitis (LINH). Three months later, she complained of right visual acuity loss. MRI revealed right optic nerve swelling, compatible with the diagnosis of the retrobulbar optic neuritis. She had two other such episodes in the next 3 months. She developed a transient oculomotor and abducens nerve palsies as well. Each time the symptoms disappeared with corticosteroid therapy. The pituitary stalk became normal in size 6 months later. LINH and recurrent optic neuritis occurred in a short duration. Accordingly, a common causative background is suspected. Since the auto-immune process has been hypothesized as a cause of optic neuritis, our case may present further clinical evidence to support the hypothesis of an auto-immune mechanism for LINH.
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Bases de datos:
MEDLINE
Asunto principal:
Enfermedades de la Hipófisis
/
Neurohipófisis
/
Enfermedades Autoinmunes
/
Neuritis Óptica
Tipo de estudio:
Diagnostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Br J Neurosurg
Asunto de la revista:
NEUROCIRURGIA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Japón