Hyperlipidaemia and pancreatitis associated with oral contraceptive therapy.
J Assoc Physicians India
; 23(2): 161-4, 1975 Feb.
Article
en En
| MEDLINE
| ID: mdl-1184540
ABSTRACT
PIP Case reports of 2 patients who developed pancreatitis and hyperlipidemia while using oral contraceptives are presented. The 1st patient had been taking Ovulen for 2 years when severe abdominal pain suddenly developed. Initially cholecystitis was diagnosed. Symptoms subsided within 1 week but recurred 2 months later, when the white blood count was increased to 16,400/cubic mm. Serum was grossly lipemic with a triglyceride level of 3500 mg% and serum cholesterol 560 mg%. 3 days later triglycerides had fallen to 400 mg% and cholesterol to 270 mg%. Cholecystography was normal. The pain had subsided. Symptoms have not recurred since stopping use of Ovulen. The 2nd patient was admitted with severe abdominal pain of 48 hours duration. Similar attacks of pain had occurred previously but had been of short duration. She had been taking Ovulen for 3 years. White blood count was increased to 18,000. Serum was grossly lipemic. Serum glyceride concentration was 7000 mg% and cholesterol 1200 mg%. Afer 3 days triglycerides were 500 mg% and cholesterol 475 mg%. Pancreatitis was diagnosed. Therapy was Ryles tube suction, atropine, intravenous saline, and a broad spectrum antibiotic. Symptoms subsided in 10 days. The hyperlipidemia is thought to have been a primary condition causing the pancreatitis. [Patients known to have such a condition should avoid use of oral contraceptives.^ieng
Palabras clave
Biology; Contraception; Contraceptive Agents, Estrogen--side effects; Contraceptive Agents, Female--side effects; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--side effects; Contraceptive Methods--side effects; Ethynodiol Diacetate--side effects; Family Planning; Hematological Effects; Hemic System; Lipid Metabolic Effects; Lipids; Mestranol--side effects; Oral Contraceptives, Combined; Oral Contraceptives--side effects; Physiology
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Bases de datos:
MEDLINE
Asunto principal:
Pancreatitis
/
Anticonceptivos Orales
/
Hiperlipidemias
Tipo de estudio:
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
J Assoc Physicians India
Año:
1975
Tipo del documento:
Article