Evaluation of the C6 peptide enzyme-linked immunosorbent assay for individuals vaccinated with the recombinant OspA vaccine.
J Clin Microbiol
; 40(7): 2591-3, 2002 Jul.
Article
en En
| MEDLINE
| ID: mdl-12089281
ABSTRACT
The C6 enzyme-linked immunosorbent assay (ELISA), based on a peptide (C6) that reproduces the sequence of invariable region 6 of VlsE, the antigenic variation protein of Borrelia burgdorferi, has been shown to be a sensitive and specific test for the serologic diagnosis of Lyme disease. We now report that none of 29 uninfected individuals vaccinated with the recombinant OspA vaccine had an antibody response to the C6 peptide. The C6 peptide ELISA can be used to diagnose Lyme disease in patients who have received the OspA vaccine.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Proteínas de la Membrana Bacteriana Externa
/
Proteínas Bacterianas
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Ensayo de Inmunoadsorción Enzimática
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Enfermedad de Lyme
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Vacunas contra Enfermedad de Lyme
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Borrelia burgdorferi
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Lipoproteínas
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Antígenos de Superficie
Tipo de estudio:
Observational_studies
Límite:
Humans
Idioma:
En
Revista:
J Clin Microbiol
Año:
2002
Tipo del documento:
Article
País de afiliación:
Estados Unidos