[Preventing and treating effects of "changkun granules" on experimental acute renal failure induced by cisplatin in rats].

ABSTRACT

OBJECTIVE: To study the preventing and treating effects of "Changkun Granules" in experimental acute renal failure(ARF) induced by cisplatin in rats. METHODS: The ARF rats were administered the "Changkun Granules". Serum BUN and SCr of all the rats were measured and the renal morphology was evaluated. RESULTS: Serum BUN level in the "Changkun Granules" group was lower than the one in cisplatin group. "Changkun Granules" could also improve renal histology damage. CONCLUSION: The results indicated that "Changkun Granules" had certain protective effect on experimental ARF.