Suboptimal performance on neuropsychological tests in patients with suspected chronic toxic encephalopathy.
Neurotoxicology
; 24(4-5): 547-51, 2003 Aug.
Article
en En
| MEDLINE
| ID: mdl-12900068
ABSTRACT
Suboptimal performance during neuropsychological testing can seriously complicate assessment in behavioral neurotoxicology. We present data on the prevalence of suboptimal performance in a group of Dutch patients with suspected chronic toxic encephalopathy (CTE) after long-term occupational exposure to solvents. One hundred and forty-five subjects referred to one of two Dutch national assessment centers for CTE were administered the Amsterdam Short-Term Memory Test (ASTM) and the Test of Memory Malingering (TOMM), two tests specifically developed for the detection of suboptimal performance. For both tests, very cautious cut-off scores were chosen with a specificity of 99%. Results indicated that suboptimal performance appears to be a substantial problem in this group of patients with suspected CTE after long-term exposure to organic solvents. Only 54% of our subjects obtained normal scores on both tests of malingering, i.e. at or above cut-off score. The two tests seemed to measure the same concept in that nearly all the subjects with low TOMM scores also had low ASTM scores. However, a higher proportion of subjects scored below the cut-off on the ASTM than on the TOMM.
Buscar en Google
Bases de datos:
MEDLINE
Asunto principal:
Solventes
/
Exposición Profesional
/
Síndromes de Neurotoxicidad
/
Pruebas Neuropsicológicas
Tipo de estudio:
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Neurotoxicology
Año:
2003
Tipo del documento:
Article
País de afiliación:
Países Bajos