[Severe course and contingent risk factors in optic neuropathy and myelopathy after tuberculostatics]. / Schwerwiegender Verlauf und belastende Faktoren bei Optikusneuropathie und Myelopathie durch Tuberkulostatika.
Ophthalmologe
; 100(11): 967-70, 2003 Nov.
Article
en De
| MEDLINE
| ID: mdl-14669033
ABSTRACT
A male patient with tuberculous lymphadenopathy was treated with a four-fold therapy of ethambutol, isoniacide, rifampicin and pyracinamide. After 10 weeks the patient suffered from photophobia. Although ethambutol was discontinued vision decreased and visual field defects occurred as well as signs of myelopathy. Isoniacide was then discontinued and in the subsequent phase the vision was slowly restored over a period of 36 months. The combined toxicity of ethambutol and isoniacide seems to have been the main cause of the severe and protracted optic neuropathy.
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Bases de datos:
MEDLINE
Asunto principal:
Gestión de Riesgos
/
Enfermedades de la Médula Espinal
/
Tuberculosis Ganglionar
/
Enfermedades del Nervio Óptico
/
Fotofobia
/
Antituberculosos
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
De
Revista:
Ophthalmologe
Asunto de la revista:
OFTALMOLOGIA
Año:
2003
Tipo del documento:
Article