Performance of IgG avidity in an area endemic for schistosomiasis in Egypt.
East Mediterr Health J
; 8(1): 172-80, 2002 Jan.
Article
en En
| MEDLINE
| ID: mdl-15330573
ABSTRACT
We assessed the performance of IgG avidity in the diagnosis of acute, chronic and recent (reinfection) on top of chronic schistosomal infections in patients treated with praziquantel. Immunoglobulin levels were studied in 111 patients with Schistosoma mansoni infection and 28 partially cured patients (not responding to the first dose of praziquantel treatment and almost cured after a second one). Before treatment all patients with schistosomiasis had elevated IgG levels, 75% of them also had increased IgM levels. Avidity index was high among all age groups. The increased IgM/IgG ratio and avidity index among children with schistosomiasis before treatment support the idea of reinfection. Treatment had no significant effect on the studied parameters. We conclude that unlike IgM and IgG antibody levels, IgG avidity test cannot be used to distinguish between recent and chronic infections.
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Bases de datos:
MEDLINE
Asunto principal:
Schistosoma mansoni
/
Esquistosomiasis mansoni
/
Inmunoglobulina G
/
Ensayo de Inmunoadsorción Enzimática
/
Anticuerpos Antiprotozoarios
Límite:
Adolescent
/
Adult
/
Aged
/
Animals
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Africa
Idioma:
En
Revista:
East Mediterr Health J
Asunto de la revista:
MEDICINA
Año:
2002
Tipo del documento:
Article
País de afiliación:
Egipto