Regional and generalized changes in cytosolic free calcium in monocytes during phagocytosis.
Infect Immun
; 60(3): 1244-8, 1992 Mar.
Article
en En
| MEDLINE
| ID: mdl-1541541
ABSTRACT
We measured and visualized cytosolic free calcium ([Ca2+]i) in individual human peripheral blood monocytes during phagocytosis by using the fluorescent indicator fura-2. Monocytes exhibit a rapid rise in [Ca2+]i from a basal level of 75 +/- 11 nM to a peak level of 676 +/- 78 nM (means +/- standard errors of the means; P less than 0.001) by 34 +/- 5 s after contact with opsonized zymosan particles, and a thin rim of high [Ca2+]i was observed surrounding the ingested particle.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Fagocitosis
/
Monocitos
/
Calcio
/
Citosol
Límite:
Humans
Idioma:
En
Revista:
Infect Immun
Año:
1992
Tipo del documento:
Article