The amoeba enigma.
Parasitol Today
; 8(12): 402-6, 1992 Dec.
Article
en En
| MEDLINE
| ID: mdl-15463553
ABSTRACT
After more than 70 years of intermittent debate over the true relationship between the 'pathogenic' and 'non-pathogenic' forms of Entamoeba histolytica, the application of molecular biology has finally yielded an unambiguous answer these are not interconvertible phenotypes of the same parasite, a kind of unicellular Jekyll and Hyde, but two quite distinct genetic entities that just happen to look the same. But given the overwhelming evidence now available from gene sequences, pointing to an evolutionary divergence some tens of millions of years ago, why is it that certain eminent workers in the field are still claiming that, at least in vitro, conversion between the two phenotypes can take place? In this article Bill Spice and John Ackers review recent developments in the molecular biology of E. histolytica and assess the continuing controversy over the status of this enigmatic parasite.
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Bases de datos:
MEDLINE
Idioma:
En
Revista:
Parasitol Today
Asunto de la revista:
PARASITOLOGIA
Año:
1992
Tipo del documento:
Article
País de afiliación:
Reino Unido