DNA polymerase clamp loaders and DNA recognition.
FEBS Lett
; 579(4): 863-7, 2005 Feb 07.
Article
en En
| MEDLINE
| ID: mdl-15680964
ABSTRACT
Clamp loaders are heteropentameric ATPase assemblies that load sliding clamps onto DNA and are critical for processive DNA replication. The DNA targets for clamp loading are double-stranded/single-stranded junctions with recessed 3' ends (primer-template junctions). Here, we briefly review the crystal structures of clamp loader complexes and the insights they have provided into the mechanism of the clamp loading process.
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Bases de datos:
MEDLINE
Asunto principal:
Adenosina Trifosfatasas
/
Proteínas de Unión al ADN
/
ADN Polimerasa Dirigida por ADN
/
Replicación del ADN
Idioma:
En
Revista:
FEBS Lett
Año:
2005
Tipo del documento:
Article
País de afiliación:
Estados Unidos