High-dose-rate interstitial brachytherapy in the management of carcinoma of the uterine cervix and other gynecologic malignancies.
J Med Assoc Thai
; 88(8): 1045-50, 2005 Aug.
Article
en En
| MEDLINE
| ID: mdl-16404830
ABSTRACT
OBJECTIVE:
To report technique and experience of high-dose-rate (HDR) interstitial brachytherapy in the treatment of cervical carcinoma and other gynecologic malignancies. MATERIAL ANDMETHOD:
Between April 2003 and October 2004, ten patients (7-cervical carcinoma, 3-vaginal stump carcinoma) were treated with interstitial implant. Indications for implant include previous hysterectomy and previous pelvic radiation. Patient characteristics, implant technique, and initial outcomes were reported.RESULTS:
Transperineal interstitial implant was performed using fluoroscopy-guided technique. Brachytherapy dose/fraction ranged from 500-750 cGy for 1 to 6 fractions. Combined external beam radiation was given in 8 patients. After 5-21 months follow-up, all the patients were alive. Local control was achieved in 9 patients. One patient had persistent disease at the implant site. No acute complication from the procedure or serious late complication was observed.CONCLUSION:
Interstitial implant can be a treatment option in patients with gynecologic malignancies who have limitations with standard intracavitary insertion. This technique is feasible, providing good local control without serious complications. However, long-term follow-up is needed.
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Bases de datos:
MEDLINE
Asunto principal:
Radioisótopos
/
Braquiterapia
/
Carcinoma
/
Neoplasias del Cuello Uterino
/
Cuello del Útero
Tipo de estudio:
Observational_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
J Med Assoc Thai
Año:
2005
Tipo del documento:
Article
País de afiliación:
Tailandia