Study of hypothalamic metabolism in cluster headache by proton MR spectroscopy.
Neurology
; 66(8): 1264-6, 2006 Apr 25.
Article
en En
| MEDLINE
| ID: mdl-16636250
ABSTRACT
The authors used 1H-MRS to investigate hypothalamic metabolism in 26 patients with cluster headache (CH) and 12 healthy subjects. Hypothalamic N-acetylaspartate/creatine was reduced in patients with CH vs controls (p < 0.01). Dividing the patients into episodic CH outside- and in-cluster periods and chronic CH, the hypothalamic N-acetylaspartate/creatine in all three subgroups of patients was reduced. The reduction of the neuronal marker N-acetylaspartate is consistent with hypothalamic neuronal dysfunction in patients with CH.
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Bases de datos:
MEDLINE
Asunto principal:
Espectroscopía de Resonancia Magnética
/
Cefalalgia Histamínica
/
Hipotálamo
Límite:
Adult
/
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Neurology
Año:
2006
Tipo del documento:
Article
País de afiliación:
Italia